Results 141 to 150 of about 1,804,243 (315)

Intermittent preventive treatment of malaria provides substantial protection against malaria in children already protected by an insecticide-treated bednet in Burkina Faso: a randomised, double-blind, placebo-controlled trial. [PDF]

, 2011
BACKGROUND: Intermittent preventive treatment of malaria in children (IPTc) is a promising new approach to the control of malaria in areas of seasonal malaria transmission but it is not known if IPTc adds to the protection provided by an insecticide ...
Issa N Ouédraogo, Tiono, Alfred B, Youssouf Kaboré, Daniel Chandramohan, Yaro Jean Baptiste, Ouédraogo, Amidou Z, Soulama, Issiaka, Konaté Amadou T., Issa N. Ouédraogo, Ouédraogo Issa N., Amadou T Konaté, Yaro, Jean Baptiste, Gansané, Adama, Ouédraogo Espérance, Alfred B. Tiono, Jean Baptiste Yaro, Diadier A. Diallo, Greenwood, Brian, Diallo Diadier A., Espérance Ouédraogo, Chandramohan Daniel, Ouédraogo, Alphonse, Cousens, Simon, Diadier A Diallo, Greenwood Brian, Alfred B Tiono, David T. Kangoyé, Ouédraogo, Espérance, Chandramohan, Daniel, Paul J Milligan, Kaboré, Youssouf, Ouédraogo Alphonse, Amadou T. Konaté, Sirima Sodiomon B., Amidou Z Ouédraogo, Kangoyé, David T, Sirima, Sodiomon B, Diarra, Amidou, Ouédraogo, Issa N, Paul J. Milligan, Sodiomon B. Sirima, Kangoyé David T., Milligan Paul J., Milligan, Paul J, Cousens Simon, Alphonse Ouédraogo, Simon Cousens, Diallo, Diadier A, Brian Greenwood, Amidou Z. Ouédraogo, Adama Gansané, Tiono Alfred B., Kaboré Youssouf, Sodiomon B Sirima, Gansané Adama, David T Kangoyé, Issiaka Soulama, Ouédraogo Amidou Z., Soulama Issiaka, Amidou Diarra, Konaté, Amadou T, Diarra Amidou   +61 more
core   +1 more source

Repurposing antimicrobial agents for neuroprotection: Mechanisms, clinical potential, and challenges

Neuroprotection, EarlyView.
Antimicrobial agents exert neuroprotective effects through modulation of interconnected pathways. Tetracyclines, macrolides, antimalarial agents, sulfones, and antiparasitic agents suppress neuroinflammation, oxidative stress, and apoptosis while preserving mitochondrial function and neurotransmission.
Mohammad Amin Manavi, Mohammadreza Salehi, Razieh Mohammad Jafari, Ramin Goudarzi, Saman Khosravi, Ahmad Reza Dehpour   +5 more
wiley   +1 more source

Enhanced decision models for the diagnosis and treatment of malaria in an age of ACTs [PDF]

New diagnostics and treatments for malaria have renewed hope in the developing world as they promise relief from the debilitating effects of this illness.
Lubell, Yoel
core   +1 more source

Bioarcheological Insights From Fragmented Remains: Using Dental Health to Understand the Punic Necropolis of Monte Luna

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT To investigate oral health in the fragmented human remains from the Punic necropolis of Monte Luna, Sardinia, and evaluate what dental pathologies reveal about lifeways and diet. Human remains from 227 individuals recovered from 70 tombs were analyzed, including 21 females, 16 males (> 15 years), and 59 non‐adults (1–15 years).
Rossella Paba, Anna Willis, Kate Domett
wiley   +1 more source

The Mexico City Policy in US Development Policy and Its Backlash‐Frontlash‐Logic

Public Administration and Development, EarlyView.
ABSTRACT The Mexico City Policy provides for the discontinuation of U.S. government funding for foreign non‐governmental organizations (NGOs) that provide legal abortion services. While Republican administrations have repeatedly pushed for the introduction of the Mexico City Policy after their re‐election, those regulations have been rescinded by ...
Thomas Lange
wiley   +1 more source

Severe malarial anaemia in childhood is associated with decreased long-term household wealth

BMC Public Health
Background Severe malarial anaemia and cerebral malaria can result in long-term cognitive, behavioral, and mental health impairments that may influence future household wealth. However, the magnitude and mechanisms of this impact on wealth remain unclear.
Perez N. Ochanda, Arild Aakvik, Paul Bangirana, Dibyadyuti Datta, Kagan A. Mellencamp, Chandy C. John, Bjarne Robberstad   +6 more
doaj   +1 more source

Sickle Cell Disease: Historical Overview and Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Treating severe and complicated malaria

BMJ, 2004
Clinical attacks are usually uncomplicated and can be managed with an effective oral drug. Most occur in sub-Saharan Africa. Of the 200 million episodes of clinical malaria that occur each year among African children, 4-6 million are severe and life threatening, and most of the 1 million deaths from malaria worldwide are in Africa.1 Although some risk ...
openaire   +3 more sources

Large language models unlock large text corpora in the search for data on medicinal plants and fungi

PLANTS, PEOPLE, PLANET, EarlyView.
Millions of people worldwide depend on plants and fungi for their healthcare needs, yet our understanding of which species are used medicinally—and how—remains fragmented and incomplete. As part of Kew's Plants for Health service, we developed a pipeline to mine large text corpora for information on natural products, initially focusing on the medicinal
Adam Richard‐Bollans, Francesco Civita, Tiziana A. Cossu, Ifra Saifi, Kristina Patmore, Caroline Wilkinson, Bob Allkin   +6 more
wiley   +1 more source

Apigenin Protects Hypertensive Intracerebral Hemorrhage by Regulating Trx1 Through Binding to PRDX2

Phytotherapy Research, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) remains the most severe stroke subtype with high mortality and disability rates. Although apigenin has shown cerebroprotective potential in preclinical studies, its mechanism of action, particularly in hypertensive ICH, remains poorly understood.
Hao‐chen Xu, Ming Liu, Ying‐ying Sun, Jie‐Dan Ping, Qing‐hua Cui, Jing‐zhou Chen, Hao Li   +6 more
wiley   +1 more source