Results 71 to 80 of about 180,085 (282)
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Food Science and Human Wellness, 2018 Obesity is a critical health issue worldwide. For a long time, the concept of drinking tea for health and pleasure is widely accepted. The strain of Andraca theae lives on the tea leaf and the bioactivity of its metabolites in the feces is unknown yet ...
Tung Yen-Chen +5 more
doaj +1 more source
Impact of SOX2 function and regulation on therapy resistance in bladder cancer
Frontiers in Oncology, 2022 Bladder cancer (BC) is a malignant disease with high rates of recurrence and mortality. It is mainly classified as non-muscle-invasive BC and muscle-invasive BC (MIBC).
Guodong Chen +11 more
doaj +1 more source
初期胚細胞においてSex-determining region Y-box 2とGA-binding proteinsがLiver receptor homolog-1の転写調節を行う
初期胚細胞においてSex-determining region Y-box 2とGA-binding proteinsがLiver receptor homolog-1の転写調節を行う真史 菅野
openaire +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Cells, 2020 The transplantation of neural stem cells (NSCs) capable of regenerating to the cells of the central nervous system (CNS) is a promising strategy in the treatment of CNS diseases and injury.
Ewa Kruminis-Kaszkiel +4 more
doaj +1 more source
Porcine SOX9 Gene Expression Is Influenced by an 18 bp Indel in the 5'-Untranslated Region. [PDF]
PLoS ONE, 2015 Sex determining region Y-box 9 (SOX9) is an important regulator of sex and skeletal development and is expressed in a variety of embryonal and adult tissues.
Bertram Brenig +5 more
doaj +1 more source
Vestibular Nuclei: A New Neural Stem Cell Niche?
Cells, 2022 We previously reported adult reactive neurogliogenesis in the deafferented vestibular nuclei following unilateral vestibular neurectomy (UVN) in the feline and the rodent model.
Guillaume Rastoldo +5 more
doaj +1 more source
Increased expression of the pluripotency markers sex-determining region Y-box 2 and Nanog homeobox in ovarian endometriosis [PDF]
, 2014 BACKGROUND: The precise etiology of endometriosis is not fully understood; the involvement of stem cells theory is a new hypothesis. Related studies mainly focus on stemness-related genes, and pluripotency markers may play a role in the etiology of ...
Jing Fu +6 more
core +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source