Folia NeuropathologicaSevoflurane is an inhalation anaesthetic agent widely used in clinical settings. Despite good surgical outcomes using sevoflurane, patients frequently develop postoperative cognitive dysfunction (POCD).
Wenfeng Gao +5 more
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Differential effects of sevoflurane on the growth and apoptosis of human cancer cell lines [PDF]
, 2020 Purpose: There have been contradictory findings regarding the effects of sevoflurane on the oncogenic properties of cancer cells. This study was conducted to gain insights into the fundamental rules governing the differential effects of sevoflurane ...
Hirai, Takahiro +5 more
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Mediators of Inflammation, 2020 To investigate the mechanism dexmedetomidine in relieving the neurotoxicity of a developing brain induced by sevoflurane. Sprague-Dawley rats, 6 days old, were randomly divided into three groups.
Yunxia Dong +5 more
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Comparison of emergence agitation between sevoflurane/nitrous oxide administration and sevoflurane administration alone in children undergoing adenotonsillectomy with preemptive ketorolac [PDF]
Korean Journal of Anesthesiology, 2014 BackgroundSevoflurane anesthesia commonly causes emergence agitation (EA) in children. One previous study has reported that the use of nitrous oxide (N2O) during the washout of sevoflurane may reduce EA by decreasing the residual sevoflurane ...
Ji Hye Park +6 more
doaj +1 more source
Journal of Pharmacological Sciences, 2021 Objective: To investigate the effect of sevoflurane on inflammation of microglia in hippocampus of neonatal rats, and to investigate whether the related mechanism is related to Wnt/β-Catenin/CaMKIV pathway. Methods: Neonatal rats were anesthetized with 2%
Fengjuan Wang +3 more
doaj +1 more source
Mechanisms of the beneficial effect of sevoflurane in liver ischemia/reperfusion injury [PDF]
Acta Cirúrgica Brasileira, 2015 PURPOSE: To evaluate the underlying mechanisms by which sevoflurane protects the liver against ischemia/reperfusion injury evaluate the mechanism by which sevoflurane exerts this protective effect.
Fernanda Paula Cavalcante +7 more
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The effects of midazolam and sevoflurane on the GABA receptors with alternatively spliced variants of the γ2 subunit [PDF]
Korean Journal of Anesthesiology, 2011 BackgroundEmergence agitation after sevoflurane anesthesia in children can be prevented by midazolam. Alternative splicing of the GABAA receptor changes with age.
Woosik Eom +5 more
doaj +1 more source
Mild hypothermia alone or in combination with anesthetic post-conditioning reduces expression of inflammatory cytokines in the cerebral cortex of pigs after cardiopulmonary resuscitation [PDF]
, 2010 Introduction: Hypothermia improves survival and neurological recovery after cardiac arrest. Pro-inflammatory cytokines have been implicated in focal cerebral ischemia/reperfusion in-jury.
Meybohm, Patrick +8 more
core +1 more source
Neuroprotective effects of sevoflurane against electromagnetic pulse-induced brain injury through inhibition of neuronal oxidative stress and apoptosis. [PDF]
PLoS ONE, 2014 Electromagnetic pulse (EMP) causes central nervous system damage and neurobehavioral disorders, and sevoflurane protects the brain from ischemic injury. We investigated the effects of sevoflurane on EMP-induced brain injury.
Bin Deng +11 more
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Cell & Bioscience, 2022 Background Clinical and animal studies demonstrated that neuroinflammation from anesthesia (sevoflurane) is the main contributor to cause perioperative neurocognitive disorders (PND).
Feng Xu +7 more
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