Results 31 to 40 of about 31,435,271 (262)

Locating the sex determining region of linkage group 12 of guppy (Poecilia reticulata) [PDF]

, 2020
Despite over 100 years of study, the location of the fully sex-linked region of the guppy (Poecilia reticulata) carrying the male-determining locus, and the regions where the XY pair recombine, remain unclear.
Graham, Chay, Bergero, Roberta, Yong, Lengxob, Gardner, Jim, Charlesworth, Deborah   +4 more
core   +1 more source

Lysine 68 Methylation‐Dependent SOX9 Stability Control Modulates Chondrogenic Differentiation in Dental Pulp Stem Cells

Advanced Science, 2023
Dental pulp stem cells (DPSCs), characterized by easy availability, multi‐lineage differentiation ability, and high proliferation ability, are ideal seed cells for cartilage tissue engineering.
Qiannan Sun, Zimeng Zhuang, Rushui Bai, Jie Deng, Tianyi Xin, Yunfan Zhang, Qian Li, Bing Han   +7 more
doaj   +1 more source

Sox10 escalates vascular inflammation by mediating vascular smooth muscle cell transdifferentiation and pyroptosis in neointimal hyperplasia

Cell Reports, 2023
Summary: Vascular smooth muscle cells (VSMCs) can transdifferentiate into macrophage-like cells in the context of sustained inflammatory injury, which drives vascular hyperplasia and atherosclerotic complications.
Xin Xu, Dan-Dan Zhang, Peng Kong, Ya-Kun Gao, Xiao-Fu Huang, Yu Song, Wen-Di Zhang, Rui-Juan Guo, Chang-Lin Li, Bo-Wen Chen, Yue Sun, Yong-Bo Zhao, Fang-Yue Jia, Xu Wang, Fan Zhang, Mei Han   +15 more
doaj   +1 more source

A model system for study of sex chromosome effects on sexually dimorphic neural and behavioral traits [PDF]

, 2002
We tested the hypothesis that genes encoded on the sex chromosomes play a direct role in sexual differentiation of brain and behavior. We used mice in which the testis-determining gene (Sry) was moved from the Y chromosome to an autosome (by deletion of ...
Robin Lovell-Badge, De Vries, Geert, Auger, CJ, Lovell-Badge, R, Catherine J. Auger, Elka M. Scordalakes, Swain, A, Simerly, Richard B., Lovell-Badge, Robin, Richard B. Simerly, Amanda Swain, Arnold, Arthur P., Simerly, RB, Burgoyne, PS, Scordalakes, Elka M., Emilie F. Rissman, Geert J. De Vries, Liang-Yo Yang, Burgoyne, Paul S., Yang, Liang-Yo, Yang, L-Y, Rissman, EF, Rissman, Emilie F., Paul S. Burgoyne, De Vries, G, Arnold, AP, Arthur P. Arnold, Scordalakes, EM, Swain, Amanda, Auger, Catherine J.   +29 more
core   +1 more source

Expression of EZH2 and SOX6 in patients with diabetic kidney disease and their correlation with renal function

Zhongguo linchuang yanjiu
Objective To investigate the serum levels of enhancer of zeste homolog 2 (EZH2) and sex-determining region Y box protein 6 (SOX6) in diabetic kidney disease (DKD) patients and their correlation with disease servity and renal function.
LI Zhicheng, HAO Yan, ZHENG Qiao, LI Peili
doaj   +1 more source

Does the linear Sry transcript function as a ceRNA for miR-138? The sense of antisense [v2; ref status: indexed, http://f1000r.es/4pd]

F1000Research, 2014
Recently, the sex determining region Y (Sry) and the cerebellar degeneration-related protein 1 (CDR1as) RNA transcripts have been described to function as a new class of post-transcriptional regulatory RNAs that behave as circular endogenous RNA sponges ...
Javier Tadeo Granados-Riveron, Guillermo Aquino-Jarquin   +1 more
doaj   +1 more source

Nerve regeneration by interferon intervention in aging brain

EMBO Molecular Medicine, 2023
Neural stem cells (NSCs) are shielded from viral infection by interferon (IFN) defense. As individuals age, activation of NSC decreases with a significant decline of stemness marker Sex‐determining region Y box 2 (Sox2) while IFN signaling enhances ...
Fanwen Wang, Duanqing Pei
doaj   +1 more source

Combined optical genome mapping and cnv-seq identify complex Y-chromosome rearrangements and ectopy in 46,XX testicular disorder of sex development

Molecular Cytogenetics
Objective To define the genomic architecture of Y‑chromosome ectopy in a child with 46,XX testicular disorders of sex development (DSD) and illustrate the complementary roles of low‑coverage CNV sequencing (CNV‑seq) and optical genome mapping (OGM ...
Hai Wang, Hao Wang, Zitong Xu, Penglong Chen, Xianjue Zheng, Haojie Pan, Hongping Zhang, Jiayong Zheng   +7 more
doaj   +1 more source

The Adipokine Visfatin Modulates Cancer Stem Cell Properties in Triple-Negative Breast Cancer

Biomedicines, 2023
Obesity is a cancer progression risk factor; excessive adipocytes increase adipokine secretion. Visfatin, a novel adipokine highly expressed in cancer patients, is related to breast cancer risk.
Yi-Fen Chiang, Ko-Chieh Huang, Hsin-Yuan Chen, Tsui-Chin Huang, Mohamed Ali, Hsin-Yi Chang, Tzong-Ming Shieh, Yin-Hwa Shih, Kai-Lee Wang, Yun-Ju Huang, Cheng-Pei Chung, Shih-Min Hsia   +11 more
doaj   +1 more source

Sex determination in mythology and history [PDF]

, 2005
The history of ideas on how the sexes became divided spans at least three thousand years. The biblical account of the origin of Eve, and the opinions of the philosophers of classical Greece, have unexpected bearings on present-day ideas.
Mittwoch,Ursula, Mittwoch, U
core   +1 more source