Results 71 to 80 of about 82,704 (334)

Role of TREM1 in the sevoflurane‐induced inflammatory activation of microglia in vitro

open access: yesIbrain, EarlyView.
Perioperative neurocognitive disorders (PNDs) are one of the most common complications in perioperative patients, and neuroinflammatory reaction mediated by microglia plays a key role in their formation. Triggering receptor expressed on myeloid cells 1 (TREM1) is a key regulator of inflammation.
Chunchun Tang   +8 more
wiley   +1 more source

Direct evidence for inhibition of mitochondrial permeability transition pore opening by sevoflurane preconditioning in cardiomyocytes: comparison with cyclosporine A. [PDF]

open access: yes, 2012
To assess whether sevoflurane preconditioning is associated with inhibition of mitochondrial permeability transition pore (MPTP), the effects of sevoflurane were compared with those of cyclosporine A, a known inhibitor of MPTP opening.
Figueredo, Vincent M   +4 more
core   +2 more sources

Tavşanlarda Propofol-Sevofluran, Midazolam-Sevofluran ve Medetomidin-Ketamin-Sevofluran Anestezi Kombinasyonlarının Göz İçi Basıncına Etkileri

open access: yesKafkas Universitesi Veteriner Fakultesi Dergisi, 2020
Intraocular pressure (IOP) is dependent on equilibrium between the rate of formation and outflow humor aqueous in the eye. Determination of IOP is one of the most important points and a very useful parameter in ophthalmic surgery. The aim of this study was to compare the effects of propofol + sevoflurane, midazolam + sevoflurane, medetomidine ...
Erol, Muharrem   +4 more
openaire   +6 more sources

Research progress on the depth of anesthesia monitoring based on the electroencephalogram

open access: yesIbrain, Volume 11, Issue 1, Page 32-43, Spring 2025.
Electroencephalogram (EEG) can noninvasive, continuous, and real‐time monitor the state of brain electrical activity, and the monitoring of EEG can reflect changes in the depth of anesthesia (DOA). The development of artificial intelligence can enable anesthesiologists to extract, analyze, and quantify DOA from complex EEG data.
Xiaolan He, Tingting Li, Xiao Wang
wiley   +1 more source

5‐HT3 receptor antagonists for preventing postoperative nausea and vomiting after gynecological surgery: A systematic review and network meta‐analysis

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background Gynecological surgery is generally associated with a high risk of postoperative nausea and vomiting (PONV), for which a combination of antiemetic therapies is advised, but adherence to these protocols is often low. Given the current reality, a preferred 5‐HT3 receptor antagonist for preventing PONV as a result of gynecological ...
Hongxia Xu   +7 more
wiley   +1 more source

Unveiling the Therapeutic Potential of Atractylis aristata Batt. Aqueous Extract: Anti‐inflammatory, Antioxidant, Antibacterial, Sedative Activities & Phytochemical Profiling

open access: yesChemistryOpen, EarlyView.
This study evaluates the pharmacological properties of the aqueous extract of Atractylis aristata, focusing on its antioxidant, anti‐inflammatory, antibacterial, and sedative activities. Phytochemical analysis identifies bioactive compounds, while in vitro and in vivo tests demonstrate its therapeutic potential in addressing oxidative stress ...
Asma Abid   +14 more
wiley   +1 more source

Activation of Parabrachial Nucleus Glutamatergic Neurons Accelerates Reanimation from Sevoflurane Anesthesia in Mice

open access: yesAnesthesiology, 2019
What We Already Know about This Topic The parabrachial nucleus is a brainstem region involved in arousal. Brain regions involved in arousal regulate anesthetic induction and emergence. What This Article Tells Us That Is New Using chemogenetic techniques,
Tian-xiao Wang   +6 more
semanticscholar   +1 more source

Sevoflurane induces the inattention, cognitive impairment, and motor dysfunction by hypermethylation of retinoic acid receptor α in the medial prefrontal cortex of neonatal mice

open access: yesVIEW, EarlyView.
The mechanisms underlying neurodevelopmental toxicity induced by repeated exposure to general anesthesia in neonatal mice remain to be fully elucidated. In this study, neonatal mice were exposed to sevoflurane on postnatal days 6, 8, and 10. On postnatal day 30, the medial prefrontal cortex was collected for whole‐genome bisulfite sequencing and RNA ...
Yu Hou   +10 more
wiley   +1 more source

Acquired narcolepsy secondary to a presumptive hypothalamic hamartoma in a young German wirehaired pointer dog

open access: yesVeterinary Record Case Reports, EarlyView.
Abstract A 3‐year‐old, male, entire, German wirehaired pointer dog was presented with a 2‐year history of paroxysmal episodes of collapse associated with reduced levels of consciousness. A magnetic resonance imaging study identified a single, ill‐defined, non‐contrast‐enhancing, intra‐axial mass lesion involving the hypothalamus.
Callum Atkins   +3 more
wiley   +1 more source

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