Results 81 to 90 of about 85,306 (297)

Pathological fracture secondary to an aneurysmal bone cyst in the proximal femur of a 5‐year‐old French bulldog

Veterinary Record Case Reports, EarlyView.
Abstract A 5‐year‐old, male, neutered French bulldog was referred with a 24‐hour history of left hindlimb lameness. The patient presented with a 9/10 grade left pelvic limb lameness and pain on full extension of the left hip joint. Radiographs, computed tomography and ultrasound‐guided fine needle aspirates were performed, leading to a presumptive ...
Carolyn Averil Hylton, Oliver Anderson, Alejandro Suarez‐Bonnet, Simon L. Priestnall, Richard Meeson   +4 more
wiley   +1 more source

Intravenous methadone for pain management in cardiac surgery: a randomised controlled trial with plasma concentration analysis*

Anaesthesia, EarlyView.
Summary Introduction Postoperative pain after cardiac surgery remains significant despite the administration of opioids. Methadone may improve pain control and decrease the need for postoperative opioids. Randomised controlled trials, however, are limited and the effects of cardiopulmonary bypass on methadone pharmacokinetics are unclear.
Henry Man Kin Wong, Veronica Ka Wai Lai, Sandra Lok Ching Chiu, Wai Tat Wong, Siu Kwan Wo, Joan Zhong Zuo, Xiaodong Liu, Randolph Hung Leung Wong, Kwok Ming Ho   +8 more
wiley   +1 more source

Increased NMDA receptor inhibition at an increased Sevoflurane MAC

BMC Anesthesiology, 2012
Background Sevoflurane potently enhances glycine receptor currents and more modestly decreases NMDA receptor currents, each of which may contribute to immobility.
Brosnan Robert J, Thiesen Roberto
doaj   +1 more source

Effect of peri‐operative pharmacological interventions on postoperative delirium in patients having cardiac surgery: a systematic review and Bayesian network meta‐analysis

Anaesthesia, EarlyView.
Summary Introduction Postoperative delirium is a common complication following cardiac surgery. Despite its known impact on patient outcomes, effective preventative strategies remain elusive. We aimed to perform a comprehensive Bayesian network meta‐analysis of randomised controlled trials assessing the effect of pharmacological interventions on the ...
Ivo Queiroz, Lucas M. Barbosa, Mariano Gallo Ruelas, Beatriz Araújo, Maria L. R. Defante, Arthur H. Tavares, Cynthia Florencio de Mesquita, Tulio Pimentel, Beatriz Ximenes Mendes, Iuri Ferreira Felix, André Rivera, Rafael Oliva Morgado Ferreira, Helen M. de Oliveira, Bruno B. Righetto, Nathan J. Smischney, Guangyu Tong, Daqing Ma   +16 more
wiley   +1 more source

Accurate molecular imaging of small animals taking into account animal models, handling, anaesthesia, quality control and imaging system performance [PDF]

, 2015
Small-animal imaging has become an important technique for the development of new radiotracers, drugs and therapies. Many laboratories have now a combination of different small-animal imaging systems, which are being used by biologists, pharmacists ...
Bankstahl, Jens, Belcari, Nicola, Krämer, Stefanie, Vandenberghe, Stefaan, Vanhove, Christian, Visser, Eric   +5 more
core   +1 more source

Dexmedetomidine suppresses sevoflurane anesthesia-induced neuroinflammation through activation of the PI3K/Akt/mTOR pathway

BMC Anesthesiology, 2019
BackgroundSevoflurane, an inhalational general anesthetic, has become one of the most widely used inhalational anesthetics in surgery. However, previous studies have found that sevoflurane anesthesia can trigger an inflammatory response, resulting in ...
Nan Wang, Mingyu Wang
semanticscholar   +1 more source

Postoperative sore throat: a systematic review*

Anaesthesia, EarlyView.
Summary Introduction Postoperative sore throat is a common complaint with an incidence of up to 62%. While anaesthetists often perceive this as a minor and self‐limiting complication, postoperative sore throat is one of the leading causes of postoperative anaesthesia‐related discomfort.
Zachary J. Moulder, Jason Mann, Paul Bramley, Jana Heinz, Matthew D. Wiles   +4 more
wiley   +1 more source

Sugammadex-Enhanced Neuronal Apoptosis following Neonatal Sevoflurane Exposure in Mice

Anesthesiology Research and Practice, 2016
In rodents, neonatal sevoflurane exposure induces neonatal apoptosis in the brain and results in learning deficits. Sugammadex is a new selective neuromuscular blockade (NMB) binding agent that anesthesiologists can use to achieve immediate reversal of ...
Maiko Satomoto, Zhongliang Sun, Yushi U. Adachi, Koshi Makita   +3 more
doaj   +1 more source

Cistanches alleviates sevoflurane‐induced cognitive dysfunction by regulating PPAR‐γ‐dependent antioxidant and anti‐inflammatory in rats

Journal of Cellular and Molecular Medicine, 2019
This study aimed to investigate the protective effects and underlying mechanisms of cistanche on sevoflurane‐induced aged cognitive dysfunction rat model.
Sheng Peng, Pengyi Li, Peirong Liu, Hongzhu Yan, Juan Wang, Weihua Lu, Chunliang Liu, Yi-Ren Zhou   +7 more
semanticscholar   +1 more source

Optimizing Donor Kidneys During Normothermic Machine Perfusion With Sevoflurane: Design of a Research Model

Artificial Organs, EarlyView.
A stable kidney normothermic machine perfusion model with sevoflurane delivery via a vaporizer was established, enabling mechanistic and therapeutic studies of ischemia–reperfusion injury. ABSTRACT Normothermic machine perfusion (NMP) of donor kidneys provides an opportunity not only for organ preservation but also for therapeutic intervention to ...
Philip N. Günkel, Shuqi Yang, Rozemarijn S. Tuinhout, Sebastiaan J. Luttik, Roland F. Hoffmann, Petra J. Ottens, Damien Richard, Matthieu Jabaudon, Michel M. R. F. Struys, Henri G. D. Leuvenink, Gertrude J. Nieuwenhuijs‐Moeke   +10 more
wiley   +1 more source