Results 71 to 80 of about 3,121,748 (378)

Possible role of human ribonuclease dicer in the regulation of R loops

FEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik, Paulina Krzeminska, Anna Kurzynska‐Kokorniak   +2 more
wiley   +1 more source

Impact of disease duration on functional status of patients with spinocerebellar ataxia type 2

Arquivos de Neuro-Psiquiatria
Objective: To correlate disease duration in spinocerebellar ataxia type 2 (SCA2) with disease severity, balance and functionality. Method: Sixteen SCA2 patients were analyzed for: disease duration, disease severity (SARA score), balance (Berg balance ...
Thiago R. Padilha Amarante, Sibele Y. M. Takeda, Hélio A. G. Teive, Marise Bueno Zonta   +3 more
doaj   +1 more source

Orthodontic treatment need in a group of 9-12-year-old Brazilian schoolchildren

Brazilian Oral Research, 2009
The present study aimed to evaluate the need for orthodontic treatment in Brazilian schoolchildren presenting both late mixed dentition and early permanent dentition as well as to determine the possible factors associated with this necessity.
Patricia Fernanda Dias, Rogerio Gleiser
doaj   +1 more source

Investigating the role of anticipatory reward and habit strength in obsessive-compulsive disorder [PDF]

, 2017
Aims: To determine the rates and associated illness characteristics of obsessive-compulsive disorder (OCD) patients who describe their symptoms as either rewarding or habitual.
Dawson, Andrew, Ferreira, Gabriela M, Fontenelle, Leonardo F, Lorenzetti, Valentina, Yucel, Murat   +4 more
core   +1 more source

FGF14 GAA Intronic Expansion in Unsolved Adult‐Onset Ataxia in the Care4Rare Canada Consortium

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Spinocerebellar ataxias (SCA) represent a clinically and genetically heterogeneous group of progressive neurodegenerative diseases with prominent cerebellar atrophy. Recently, a novel pathogenic repeat expansion in intron 1 of FGF14 was identified, causing adult‐onset SCA (SCA27B). We aimed to determine the proportion
Alexanne Cuillerier, Giulia F. Del Gobbo, Layla Mackay, Erika Wall, Madeline Couse, Laura M. McDonell, Mireille Cloutier, Matt C. Danzi, Jodi Warman‐Chardon, Pierre R. Bourque, Oksana Suchowersky, Alan Mears, Luke Seldenthuis, Wendy Mears, Laura Larrigan, Alexandre White‐Brown, Gerald Pfeffer, Dennis E. Bulman, David Dyment, Care4Rare Canada Consortium, Kym M. Boycott   +20 more
wiley   +1 more source

Value of proteinuria in evaluating the severity of HELLP and its maternal and neonatal outcomes

BMC Pregnancy and Childbirth, 2023
Background HELLP syndrome refers to a group of clinical syndromes characterized by hemolysis, elevated liver enzymes and low platelet, and the evidence on the association between proteinuria and the severity of HELLP and its maternal and neonatal ...
Yan Jiao, Yan Liu, Hongyuan Li, Zimeng Song, Shiliang Wang, Jiao Zhang, Jian Li, Jia Liu, Peng Wang, Yanhong Chen   +9 more
doaj   +1 more source

A study of sleep quality and quality of life in children with atopic dermatitis between 6 and 12 years of age

Indian Journal of Paediatric Dermatology, 2023
Introduction: Atopic dermatitis (AD) is a common, chronic, relapsing dermatitis, affecting mainly children. It is associated with intense pruritus which can disrupt the sleep and quality of life (QOL), thereby impairing the neurocognitive development. An
Febin Kallan, Rathish T Pillai, P T Hijaz, P S Simi, Rakhee V Nair   +4 more
doaj   +1 more source

How much does an interlibrary loan request cost? A review of the literature [PDF]

arXiv, 2020
Interlibrary loan (ILL) services are used to fill the gap between academic libraries' collections and the information needs of their users. Today's trend toward the cancellation of serials "Big Deals" has increased the importance of clear information around ILL to support decision-making. In order to plan the cancellation of a journal package, academic
arxiv  

Deaths certified as asthma and use of medical services: A national case-control study [PDF]

, 2005
This is an open access publication. The official published version can be accessed from the link below.Background: Studies have linked asthma death to either increased or decreased use of medical services.
Anderson, H, Ayres, J, Bland, J, Butland, B, Harrison, B, on, b, Peckitt, C, Sturdy, P, Victor, C   +8 more
core   +2 more sources

Music Interventions in Hyperacute and Acute Stroke Patients: A Randomized Controlled Pilot Feasibility Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Music interventions have been shown to have beneficial effects on hemodynamic parameters, pain, and anxiety in various medical settings. However, music interventions in the setting of acute stroke have not been studied. The objective of this trial was to perform a pilot feasibility study of music interventions in the setting of acute
Jeffrey J. Fletcher, Allison Edberg, Ronald Grifka, Joan Westendorp, Augusto Elias, Jacquie Knott, Elizabeth Martin, Fazeel Siddiqui   +7 more
wiley   +1 more source