Results 1 to 10 of about 31,435,271 (262)

X chromosome dosage and presence of SRY shape sex-specific differences in DNA methylation at an autosomal region in human cells [PDF]

Biology of Sex Differences, 2018
Background Sexual dimorphism in DNA methylation levels is a recurrent epigenetic feature in different human cell types and has been implicated in predisposition to disease, such as psychiatric and autoimmune disorders. To elucidate the genetic origins of
Bianca Ho, Keelin Greenlaw, Abeer Al Tuwaijri, Sanny Moussette, Francisco Martínez, Elisa Giorgio, Alfredo Brusco, Giovanni Battista Ferrero, Natália D. Linhares, Eugênia R. Valadares, Marta Svartman, Vera M. Kalscheuer, Germán Rodríguez Criado, Catherine Laprise, Celia M. T. Greenwood, Anna K. Naumova   +15 more
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A chromosome-level genome assembly of Hong Kong catfish (Clarias fuscus) uncovers a sex-determining region

BMC Genomics, 2023
Background Hong Kong catfish (Clarias fuscus) is an ecologically and economically important species that is widely distributed in freshwater regions of southern China. Hong Kong catfish has significant sexual growth dimorphism. The genome assembly of the
Chang-Xu Tian, Xing-Hua Lin, Da-Yan Zhou, Yu Chen, Yi-Jun Shen, Ming-Hui Ye, Cun-Yu Duan, Yu-Lei Zhang, Bin-Lan Yang, Si-Ping Deng, Chun-Hua Zhu, Guang-Li Li   +11 more
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An Infertile Azoospermic Male With 45, X T(Yp;15) Karyotype

Journal of Family and Reproductive Health, 2021
Objective: 45, X is a very rare condition that usually results from Y/autosomal translocations or insertions. Here we present an infertile azoospermic man who had 45, X t(Yp;15) karyotype and deletion of AZF (azoospermia factor) gene region. Case report:
Maryam Abiri, Maryam Hassanlou, Nima Narimani, Marzieh Zamani, Zahra Moeini   +4 more
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Determination of Sperm Sex Ratio in Bovine Semen Using Multiplex Real-time Polymerase Chain Reaction [PDF]

Asian-Australasian Journal of Animal Sciences, 2014
Gender selection is important in livestock industries; for example, female calves are required in the dairy industry. Sex-sorted semen is commonly used for the production of calves of the desired gender. However, assessment of the sex ratio of the sorted
Trisadee Khamlor, Petai Pongpiachan, Siwat Sangsritavong, Nipa Chokesajjawatee   +3 more
doaj   +1 more source

A Tandem Duplicate of Anti-Müllerian Hormone with a Missense SNP on the Y Chromosome Is Essential for Male Sex Determination in Nile Tilapia, Oreochromis niloticus. [PDF]

PLoS Genetics, 2015
Variation in the TGF-β signaling pathway is emerging as an important mechanism by which gonadal sex determination is controlled in teleosts. Here we show that amhy, a Y-specific duplicate of the anti-Müllerian hormone (amh) gene, induces male sex ...
Minghui Li, Yunlv Sun, Jiue Zhao, Hongjuan Shi, Sheng Zeng, Kai Ye, Dongneng Jiang, Linyan Zhou, Lina Sun, Wenjing Tao, Yoshitaka Nagahama, Thomas D Kocher, Deshou Wang   +12 more
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Phenotype expansion of variants affecting p38 MAPK signaling in hypospadias patients

Orphanet Journal of Rare Diseases, 2022
Background Hypospadias is a congenital anomaly of the male urogenital system. Genetics factors play an important role in its pathogenesis. To search for potential causal genes/variants for hypospadias, we performed exome sequencing in a pedigree with ...
Defu Lin, Huakang Du, Sen Zhao, Bowen Liu, Hongcheng Song, Guannan Wang, Weiping Zhang, Haiyan Liang, Pei Liu, Chao Liu, Wenwen Han, Zhenwu Li, Yang Yang, Shuofan Chen, Lina Zhao, Xiaoxin Li, Zhihong Wu, DISCO (Deciphering Disorders Involving Scoliosis & COmorbidities) study group, Ning Sun, Nan Wu   +19 more
doaj   +1 more source

Polymorphisms in the Promoter Region of the Chinese Bovine Gene [PDF]

Asian-Australasian Journal of Animal Sciences, 2013
The peroxisome proliferator-activated receptor gamma coactivator-1 alpha protein, encoded by the PPARGC1A gene, plays an important role in energy homeostasis.
M. J. Li, M. Liu, D. Liu, X. Y. Lan, C. Z. Lei, D. Y. Yang, H. Chen   +6 more
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SOX2 Regulates lncRNA CCAT1/MicroRNA-185-3p/FOXP3 Axis to Affect the Proliferation and Self-Renewal of Cervical Cancer Stem Cells

Nanoscale Research Letters, 2021
It has been presented the role of long non-coding RNAs (lncRNAs) in cervical cancer (CC). We aim to discuss the effect of sex-determining region Y-box 2 (SOX2)/lncRNA colon cancer-associated transcript-1 (CCAT1)/microRNA-185-3p (miR-185-3p)/forkhead box ...
Li Zhang, Chunjie Guo, Tiefeng Ji, Xin Chen   +3 more
doaj   +1 more source

Why women see differently from the way men see? A review of sex differences in cognition and sports

Journal of Sport and Health Science, 2014
The differences of learning and memory between males and females have been well documented and confirmed by both human and animal studies. The sex differences in cognition started from early stage of neuronal development and last through entire lifespan.
Rena Li
doaj   +1 more source

Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination.

PLoS Biology, 2009
Sex determination in mammals is controlled by the presence or absence of the Y-linked gene SRY. In the developing male (XY) gonad, sex-determining region of the Y (SRY) protein acts to up-regulate expression of the related gene, SOX9, a transcriptional ...
Debora Bogani, Pam Siggers, Rachel Brixey, Nick Warr, Sarah Beddow, Jessica Edwards, Debbie Williams, Dagmar Wilhelm, Peter Koopman, Richard A Flavell, Hongbo Chi, Harry Ostrer, Sara Wells, Michael Cheeseman, Andy Greenfield   +14 more
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