Results 61 to 70 of about 60,245 (274)

mtDNA-cGAS-STING axis-dependent NLRP3 inflammasome activation contributes to postoperative cognitive dysfunction induced by sevoflurane in mice

International Journal on Biological Sciences
The activation of NLRP3 inflammasome in microglia is critical for neuroinflammation during postoperative cognitive dysfunction (POCD) induced by sevoflurane.
Nan-Shi-Yu Yang, W. Zhong, Han-Xi Sha, Chen-Yu Zhang, Ling Jin, J. Duan, Jian-Bing Xiong, Zhi-Jian You, Yong Zhou, C. Guan   +9 more
semanticscholar   +1 more source

The Influence of Pharmacological Preconditioning with Sevoflurane on Incidence of Early Allograft Dysfunction in Liver Transplant Recipients

Anesthesiology Research and Practice, 2012
Background. Pharmacological preconditioning is one of the tools used to diminish preservation injury. We investigated the influence of sevoflurane preconditioning of liver grafts on postoperative graft function. Methods.
Andrei F. Minou, Alexander M. Dzyadzko, Aliaksei E. Shcherba, Oleg O. Rummo   +3 more
doaj   +1 more source

Cerebrovascular reactivity to hypercapnia during sevoflurane or desflurane anesthesia in rats [PDF]

Korean Journal of Anesthesiology, 2019
Background Hypercapnia causes dilation of cerebral vessels and increases cerebral blood flow, resulting in increased intracranial pressure. Sevoflurane is reported to preserve cerebrovascular carbon dioxide reactivity.
Koji Sakata, Kazuhiro Kito, Naokazu Fukuoka, Kiyoshi Nagase, Kumiko Tanabe, Hiroki Iida   +5 more
doaj   +1 more source

Sevoflurane suppresses cell viability and invasion and promotes cell apoptosis in colon cancer by modulating exosome-mediated circ-HMGCS1 via the miR-34a-5p/SGPP1 axis

Oncology Report, 2020
As a novel halogenated hydroxyl ether-inhaled general anesthetic, sevoflurane has been reported to affect the progression of diverse human cancers. In the present study, we aimed to explore the functions and underlying mechanisms of sevoflurane in colon ...
Juan He, Huaping Zhao, Xing Liu, Dongmei Wang, Yong Wang, Yanqiu Ai, Jianjun Yang   +6 more
semanticscholar   +1 more source

An Exploratory Study of Sevoflurane as an Alternative for Difficult Sedation in Critically Ill Children* [PDF]

, 2018
El estudio exploró el uso del sevoflurano inhalado como una alternativa terapéutica en un grupo de niños críticamente enfermos con dificultades de sedación. Se evaluó la eficacia del sevoflurano en el control de la agitación, los efectos secundarios y la
Mencía Bartolomé, Santiago, Palacios, Alba, Miriam García, Alba Palacios, Blanca Toledo, García, Miriam, Ordóñez, Olga, Ana M. Llorente, Toledo, Blanca, Jesús López-Herce, López-Herce Cid, Jesús, Santiago Mencía, Llorente, Ana, Olga Ordóñez   +13 more
core   +1 more source

HSP90 inhibitor 17AAG attenuates sevoflurane-induced neurotoxicity in rats and human neuroglioma cells via induction of HSP70

Journal of Translational Medicine, 2020
Background 17AAG has been extensively studied for its antitumor effects that protect cells from lethal stress by maintaining protein stability. The role of 17AAG in sevoflurane-induced neuronal injury has never been studied.
Min Liu, Moyun Li, Yu Zhou, Qian Zhou, Yugang Jiang   +4 more
doaj   +1 more source

Autophagy Is Involved in the Sevoflurane Anesthesia-Induced Cognitive Dysfunction of Aged Rats. [PDF]

PLoS ONE, 2016
Autophagy is associated with regulation of both the survival and death of neurons, and has been linked to many neurodegenerative diseases. Postoperative cognitive dysfunction is commonly observed in elderly patients following anesthesia, but the ...
Xiaoming Zhang, Youfa Zhou, Mingmin Xu, Gang Chen   +3 more
doaj   +1 more source

Sevoflurane exposure may cause dysplasia of dendritic spines and result in fine motor dysfunction in developing mouse through the PI3K/AKT/mTOR pathway

Frontiers in Neuroscience, 2022
Sevoflurane has become one of the most widely used volatile anesthetics in pediatric surgery. However, sevoflurane exposure may interfere with dendritic development and synaptogenesis, resulting in brain function impairment.
Linhong Zhong, Xiaofan Ma, Yixuan Niu, Lei Zhang, Zhenyu Xue, Jia Yan, Hong Jiang   +6 more
doaj   +1 more source

The positive correlation between sevoflurane blood/gas partition coefficient and the volume of emulsified sevoflurane delivered. [PDF]

, 2020
The positive correlation between sevoflurane blood/gas partition coefficient and the volume of emulsified sevoflurane delivered.
Yao Li (154923), Peng Zhang (2071), Ting Xu (215531)   +2 more
core   +1 more source

Bumetanide attenuates sevoflurane‐induced neuroapoptosis in the developing dentate gyrus and impaired behavior in the contextual fear discrimination learning test

Brain and Behavior, 2022
Introduction Sevoflurane acts as a gamma‐aminobutyric acid subtype A receptor agonist and can induce widespread apoptosis of immature dentate granule cells in postnatal day 21 mice.
Kai Wei, Yiheng Liu, Xiamin Yang, Jin Liu, Yuan Li, Meng Deng, Yingwei Wang   +6 more
doaj   +1 more source