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Apolipoprotein-E4: risk of severe malaria and mortality and cognitive impairment in pediatric cerebral malaria. [PDF]
Pediatr ResLima-Cooper G +11 more
europepmc +1 more source
Management of Severe Malaria [PDF]
Evidence-Based Critical Care, 2019 Imported malaria is the principal, preventable, life-threatening infection among US travelers. Using a case scenario, we discuss the most recent information on the management and treatment of Severe Malaria.
Jorge Hidalgo +2 more
semanticscholar +3 more sources
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The Indian Journal of Pediatrics, 2004
Falciparum malaria affect all ages with multiple-systemic complications which varies in different age group. We studied 242 children with complicated Falciparum malaria with a median age of 6.5 years to look for occurrence of different complications in younger and older age groups and overall mortality picture.
Niranjan Mohanty +3 more
openaire +3 more sources
Falciparum malaria affect all ages with multiple-systemic complications which varies in different age group. We studied 242 children with complicated Falciparum malaria with a median age of 6.5 years to look for occurrence of different complications in younger and older age groups and overall mortality picture.
Niranjan Mohanty +3 more
openaire +3 more sources
Severe malaria: update on pathophysiology and treatment.
Current Opinion in Infectious Diseases, 2019PURPOSE OF REVIEW Malaria threatens the lives of over 200 million individuals with the disease each year. Plasmodium falciparum is the predominant cause of severe malaria which may be lethal and result in neurocognitive sequelae despite appropriate ...
Josef A. Brejt, L. Golightly
semanticscholar +1 more source
Severe hyponatraemia in malaria
Journal of Infection, 1991We report a case of severe hyponatraemia and hypoglycaemia in a patient with complicated falciparum malaria. The use of large volumes of intravenous dextrose as a diluent for quinine may lead to fluid overload and exacerbate hyponatraemia.
Saye Khoo, E.G.L. Wilkins
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The Microcirculation in Severe Malaria
Microcirculation, 2004ABSTRACTSevere malaria in humans and animals is initiated by interactions between malaria‐infected cells, host blood cells (including monocytes, T cells and platelets) and endothelial cells of the microcirculation. Adhesion to vascular cells, and possible vascular obstruction in severe human disease, involves interaction between host receptors and ...
Nicholas H. Hunt +2 more
openaire +3 more sources
Tracking severe malaria disease
Science, 2021Malaria infection prevalence predicts malaria mortality—at least for ...
Laurence Slutsker, Terrie E. Taylor
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The Indian Journal of Pediatrics, 2004
Prompt diagnosis and early institution of therapy is an important determinant of outcome in severe falciparum malaria. Thick smears are the gold standard for diagnosis; in situations where reliable microscopy is not available, tests based on HRP-2 antigen/parasite LDH are useful. As there is widespread resistance to chloroquine in P falciparum in India,
openaire +3 more sources
Prompt diagnosis and early institution of therapy is an important determinant of outcome in severe falciparum malaria. Thick smears are the gold standard for diagnosis; in situations where reliable microscopy is not available, tests based on HRP-2 antigen/parasite LDH are useful. As there is widespread resistance to chloroquine in P falciparum in India,
openaire +3 more sources
For severe malaria, artesunate is the answer
The Lancet, 2010The zoonotic parasite Plasmodium knowlesi has become the most common cause of human malaria in Malaysia and is present throughout much of southeast Asia. No randomised controlled trials have been done to identify the optimum treatment for this emerging infection. We aimed to compare artesunate-mefloquine with chloroquine to define the optimum treatment
openaire +4 more sources