Results 71 to 80 of about 85,306 (297)

Role of TREM1 in the sevoflurane‐induced inflammatory activation of microglia in vitro

open access: yesIbrain, EarlyView.
Perioperative neurocognitive disorders (PNDs) are one of the most common complications in perioperative patients, and neuroinflammatory reaction mediated by microglia plays a key role in their formation. Triggering receptor expressed on myeloid cells 1 (TREM1) is a key regulator of inflammation.
Chunchun Tang   +8 more
wiley   +1 more source

Cognitive Impairment and Endoplasmic Reticulum Stress Induced by Repeated Short-Term Sevoflurane Exposure in Early Life of Rats

open access: yesFrontiers in Psychiatry, 2018
Sevoflurane is one of the most commonly used volatile anaesthetics for children, but the safety of prolonged or repeated clinical use of sevoflurane in infants or children is controversial.
Fu-Yi Shen   +13 more
doaj   +1 more source

Cognitive function and delirium following sevoflurane or propofol anesthesia for valve replacement surgery: A multicenter randomized controlled trial [PDF]

open access: gold, 2022
Guangyou Duan   +9 more
openalex   +1 more source

Research progress on the depth of anesthesia monitoring based on the electroencephalogram

open access: yesIbrain, Volume 11, Issue 1, Page 32-43, Spring 2025.
Electroencephalogram (EEG) can noninvasive, continuous, and real‐time monitor the state of brain electrical activity, and the monitoring of EEG can reflect changes in the depth of anesthesia (DOA). The development of artificial intelligence can enable anesthesiologists to extract, analyze, and quantify DOA from complex EEG data.
Xiaolan He, Tingting Li, Xiao Wang
wiley   +1 more source

Activation of Parabrachial Nucleus Glutamatergic Neurons Accelerates Reanimation from Sevoflurane Anesthesia in Mice

open access: yesAnesthesiology, 2019
What We Already Know about This Topic The parabrachial nucleus is a brainstem region involved in arousal. Brain regions involved in arousal regulate anesthetic induction and emergence. What This Article Tells Us That Is New Using chemogenetic techniques,
Tian-xiao Wang   +6 more
semanticscholar   +1 more source

Overnight Monitoring After T&A for Children Ages 24–36 Months: Is It Always Necessary?

open access: yesThe Laryngoscope, EarlyView.
This study aims to identify whether all children < 3 years of age require overnight admission after tonsillectomy with or without adenoidectomy. We found that 98.7% of children who were off oxygen within 3 h after surgery never went back on oxygen during the entire monitoring period.
Tyler Van Heest   +4 more
wiley   +1 more source

Sevoflurane Increases Hippocampal Theta Oscillations and Impairs Memory Via TASK-3 Channels

open access: yesFrontiers in Pharmacology, 2021
Sevoflurane can induce memory impairment during clinical anesthesia; however, the underlying mechanisms are largely unknown. TASK-3 channels are one of the potential targets of sevoflurane.
Linlin Han   +9 more
doaj   +1 more source

Sevoflurane attenuates brain damage through inhibiting autophagy and apoptosis in cerebral ischemia-reperfusion rats

open access: yesMolecular Medicine Reports, 2019
The present study aimed to investigate the effects of sevoflurane post-conditioning in a rat brain cerebral ischemia-reperfusion (I/R) model and examine its possible mechanism.
Cun-Xian Shi   +6 more
semanticscholar   +1 more source

Efficient analysis of toxicity and mechanisms of isoflurane on postoperative delirium by network toxicology and molecular docking

open access: yesNeuroprotection, EarlyView.
Abstract Postoperative delirium (POD), a prevalent neurological complication in older surgical patients, adversely affects recovery. Isoflurane, a common inhalational anesthetic, exhibits neurotoxic potential, but its role in POD pathogenesis remains unclear.
Zhiming Dai   +3 more
wiley   +1 more source

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