Results 41 to 50 of about 29,265,468 (278)

The human RPS4 paralogue on Yq11.223 encodes a structurally conserved ribosomal protein and is preferentially expressed during spermatogenesis. [PDF]

, 2010
BACKGROUND: The Y chromosome of mammals is particularly prone to accumulate genes related to male fertility. However, the high rate of molecular evolution on this chromosome predicts reduced power to the across-species comparative approach in identifying
Ricardo N Miguel, Nabeel A Affara, Ellis, Peter J.I., Lopes, Alexandra M., Sargent, Carole A., Alexandra M Lopes, Amorim, António, Antonio Amorim, Carole A Sargent, Peter J Ellis, Miguel, Ricardo N., Affara, Nabeel A.   +11 more
core   +7 more sources

Sox10 escalates vascular inflammation by mediating vascular smooth muscle cell transdifferentiation and pyroptosis in neointimal hyperplasia

Cell Reports, 2023
Summary: Vascular smooth muscle cells (VSMCs) can transdifferentiate into macrophage-like cells in the context of sustained inflammatory injury, which drives vascular hyperplasia and atherosclerotic complications.
Xin Xu, Dan-Dan Zhang, Peng Kong, Ya-Kun Gao, Xiao-Fu Huang, Yu Song, Wen-Di Zhang, Rui-Juan Guo, Chang-Lin Li, Bo-Wen Chen, Yue Sun, Yong-Bo Zhao, Fang-Yue Jia, Xu Wang, Fan Zhang, Mei Han   +15 more
doaj   +1 more source

Sex determination in mythology and history [PDF]

, 2005
The history of ideas on how the sexes became divided spans at least three thousand years. The biblical account of the origin of Eve, and the opinions of the philosophers of classical Greece, have unexpected bearings on present-day ideas.
Mittwoch,Ursula, Mittwoch, U
core   +1 more source

Expression of EZH2 and SOX6 in patients with diabetic kidney disease and their correlation with renal function

Zhongguo linchuang yanjiu
Objective To investigate the serum levels of enhancer of zeste homolog 2 (EZH2) and sex-determining region Y box protein 6 (SOX6) in diabetic kidney disease (DKD) patients and their correlation with disease servity and renal function.
LI Zhicheng, HAO Yan, ZHENG Qiao, LI Peili
doaj   +1 more source

Does the linear Sry transcript function as a ceRNA for miR-138? The sense of antisense [v2; ref status: indexed, http://f1000r.es/4pd]

F1000Research, 2014
Recently, the sex determining region Y (Sry) and the cerebellar degeneration-related protein 1 (CDR1as) RNA transcripts have been described to function as a new class of post-transcriptional regulatory RNAs that behave as circular endogenous RNA sponges ...
Javier Tadeo Granados-Riveron, Guillermo Aquino-Jarquin   +1 more
doaj   +1 more source

Nerve regeneration by interferon intervention in aging brain

EMBO Molecular Medicine, 2023
Neural stem cells (NSCs) are shielded from viral infection by interferon (IFN) defense. As individuals age, activation of NSC decreases with a significant decline of stemness marker Sex‐determining region Y box 2 (Sox2) while IFN signaling enhances ...
Fanwen Wang, Duanqing Pei
doaj   +1 more source

Conflict over condition-dependent sex allocation can lead to mixed sex-determination systems [PDF]

, 2014
Theory suggests that genetic conflicts drive turnovers between sex-determining mechanisms, yet these studies only apply to cases where sex allocation is independent of environment or condition.
Kuijper, B, Pen, Ido, Pen, I, Kuijper, Bram   +3 more
core   +2 more sources

The genetics of sexual development in East African cichlid fishes [PDF]

, 2015
Sexual development leads to the formation of males and females. This process can be controlled genetically, environmentally or by a combination thereof. Genetic sex determination is based on single- or polygenic actions, either linked to sex chromosomes ...
Heule, Corina
core   +1 more source

Combined optical genome mapping and cnv-seq identify complex Y-chromosome rearrangements and ectopy in 46,XX testicular disorder of sex development

Molecular Cytogenetics
Objective To define the genomic architecture of Y‑chromosome ectopy in a child with 46,XX testicular disorders of sex development (DSD) and illustrate the complementary roles of low‑coverage CNV sequencing (CNV‑seq) and optical genome mapping (OGM ...
Hai Wang, Hao Wang, Zitong Xu, Penglong Chen, Xianjue Zheng, Haojie Pan, Hongping Zhang, Jiayong Zheng   +7 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source