Polymorphisms in the Promoter Region of the Chinese Bovine Gene [PDF]
The peroxisome proliferator-activated receptor gamma coactivator-1 alpha protein, encoded by the PPARGC1A gene, plays an important role in energy homeostasis.
M. J. Li +6 more
doaj +1 more source
Mapping and Validation of the Major Sex-Determining Region in Nile Tilapia (Oreochromis niloticus L.) Using RAD Sequencing [PDF]
Sex in Oreochromis niloticus (Nile tilapia) is principally determined by an XX/XY locus but other genetic and environmental factors also influence sex ratio.
McAndrew Brendan J. +31 more
core +1 more source
It has been presented the role of long non-coding RNAs (lncRNAs) in cervical cancer (CC). We aim to discuss the effect of sex-determining region Y-box 2 (SOX2)/lncRNA colon cancer-associated transcript-1 (CCAT1)/microRNA-185-3p (miR-185-3p)/forkhead box ...
Li Zhang +3 more
doaj +1 more source
Thimet oligopeptidase expression is differentially regulated in neuroendocrine and spermatid cell lines by transcription factor binding to SRY (sex-determining region Y), CAAT and CREB (cAMP-response-element-binding protein) promoter consensus sequences [PDF]
The zinc metalloprotease thimet oligopeptidase (EP24.15) is found predominantly in the neuroendocrine–gonadal axis where it is implicated in the processing of bioactive peptides, including GnRH (gonadotropin-releasing hormone), β-neoendorphin, α-neoendorphin and dynorphin(1–8), the progression of spermatogenesis and the normal clearance of β-amyloid in
Morrison, Lesley S., Pierotti, Adrian R.
openaire +2 more sources
FGF9 and WNT4 act as antagonistic signals to regulate mammalian sex determination [PDF]
The genes encoding members of the wingless-related MMTV integration site (WNT) and fibroblast growth factor (FGF) families coordinate growth, morphogenesis, and differentiation in many fields of cells during development.
Robin Lovell-Badge +41 more
core +1 more source
Downregulation of long non‐coding
Several studies have shown an important role for long non‐coding RNA (lncRNA) in breast cancer progression. The present study investigated the role of lncRNA Opa interacting protein 5‐antisense RNA 1 (OIP5‐AS1) in the progression of breast cancer. OIP5‐AS1 was significantly upregulated in breast cancer tissues and in breast cancer cell lines, and OIP5 ...
Huijuan Zeng +9 more
openaire +2 more sources
The multicopy gene Sly represses the sex chromosomes in the male mouse germline after meiosis. [PDF]
Studies of mice with Y chromosome long arm deficiencies suggest that the male-specific region (MSYq) encodes information required for sperm differentiation and postmeiotic sex chromatin repression (PSCR).
Yamauchi, Yasuhiro +13 more
core +1 more source
Why women see differently from the way men see? A review of sex differences in cognition and sports
The differences of learning and memory between males and females have been well documented and confirmed by both human and animal studies. The sex differences in cognition started from early stage of neuronal development and last through entire lifespan.
Rena Li
doaj +1 more source
Abnormal Sex Chromosome Constitution and Longitudinal Growth: Serum Levels of Insulin-Like Growth Factor (IGF)-I, IGF Binding Protein-3, Luteinizing Hormone, and Testosterone in 109 Males with 47,XXY, 47,XYY, or Sex-Determining Region of the Y Chromosome (SRY)-Positive 46,XX Karyotypes [PDF]
Abstract Context: Growth is a highly complex process regulated by the interaction between sex steroids and the GH IGF-axis. However, other factors such as sex chromosome-related genes play independent roles. Aim: The aim of the study was to evaluate the role of abnormal chromosome constitution for longitudinal growth in ...
Aksglaede, Lise +2 more
openaire +3 more sources
Sex determining region Y-box 2 (SOX2) amplification is an independent indicator of disease recurrence in sinonasal cancer. [PDF]
The transcription factor SOX2 (3q26.3-q27) is an embryonic stem cell factor contributing to the induction of pluripotency in terminally differentiated somatic cells.
Friedrich Bootz +29 more
core +1 more source

