Results 71 to 80 of about 991,555 (375)

Clinical Presentation and Long-Term Outcomes of Systemic Sclerosis Portuguese Patients from a Single Centre Cohort: A EUSTAR Registration Initiative

Acta Médica Portuguesa, 2018
Introduction: Systemic sclerosis is a complex disorder that requires systematic screening. Our objective is to report the European Scleroderma Trials and Research group centre affiliation and its impact in our clinical practice. Material and Methods: The
Carolina Vidal, Carina Ruano, Vera Bernardino, Pedro Lavado Carreira, Ana Lladó, Maria Céu Santos, Heidi Gruner, António Panarra, Nuno Riso, Maria Francisca Moraes-Fontes   +9 more
doaj   +1 more source

Association of clinical prediction scores with hospital mortality in an adult medical and surgical intensive care unit in Kenya

Frontiers in Medicine, 2023
ImportanceMortality prediction among critically ill patients in resource limited settings is difficult. Identifying the best mortality prediction tool is important for counseling patients and families, benchmarking quality improvement efforts, and ...
B. Jason Brotherton, B. Jason Brotherton, Mugdha Joshi, George Otieno, Sarah Wandia, Hannah Gitura, Ariel Mueller, Tony Nguyen, Steve Letchford, Elisabeth D. Riviello, Evelyn Karanja, Kristina E. Rudd   +11 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Biological plausibility for interactions between dietary fat, resveratrol, ACE2, and SARS-CoV illness severity

American Journal of Physiology. Endocrinology and Metabolism, 2020
The angiotensin converting enzyme-2 (ACE2) cellular receptor is responsible for the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), thus impacting the entrance and clearance of the virus.
Justine R. Horne, M. Vohl
semanticscholar   +1 more source

Disparity between General Symptom Relief and Remission Criteria in the Positive and Negative Syndrome Scale (PANSS): A Post-treatment Bifactor Item Response Theory Model. [PDF]

, 2017
Objective: Total scale scores derived by summing ratings from the 30-item PANSS are commonly used in clinical trial research to measure overall symptom severity, and percentage reductions in the total scores are sometimes used to document the efficacy of
Anderson, Ariana E, Bilder, Robert M, Han, Carol, Mansolf, Maxwell, Marder, Stephen R, Reise, Steven P   +5 more
core  

Explaining adherence to self-care behaviours amongst adolescents with food allergy: a comparison of the health belief model and the common sense self-regulation model [PDF]

, 2014
OBJECTIVES: To identify explanations for adherence to self-care behaviours amongst adolescents with food allergy-induced anaphylaxis using two social cognition models: the health belief model (HBM) and the common sense self-regulation model (CS-SRM).
Aiken, Ajzen, Bock, Bock, Box, Carpenter, Champion, DiMatteo, Gallagher, Gillibrand, Goldberg, Hagger, Henshaw, Kim, Knibb, Leventhal, Macadam, Meyer, Moss-Morris, Ogden, Pereira, Pumphrey, Pumphrey, Resuscitation Council (UK), Richards, Rogers, Rosenstock, Sampson, Sampson, Sutton, Sutton, Velde   +31 more
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Evaluation of Association Between the Severity of Temporomandibular Disorders and Quality of Sleep in a Selected Iranian Population

Frontiers in Dentistry, 2019
Objectives: Temporomandibular disorder (TMD), as a prevalent condition, has been reported to be related to changes in sleep quality. This study aims to assess the association between TMD severities and sleep quality in a selected Iranian population by ...
Abdolaziz Haghnegahdar, Aisa Zamani, Mehrdad Vossoughi   +2 more
doaj   +1 more source

An Artificial Neural Network Model for Pediatric Mortality Prediction in Two Tertiary Pediatric Intensive Care Units in South Africa. A Development Study

Frontiers in Pediatrics, 2022
ObjectivesThe performance of mortality prediction models remain a challenge in lower- and middle-income countries. We developed an artificial neural network (ANN) model for the prediction of mortality in two tertiary pediatric intensive care units (PICUs)
Michael A. Pienaar, Joseph B. Sempa, Nicolaas Luwes, Lincoln J. Solomon   +3 more
doaj   +1 more source

181 Evaluating the Association of Age with Acuity and Severity of Illness at Initial Clinical Presentation in Patients with Leukemia and Lymphoma [PDF]

, 2023
Tarun Jain, Xu Ji, Nicholas P. DeGroote, Cortland Coxhead, Ann C. Mertens, Sharon M. Castellino   +5 more
openalex   +1 more source