Results 31 to 40 of about 37,501 (234)

The effects of midazolam and sevoflurane on the GABA receptors with alternatively spliced variants of the γ2 subunit [PDF]

Korean Journal of Anesthesiology, 2011
BackgroundEmergence agitation after sevoflurane anesthesia in children can be prevented by midazolam. Alternative splicing of the GABAA receptor changes with age.
Woosik Eom, Jung Min Lee, Jeongmi Park, Kyungho Choi, Sung-Jun Jung, Hee-Soo Kim   +5 more
doaj   +1 more source

Mild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation [PDF]

, 2010
Introduction: Hypothermia improves survival and neurological recovery after cardiac arrest. Pro-inflammatory cytokines have been implicated in focal cerebral ischemia/reperfusion in-jury.
Meybohm, Patrick, Zitta, Karina, Grünewald, Matthias Lars, Albrecht, Martin, Zacharowski, Kai, Lucius, Ralph, Hensler, Johannes, Bein, Berthold, Fösel, Nikola   +8 more
core   +1 more source

Neuroprotective effects of sevoflurane against electromagnetic pulse-induced brain injury through inhibition of neuronal oxidative stress and apoptosis. [PDF]

PLoS ONE, 2014
Electromagnetic pulse (EMP) causes central nervous system damage and neurobehavioral disorders, and sevoflurane protects the brain from ischemic injury. We investigated the effects of sevoflurane on EMP-induced brain injury.
Bin Deng, Hao Xu, Jin Zhang, Jin Wang, Li-Chun Han, Li-Ya Li, Guang-Li Wu, Yan-Ning Hou, Guo-Zhen Guo, Qiang Wang, Han-Fei Sang, Li-Xian Xu   +11 more
doaj   +1 more source

PEX5R/Trip8b-HCN2 channel regulating neuroinflammation involved in perioperative neurocognitive disorders

Cell & Bioscience, 2022
Background Clinical and animal studies demonstrated that neuroinflammation from anesthesia (sevoflurane) is the main contributor to cause perioperative neurocognitive disorders (PND).
Feng Xu, Yafeng Wang, Linlin Han, Daling Deng, Yuanyuan Ding, LuLin Ma, Qingtong Zhang, Xiangdong Chen   +7 more
doaj   +1 more source

Influence of the sevoflurane concentration on the occurrence of epileptiform EEG patterns.

PLoS ONE, 2014
Objectives and aimThis study was performed to analyse the effects of different sevoflurane concentrations on the incidence of epileptiform EEG activity during induction of anaesthesia in children in the clinical routine.BackgroundIt was suggested in the ...
Ines Kreuzer, W Alexander Osthaus, Arthur Schultz, Barbara Schultz   +3 more
doaj   +1 more source

Sevoflurane anesthesia ameliorates LPS-induced acute lung injury (ALI) by modulating a novel LncRNA LINC00839/miR-223/NLRP3 axis

BMC Pulmonary Medicine, 2022
Background Sevoflurane is considered as a lung-protective factor in acute lung injury (ALI), but the underlying molecular mechanism remains largely unknown.
Zhiling Fu, Xiuying Wu, Fushuang Zheng, Yan Zhang   +3 more
doaj   +1 more source

Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1)

Cancer Cell International, 2019
Background Ovarian cancer is one of the leading causes of female death worldwide, with a poor prognosis of advanced patients. Sevoflurane, a volatile anesthetic commonly used in clinical operations, has been reported to have anti-cancer activity against ...
Chuanfeng Zhang, Baosheng Wang, Xiuqin Wang, Xiugui Sheng, Yongchun Cui   +4 more
doaj   +1 more source

Impact of Sevoflurane and Thiopental Used Over the Course of Electroconvulsive Therapy: Propensity Score Matching Analysis

Frontiers in Human Neuroscience, 2022
ObjectiveAlthough anesthetics play an important role in electroconvulsive therapy (ECT), the clinical efficacy and seizure adequacy of sevoflurane in the course of ECT remain unclear.
Taisuke Yatomi, Takahito Uchida, Takahito Uchida, Akihiro Takamiya, Masataka Wada, Shun Kudo, Kazuki Nakajima, Hana Nishida, Bun Yamagata, Masaru Mimura, Jinichi Hirano   +10 more
doaj   +1 more source

Minocycline Attenuates Sevoflurane-Induced Postoperative Cognitive Dysfunction in Aged Mice by Suppressing Hippocampal Apoptosis and the Notch Signaling Pathway-Mediated Neuroinflammation

Brain Sciences, 2023
Postoperative cognitive dysfunction (POCD), an important postoperative neurological complication, is very common and has an elevated incidence in elderly patients.
Junjie Liang, Shanshan Han, Chao Ye, Haimeng Zhu, Jiajun Wu, Yunjuan Nie, Gaoshang Chai, Peng Zhao, Dengxin Zhang   +8 more
doaj   +1 more source

Sevoflurane postconditioning improves spatial learning and memory ability involving mitochondrial permeability transition pore in hemorrhagic shock and resuscitation rats

Brain and Behavior, 2020
Background Hemorrhagic shock induces the cognitive deficiency. Sevoflurane postconditioning has been documented to provide neuroprotection against ischemic–reperfusion injury by suppressing apoptosis.
Li Zhang, Li Huang, Jingxian Wang, Muchun Zhang, Ye Zhang, Xianwen Hu   +5 more
doaj   +1 more source