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Differential effects of sevoflurane on the growth and apoptosis of human cancer cell lines [PDF]
, 2020 Purpose: There have been contradictory findings regarding the effects of sevoflurane on the oncogenic properties of cancer cells. This study was conducted to gain insights into the fundamental rules governing the differential effects of sevoflurane ...
Hirai, Takahiro +5 more
core +1 more source
British Journal of Anaesthesia, 1996 Sevoflurane is a fluoridated derivative of methyl isopropyl ether. Its administration does not require the use of sophisticated vaporizers and its blood/gas partition coefficient is 0.69. Sevoflurane is the only ethereal anesthesia that does not trigger a reflex response or cause airway irritation during inhaled induction.
F, Gilsanz +3 more
openaire +4 more sources
The Effect of Sevoflurane Plus Propofol on Pain and Complications after Laminectomy: A Randomized Double Blind Clinical Trial [PDF]
Journal of Clinical and Diagnostic Research, 2017 Introduction: Pain is one of the most important reasons for the patients concern after surgery. The perfect sedative should have properties like rapid onset, least pain and adverse effects.
Aminolah Vasigh +4 more
doaj +1 more source
Sevoflurane posttreatment prevents oxidative and inflammatory injury in ventilator-induced lung injury. [PDF]
PLoS ONE, 2018 Mechanical ventilation is a life-saving clinical treatment but it can induce or aggravate lung injury. New therapeutic strategies, aimed at reducing the negative effects of mechanical ventilation such as excessive production of reactive oxygen species ...
Julie Wagner +7 more
doaj +1 more source
Mediators of Inflammation, 2020 To investigate the mechanism dexmedetomidine in relieving the neurotoxicity of a developing brain induced by sevoflurane. Sprague-Dawley rats, 6 days old, were randomly divided into three groups.
Yunxia Dong +5 more
doaj +1 more source
miRNA‐384‐3p alleviates sevoflurane‐induced nerve injury by inhibiting Aak1 kinase in neonatal rats
Brain and Behavior, 2022 Objective Sevoflurane is a common anesthetic and is widely used in pediatric clinical surgery to induce and maintain anesthesia through inhalation. Increasing studies have revealed that sevoflurane has neurotoxic effects on neurons, apoptosis, and memory
Yuanyuan Chen, Xuan Gao, Hao Pei
doaj +1 more source
Journal of Pharmacological Sciences, 2021 Objective: To investigate the effect of sevoflurane on inflammation of microglia in hippocampus of neonatal rats, and to investigate whether the related mechanism is related to Wnt/β-Catenin/CaMKIV pathway. Methods: Neonatal rats were anesthetized with 2%
Fengjuan Wang +3 more
doaj +1 more source
Mechanisms of the beneficial effect of sevoflurane in liver ischemia/reperfusion injury [PDF]
Acta Cirúrgica Brasileira, 2015 PURPOSE: To evaluate the underlying mechanisms by which sevoflurane protects the liver against ischemia/reperfusion injury evaluate the mechanism by which sevoflurane exerts this protective effect.
Fernanda Paula Cavalcante +7 more
doaj +2 more sources
Comparison of emergence agitation between sevoflurane/nitrous oxide administration and sevoflurane administration alone in children undergoing adenotonsillectomy with preemptive ketorolac [PDF]
Korean Journal of Anesthesiology, 2014 BackgroundSevoflurane anesthesia commonly causes emergence agitation (EA) in children. One previous study has reported that the use of nitrous oxide (N2O) during the washout of sevoflurane may reduce EA by decreasing the residual sevoflurane ...
Ji Hye Park +6 more
doaj +1 more source
Sevoflurane and cardioprotection [PDF]
British Journal of Anaesthesia, 2008 The authors hypothesize that the cardioprotective effect of sevoflurane administered throughout CABG operation may be time- and dose-dependent.
L. Siracusano +3 more
openaire +3 more sources