Results 61 to 70 of about 31,435,271 (262)

The effects of the extract of oolong tea and its metabolites from Andraca theae in high fat diet induced obese Wistar rat

Food Science and Human Wellness, 2018
Obesity is a critical health issue worldwide. For a long time, the concept of drinking tea for health and pleasure is widely accepted. The strain of Andraca theae lives on the tea leaf and the bioactivity of its metabolites in the feces is unknown yet ...
Tung Yen-Chen, Hsieh Tsung-Hai, Yang Meei-Ju, Hung Wei-Lun, Ho Chi-Tang, Pan Min-Hsiung   +5 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Differentiation of Human Mesenchymal Stem Cells from Wharton’s Jelly Towards Neural Stem Cells Using a Feasible and Repeatable Protocol

Cells, 2020
The transplantation of neural stem cells (NSCs) capable of regenerating to the cells of the central nervous system (CNS) is a promising strategy in the treatment of CNS diseases and injury.
Ewa Kruminis-Kaszkiel, Adam Osowski, Ewa Bejer-Oleńska, Mariusz Dziekoński, Joanna Wojtkiewicz   +4 more
doaj   +1 more source

Porcine SOX9 Gene Expression Is Influenced by an 18 bp Indel in the 5'-Untranslated Region. [PDF]

PLoS ONE, 2015
Sex determining region Y-box 9 (SOX9) is an important regulator of sex and skeletal development and is expressed in a variety of embryonal and adult tissues.
Bertram Brenig, Yanyu Duan, Yuyun Xing, Nengshui Ding, Lusheng Huang, Ekkehard Schütz   +5 more
doaj   +1 more source

Systems analysis of human T helper17 cell differentiation uncovers distinct time-regulated transcriptional modules

iScience, 2021
Summary: T helper (Th) 17 cells protect from infections and are pathogenic in autoimmunity. While human Th17 cell differentiation has been defined, the global and stepwise transcriptional changes accompanying this process remain uncharacterized.
Alessia Capone, Chiara Naro, Manuela Bianco, Marco De Bardi, Floriane Noël, Paolo Macchi, Luca Battistini, Vassili Soumelis, Elisabetta Volpe, Claudio Sette   +9 more
doaj   +1 more source

Analysis of the role of the X/Y homologous gene family Xmr/Sly in murine spermiogenesis [PDF]

, 2009
Spermatogenesis is a complex, continuous developmental process that involves the formation of highly differentiated haploid sperm from diploid spermatogonial stem cells.
Reynard, L N, Reynard, L.N.
core  

Testis-determining factor and Y-linked sex reversal

, 1991
A gene named SRY, isolated last year from the sex-determining region of the human Y chromosome, satisfies many of the criteria expected of the testis-determining factor gene. Mutations in SRY have been found in XY females, strongly implicating SRY as the
Hawkins, J. Ross, Berta, Philippe, Koopman, Peter   +2 more
core   +1 more source

Something Fishy about Siamese Fighting Fish (Betta splendens) Sex: Polygenic Sex Determination or a Newly Emerged Sex-Determining Region?

, 2022
Fishes provide a unique and intriguing model system for studying the genomic origin and evolutionary mechanisms underlying sex determination and high sex-chromosome turnover.
Kongkaew, Lalida, Singchat, Worapong, Srikulnath, Kornsorn, Wongsathit Wongloet, Narongrit Muangmai, Kornsorn Srikulnath, Dokkaew, Sahabhop, Lalida Kongkaew, Panthum, Thitipong, Ekaphan Kraichak, Kraichak, Ekaphan, Prateep Duengkae, Wongloet, Wongsathit, Duengkae, Prateep, Kitipong Jaisamut, Syed Farhan Ahmad, Worapong Singchat, Muangmai, Narongrit, Sahabhop Dokkaew, Ahmad, Syed Farhan, Thitipong Panthum, Jaisamut, Kitipong   +21 more
core   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Clinical applications of serum tissue inhibitor of matrix metalloproteinase 3 and sex determining region Y box protein 2 for an early diagnosis of renal injury in type 2 diabetes mellitus

Linchuang shenzangbing zazhi
Objective To explore the roles of serum tissue inhibitor of matrix metalloproteinase 3（TIMP3） and sex determining region Y box protein 2（SOX2） in an early diagnosis of renal injury in type 2 diabetes mellitus（T2DM）. Methods From April 2022 to April 2023，
Hong-li Zhang, Hai-cheng Wang, Hua Li, Rui-chao Wei, Ling Zeng   +4 more
doaj   +1 more source