Results 101 to 110 of about 1,927,081 (168)

Clinical variability of equine asthma phenotypes and analysis of diagnostic steps in phenotype differentiation

Acta Veterinaria Scandinavica
Background Equine asthma is a common, non-infectious, chronic lung disease that affects up to 80% of the horse population. Strict phenotyping and identification of subclinically asthmatic horses can be challenging.
Lia Kristin Meiseberg, Julien Delarocque, Nicole de Buhr, Bernhard Ohnesorge   +3 more
doaj   +1 more source

Rhinosinusitis Predispose Asthmatic Patients to Severe Bronchial Asthma [PDF]

In this study, we evaluated the relationship between rhinosinusitis to the severity of asthma in asthmatic patients. This cross-sectional study was conducted on 90 patients with asthma referring to Imam Khomeini Hospital in Ardabil city.
غفرانی, محسن, اناری, حسن, اعظمی, احد, حبیب زاده, الهام, شرقی, افشان   +4 more
core   +1 more source

Single-cell profiling of bronchoalveolar cells reveals a Th17 signature in neutrophilic severe equine asthma [PDF]

Severe equine asthma (SEA) is a complex respiratory condition characterized by chronic airway inflammation. It shares many clinical and pathological features with human neutrophilic asthma, making it a valuable model for studying this condition. However,
Jagannathan, Vidhya, Sage, Sophie E., Leeb, Tosso, Gerber, Vinzenz   +3 more
core   +2 more sources

Inhaled ciclesonide is efficacious and well tolerated in the treatment of severe equine asthma in a large prospective European clinical trial:Inhaled ciclesonide in horses with severe equine asthma

, 2021
Background: Ciclesonide is a glucocorticoid prodrug, already registered for human use. Due to its mode of action and inhaled route of administration, it was considered an appropriate treatment option for horses with severe equine asthma. Although the efficacy of inhaled ciclesonide has been demonstrated in horses with asthma exacerbations under ...
Pirie, Scott; id_orcid 0000-0003-4299-4077, Mueller, H-W., Engel, Odilo, Albrecht, Beate, Salis-Soglio, M. von   +4 more
openaire   +1 more source

MARCKS protein is a potential target in a naturally occurring equine model of neutrophilic asthma

Respiratory Research
Background Asthma is a chronic inflammatory airway disease that affects millions of people worldwide. Horses develop asthma spontaneously and serve as a relevant model for multiple phenotypes and endotypes of human asthma.
Haleigh E. Conley, Kaori Uchiumi Davis, Kenneth B. Adler, Jean-Pierre Lavoie, M. Katie Sheats   +4 more
doaj   +1 more source

Development of a comprehensive protein microarray for immunoglobulin E profiling in horses with severe asthma

Journal of Veterinary Internal Medicine, 2019
Background Severe asthma in horses, known as severe equine asthma (SEA), is a prevalent, performance‐limiting disease associated with increased allergen‐specific immunoglobulin E (IgE) against a range of environmental aeroallergens.
Samuel White, Meriel Moore‐Colyer, Eliane Marti, Laurent Coüetil, Duncan Hannant, Eric A. Richard, Marcos Alcocer   +6 more
doaj   +1 more source

Severe asthma in children

, 2017
Most children with asthma have their disease easily controlled if low-dose inhaled corticosteroids (ICSs) are regularly and correctly administered. If a child presents with asthma which is apparently resistant to therapy with high-dose ICS and other ...
Andrew Bush, Bush, A, Louise Fleming, Fleming, L, Sejal Saglani, Saglani, S   +5 more
core   +1 more source

Neutrophilic asthma: advances in experimental models from pathogenesis to therapeutic translation

Molecular Medicine
Background Neutrophilic asthma (NA) is a severe and therapy-resistant asthma endotype marked by persistent airway inflammation, neutrophil infiltration, and limited response to glucocorticoids.
Jialin Yao, Jingjing Lu, Jing Gao, Ximing Liao, Di Wu, Muyun Wang, Qiang Li, Wei Gao   +7 more
doaj   +1 more source

Severe Asthma Questionnaire (SAQ) and Asthma Control Questionnaire (ACQ) as Early Predictors of Biologic Response in Severe Asthma [PDF]

Drew Davies,1 Joseph W Lanario,2,3 Michael E Hyland,2 Matthew Masoli1,3 1Department of Respiratory Medicine, Royal Devon and Exeter Hospital, University of Exeter, Exeter, UK; 2Faculty of Health, University of Plymouth, Plymouth, UK; 3University of ...
Lanario JW, Masoli M, Hyland ME, Davies D   +3 more
core  

People with moderate to severe asthma [PDF]

Updated Aug. 27, 2020This information is based on what we currently know about the spread and severity of coronavirus disease 2019 (COVID-19).Risk of Severe Illness from COVID-19 -- Treatment -- Prepare for COVID-19 -- Follow your Asthma Action Plan ...

core   +6 more sources