Results 31 to 40 of about 42,399 (237)

Sevoflurane postconditioning improves spatial learning and memory ability involving mitochondrial permeability transition pore in hemorrhagic shock and resuscitation rats

Brain and Behavior, 2020
Background Hemorrhagic shock induces the cognitive deficiency. Sevoflurane postconditioning has been documented to provide neuroprotection against ischemic–reperfusion injury by suppressing apoptosis.
Li Zhang, Li Huang, Jingxian Wang, Muchun Zhang, Ye Zhang, Xianwen Hu   +5 more
doaj   +1 more source

CP-FTMW spectrum of Sevoflurane

, 2023
<p>9.1 million averages of the CP-FTMW spectrum of sevoflurane</p ...
Steber, Amanda
core   +1 more source

HSP90 inhibitor 17AAG attenuates sevoflurane-induced neurotoxicity in rats and human neuroglioma cells via induction of HSP70

Journal of Translational Medicine, 2020
Background 17AAG has been extensively studied for its antitumor effects that protect cells from lethal stress by maintaining protein stability. The role of 17AAG in sevoflurane-induced neuronal injury has never been studied.
Min Liu, Moyun Li, Yu Zhou, Qian Zhou, Yugang Jiang   +4 more
doaj   +1 more source

Autophagy Is Involved in the Sevoflurane Anesthesia-Induced Cognitive Dysfunction of Aged Rats. [PDF]

PLoS ONE, 2016
Autophagy is associated with regulation of both the survival and death of neurons, and has been linked to many neurodegenerative diseases. Postoperative cognitive dysfunction is commonly observed in elderly patients following anesthesia, but the ...
Xiaoming Zhang, Youfa Zhou, Mingmin Xu, Gang Chen   +3 more
doaj   +1 more source

Photolabeling of Rap1 by using azi-sevoflurane.

, 2019
(A) Photolabeling experiment was performed using azi-sevoflurane. Sequences covered by mass spectrometry is highlighted in yellow. The adducted residue is shown in red. Red box denotes high conserved GTP-binding domain among Ras-related proteins.
Hasan Babazada (3666517), Koichi Yuki (398264), Nathan Blazon-Brown (6685262), Kirsten C. Odegard (6685265), Weiming Bu (184333), Renyu Liu (184348), Lifei Hou (613838), Sophia Koutsogiannaki (3666520), Hui Zha (6685259), Erika Matsunami (772446), Roderic G. Eckenhoff (160628)   +10 more
core   +1 more source

Minocycline Attenuates Sevoflurane-Induced Postoperative Cognitive Dysfunction in Aged Mice by Suppressing Hippocampal Apoptosis and the Notch Signaling Pathway-Mediated Neuroinflammation

Brain Sciences, 2023
Postoperative cognitive dysfunction (POCD), an important postoperative neurological complication, is very common and has an elevated incidence in elderly patients.
Junjie Liang, Shanshan Han, Chao Ye, Haimeng Zhu, Jiajun Wu, Yunjuan Nie, Gaoshang Chai, Peng Zhao, Dengxin Zhang   +8 more
doaj   +1 more source

Bumetanide attenuates sevoflurane‐induced neuroapoptosis in the developing dentate gyrus and impaired behavior in the contextual fear discrimination learning test

Brain and Behavior, 2022
Introduction Sevoflurane acts as a gamma‐aminobutyric acid subtype A receptor agonist and can induce widespread apoptosis of immature dentate granule cells in postnatal day 21 mice.
Kai Wei, Yiheng Liu, Xiamin Yang, Jin Liu, Yuan Li, Meng Deng, Yingwei Wang   +6 more
doaj   +1 more source

Sevoflurane exposure may cause dysplasia of dendritic spines and result in fine motor dysfunction in developing mouse through the PI3K/AKT/mTOR pathway

Frontiers in Neuroscience, 2022
Sevoflurane has become one of the most widely used volatile anesthetics in pediatric surgery. However, sevoflurane exposure may interfere with dendritic development and synaptogenesis, resulting in brain function impairment.
Linhong Zhong, Xiaofan Ma, Yixuan Niu, Lei Zhang, Zhenyu Xue, Jia Yan, Hong Jiang   +6 more
doaj   +1 more source

Therapeutic effects of intravenous administration of bone marrow stromal cells on sevoflurane-induced neuronal apoptosis and neuroinflammation in neonatal rats [PDF]

Korean Journal of Anesthesiology, 2015
BackgroundSevoflurane exposure during the early postnatal period causes neuroinflammation and neuronal apoptosis in rodents. Bone marrow stromal cells (BMSCs) have been shown to protect and repair the damaged central nervous system, for example in ...
ZhongLiang Sun, Maiko Satomoto, Koshi Makita   +2 more
doaj   +1 more source

Animal stroke models and outcome evaluation: A review

Animal Models and Experimental Medicine, EarlyView.
Rodents are the preeminent stroke model species. Large animal models exist too, but are poorly standardized. Ischemic and hemorrhagic experimental models are available, with the intraluminal filament model being predominant. Outcomes are evaluated via quantifying subjects' sensorimotor impairment, cognitive memory faculties, degree of cellular ...
Solsa Cariba, Helen M. Atkinson, Anthony K. C. Chan   +2 more
wiley   +1 more source