Results 111 to 120 of about 2,033,584 (167)

Neutrophilic asthma: advances in experimental models from pathogenesis to therapeutic translation

Molecular Medicine
Background Neutrophilic asthma (NA) is a severe and therapy-resistant asthma endotype marked by persistent airway inflammation, neutrophil infiltration, and limited response to glucocorticoids.
Jialin Yao, Jingjing Lu, Jing Gao, Ximing Liao, Di Wu, Muyun Wang, Qiang Li, Wei Gao   +7 more
doaj   +1 more source

A community study of factors related to poorly controlled asthma among Brazilian urban children. [PDF]

, 2012
BACKGROUND: Asthma constitutes a serious public health problem in many regions of the world, including the city of Salvador, State of Bahia-Brazil. The purpose of this study was to analyse the factors associated with poor asthma control.
Cruz, Alvaro A., Dias Karen Conceição, Alcântara-Neves Neuza M., Barreto Maurício L., da Cunha, Sergio S, Dias, Karen Conceição, Amorim, Leila D., de Magalhães Simões, Silvia, Cruz Álvaro A., Amorim Leila D., Amorim, Leila D, Karen Conceição Dias, Barreto, Maurício L, Alcântara-Neves, Neuza M, Cunha, Sergio S. da, Barreto, Mauricio L., Maurício L Barreto, Simões Silvia de Magalhães, Rodrigues Laura C., Álvaro A Cruz, Silvia de Magalhães Simões, Sergio S da Cunha, Leila D Amorim, Laura C Rodrigues, Alcântara, Neuza Maria Neves, Simões, Silvia de Magalhães, Cruz, Álvaro A, da Cunha Sergio S., Rodrigues, Laura C., Rodrigues, Laura C, Neuza M Alcântara-Neves   +30 more
core   +1 more source

Exhaled nitric oxide as a predictor of exacerbation in children with moderate-to-severe asthma: a prospective, 5-month study

, 2009
Background: Inhaled corticosteroids (ICSs) are recommended as the first line of treatment in children with moderate-to-severe asthma. Exhaled nitric oxide (ENO) has been proposed as a clinically useful marker of control that might help identify patients ...
CABRAL, Anna Lucia B., BARBIROTTO, Rosa M., MARTINS, Milton A., VOLLMER, William M., Anna Lúcia B. Cabral, Milton A. Martins, William M. Vollmer, Rosa M. Barbirotto   +7 more
core   +1 more source

Phagocytosis, bacterial killing, and cytokine activation of circulating blood neutrophils in horses with severe equine asthma and control horses

, 2018
OBJECTIVE To evaluate in vitro phagocytosis and bactericidal activity of circulating blood neutrophils in horses with severe equine asthma and control horses and to determine whether circulating blood neutrophils in horses with severe equine asthma have ...
Johanne M. Vanderstock, Jean-Pierre Lavoie, Marie-Pier Lecours, Daniel Jean, Marcelo Gottschalk, Annouck Lavoie-Lamoureux, Mariela Segura   +6 more
core   +1 more source

Immunoproteomics reveal increased serum IgG3/5 binding to Dermatophagoides and yeast protein antigens in severe equine asthma in a preliminary study. [PDF]

Front Immunol, 2023
Schnabel CL, Jentsch MC, Lübke S, Kaiser-Thom S, Gerber V, Vrtala S, Huang HJ, Rhyner C, Wagner B, Hoffmann R, Volke D.   +10 more
europepmc   +1 more source

Severe asthma in children

, 2017
Most children with asthma have their disease easily controlled if low-dose inhaled corticosteroids (ICSs) are regularly and correctly administered. If a child presents with asthma which is apparently resistant to therapy with high-dose ICS and other ...
Andrew Bush, Bush, A, Louise Fleming, Fleming, L, Sejal Saglani, Saglani, S   +5 more
core   +1 more source

Equine alveolar macrophages and monocyte-derived macrophages respond differently to an inflammatory stimulus

PLoS ONE, 2023
Alveolar macrophages (AMs) are the predominant innate immune cell in the distal respiratory tract. During inflammatory responses, AMs may be supplemented by blood monocytes, which differentiate into monocyte-derived macrophages (MDMs).
Heng Kang, Gary Kwok Cheong Lee, Dorothee Bienzle, Luis G. Arroyo, William Sears, Brandon N. Lillie, Janet Beeler-Marfisi   +6 more
doaj  

Assessment of pulmonary vascular smooth muscle remodeling in severe equine asthma

, 2017
Severe equine asthma (SEA) is characterized by reversible airway obstruction and hypoxemia. Pulmonary hypoxic vasoconstriction occurs during SEA exacerbation, inducing pulmonary hypertension (PH). However, PH is only partially reversed by oxygen administration, and other etiological factors are uninvestigated (Dixon 1978).
Ceriotti, Serena, Bullone, Michela, Ferrucci, Francesco, Lavoie, Jean-Pierre   +3 more
openaire   +2 more sources

Publication Only

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source

Severe Asthma Questionnaire (SAQ) and Asthma Control Questionnaire (ACQ) as Early Predictors of Biologic Response in Severe Asthma [PDF]

Drew Davies,1 Joseph W Lanario,2,3 Michael E Hyland,2 Matthew Masoli1,3 1Department of Respiratory Medicine, Royal Devon and Exeter Hospital, University of Exeter, Exeter, UK; 2Faculty of Health, University of Plymouth, Plymouth, UK; 3University of ...
Lanario JW, Masoli M, Hyland ME, Davies D   +3 more
core