Results 51 to 60 of about 60,245 (274)

Mitophagy impairment is involved in sevoflurane-induced cognitive dysfunction in aged rats

Aging, 2020
Postoperative cognitive dysfunction (POCD) is frequently observed in elderly patients following anesthesia, but its pathophysiological mechanisms have not been fully elucidated.
Yeru Chen, Piao Zhang, Xianyi Lin, Huan-yi Zhang, Jiamin Miao, You-fa Zhou, Gang Chen   +6 more
semanticscholar   +1 more source

Sevoflurane Prevents Liver Inflammatory Response Induced by Lung Ischemia-Reperfusion [PDF]

, 2014
Background: Transplants cause ischemia-reperfusion (IR) injury that can affect distant organs. Liver is particularly sensitive to IR injury. The present randomized experimental study was designed to investigate a possible protective effect of sevoflurane
Isea, Jesús, Cusati, Gabriel, Erquicia, Iñaki, Cusati, G, Paredes Royano, Sergio Damián, García, C, Simón Adiego, Carlos María, Isea, J, Garutti Martínez, Ignacio, Rancán, Lisa, Vara Ameigeiras, Elena María, Huerta Martínez, Luis Javier, Erquicia, I, García Martín, M. Cruz   +13 more
core   +1 more source

Resveratrol Mitigates Sevoflurane-Induced Neurotoxicity by the SIRT1-Dependent Regulation of BDNF Expression in Developing Mice

Oxidative Medicine and Cellular Longevity, 2020
Various lines of evidence suggest that neonatal exposure to general anesthetics, especially repeatedly, results in neuropathological brain changes and long-term cognitive impairment.
Xiaole Tang, Yilin Zhao, Zhi-qiang Zhou, Jing Yan, Biyun Zhou, Xiaohui Chi, A. Luo, Shiyong Li   +7 more
semanticscholar   +1 more source

Speed of Recovery and Side-effect Profile of Sevoflurane Sedation Compared with Midazolam [PDF]

, 2001
Background Sedation for surgical procedures performed with regional or local anesthesia has usually been achieved with intravenous medications, whereas the use of volatile anesthetics has been limited.
Ghoneim, Mohamed M., Epstein, Richard H., Binstock, Wendy B., the Sevoflurane Sedation Study Group, Epstein, Richard, Kharasch, Evan D., Groudine, Scott B., Ibrahim, Andra E., Ebert, Thomas J., Philip, Beverly K.   +9 more
core   +1 more source

Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1)

Cancer Cell International, 2019
Background Ovarian cancer is one of the leading causes of female death worldwide, with a poor prognosis of advanced patients. Sevoflurane, a volatile anesthetic commonly used in clinical operations, has been reported to have anti-cancer activity against ...
Chuanfeng Zhang, Baosheng Wang, Xiuqin Wang, Xiugui Sheng, Yongchun Cui   +4 more
doaj   +1 more source

Sevoflurane anesthesia ameliorates LPS-induced acute lung injury (ALI) by modulating a novel LncRNA LINC00839/miR-223/NLRP3 axis

BMC Pulmonary Medicine, 2022
Background Sevoflurane is considered as a lung-protective factor in acute lung injury (ALI), but the underlying molecular mechanism remains largely unknown.
Zhiling Fu, Xiuying Wu, Fushuang Zheng, Yan Zhang   +3 more
doaj   +1 more source

Sevoflurane Therapy for Severe Refractory Bronchospasm in Children [PDF]

, 2016
Este artículo presenta una serie de casos clínicos que exploran el uso del sevoflurano en el tratamiento del broncoespasmo severo en niños. Aunque se trata de un estudio con limitaciones propias de este tipo de diseño, los resultados sugieren que el ...
Mencía Bartolomé, Santiago, Palacios, Alba, Alba Palacios, Blanca Toledo, Jaime Cruz, Jesus Lopez-Herce, Ana M. Llorente, Cruz, Jaime, Toledo, Blanca, Ordoñez, Olga, Marta Olmedilla, López-Herce Cid, Jesús, Santiago Mencía, Olmedilla, Marta, Llorente, Ana, Olga Ordóñez   +15 more
core   +1 more source

Impact of Sevoflurane and Thiopental Used Over the Course of Electroconvulsive Therapy: Propensity Score Matching Analysis

Frontiers in Human Neuroscience, 2022
ObjectiveAlthough anesthetics play an important role in electroconvulsive therapy (ECT), the clinical efficacy and seizure adequacy of sevoflurane in the course of ECT remain unclear.
Taisuke Yatomi, Takahito Uchida, Takahito Uchida, Akihiro Takamiya, Masataka Wada, Shun Kudo, Kazuki Nakajima, Hana Nishida, Bun Yamagata, Masaru Mimura, Jinichi Hirano   +10 more
doaj   +1 more source

Investigation of Genotoxic Effect of Desflurane and Sevoflurane on Periferic Lymphocyte with Comet Assay Method [PDF]

, 2016
Aim: There are several clinical and cytogenetic studies that anesthetics cause choromosomal changes. We report data on the possible genotoxic properties of two inhalational anaesthetics, sevoflurane and desflurane in lymphocytes of children evaluated for
Kendigelen, Pınar, Tütüncü, Ayşe Çiğdem, Çakmakkaya, Serpil, Serpil Çakmakkaya, Güner Kaya, Yeşim Işıkçı, IŞIKÇI, Yeşim, Kaya, Güner, Ayşe Çiğdem Tütüncü, Fatiş Altındaş, Altındaş, Fatiş, Pınar Kendigelen   +11 more
core   +1 more source

Sevoflurane postconditioning improves spatial learning and memory ability involving mitochondrial permeability transition pore in hemorrhagic shock and resuscitation rats

Brain and Behavior, 2020
Background Hemorrhagic shock induces the cognitive deficiency. Sevoflurane postconditioning has been documented to provide neuroprotection against ischemic–reperfusion injury by suppressing apoptosis.
Li Zhang, Li Huang, Jingxian Wang, Muchun Zhang, Ye Zhang, Xianwen Hu   +5 more
doaj   +1 more source