Results 71 to 80 of about 4,675,098 (246)

The fourspine stickleback (Apeltes quadracus) has an XY sex chromosome system with polymorphic inversions on both X and Y chromosomes.

PLoS Genetics
Teleost fish are well-known for possessing a diversity of sex chromosomes and for undergoing frequent turnovers of these sex chromosomes. However, previous studies have mainly focused on variation between species, while comparatively little attention has
Zuyao Liu, Amy L Herbert, Yingguang Frank Chan, Marek Kučka, David M Kingsley, Catherine L Peichel   +5 more
doaj   +1 more source

The asparagus genome sheds light on the origin and evolution of a young Y chromosome

Nature Communications, 2017
Several models have been proposed to explain the emergence of sex chromosomes. Here, through comparative genomics and mutant analysis, Harkess et al.
Alex Harkess, Jinsong Zhou, Chunyan Xu, John E. Bowers, Ron Van der Hulst, Saravanaraj Ayyampalayam, Francesco Mercati, Paolo Riccardi, Michael R. McKain, Atul Kakrana, Haibao Tang, Jeremy Ray, John Groenendijk, Siwaret Arikit, Sandra M. Mathioni, Mayumi Nakano, Hongyan Shan, Alexa Telgmann-Rauber, Akira Kanno, Zhen Yue, Haixin Chen, Wenqi Li, Yanling Chen, Xiangyang Xu, Yueping Zhang, Shaochun Luo, Helong Chen, Jianming Gao, Zichao Mao, J. Chris Pires, Meizhong Luo, Dave Kudrna, Rod A. Wing, Blake C. Meyers, Kexian Yi, Hongzhi Kong, Pierre Lavrijsen, Francesco Sunseri, Agostino Falavigna, Yin Ye, James H. Leebens-Mack, Guangyu Chen   +41 more
doaj   +1 more source

Meiosis reveals the early steps in the evolution of a neo-XY sex chromosome pair in the African pygmy mouse Mus minutoides.

PLoS Genetics, 2020
Sex chromosomes of eutherian mammals are highly different in size and gene content, and share only a small region of homology (pseudoautosomal region, PAR).
Ana Gil-Fernández, Paul A Saunders, Marta Martín-Ruiz, Marta Ribagorda, Pablo López-Jiménez, Daniel L Jeffries, María Teresa Parra, Alberto Viera, Julio S Rufas, Nicolas Perrin, Frederic Veyrunes, Jesús Page   +11 more
doaj   +1 more source

Chromosomal Analysis in Crotophaga ani (Aves, Cuculiformes) Reveals Extensive Genomic Reorganization and an Unusual Z-Autosome Robertsonian Translocation

Cells, 2020
Although cytogenetics studies in cuckoos (Aves, Cuculiformes) have demonstrated an interesting karyotype variation, such as variations in the chromosome morphology and diploid number, their chromosome organization and evolution, and relation with other ...
Rafael Kretschmer, Ricardo José Gunski, Analía del Valle Garnero, Thales Renato Ochotorena de Freitas, Gustavo Akira Toma, Marcelo de Bello Cioffi, Edivaldo Herculano Corrêa de Oliveira, Rebecca E. O’Connor, Darren K. Griffin   +8 more
doaj   +1 more source

Sex determination in mythology and history [PDF]

, 2005
The history of ideas on how the sexes became divided spans at least three thousand years. The biblical account of the origin of Eve, and the opinions of the philosophers of classical Greece, have unexpected bearings on present-day ideas.
Mittwoch,Ursula, Mittwoch, U
core   +1 more source

Integrating Genetics With Epidemiological Measurements Identifies Burden QTLs of Inflammatory Bowel Disease across 20 Countries

Advanced Science, EarlyView.
The burden quantitative trait locus (bQTL) analysis integrates epidemiological data from GBD study with genotype of 2 621 978 SNPs from 2414 individuals in 1000 Genomes Project across 20 countries. rs7633471 shows the strongest effect that each increase in centi‐allele frequency of the allele C associated with 10.00 decrease of age‐standardized ...
Chen Sun, Siyu Wei, Junxian Tao, Haiyan Chen, Chi Yan, Jiacheng Wang, Jing Xu, Lian Duan, Yuanbo Zhan, Yuping Zou, Ruilin Li, Linna Yuan, Wei She, Songlin Lu, Ning Wang, Qinduo Ren, Yan Guo, Yuan Xu, Chang Wang, Hongsheng Tian, Chen Zhang, Yu Dong, Guoping Tang, Zhenwei Shang, Yongshuai Jiang, Wenhua Lv, Mingming Zhang, Hongchao Lyu   +27 more
wiley   +1 more source

Paradigm shift in sex chromosome evolution

Explaining the variation in sex-determining mechanisms across the tree of life and understanding the evolution of sex chromosomes represent important goals in evolutionary biology.
Workshop: Paradigm Shift in Sex Chromosome Evolution (2019 : Berlin), Leibniz-Institut für Gewässerökologie und Binnenfischerei, Deutsche Forschungsgemeinschaft, Stöck, Matthias, Kratochvíl, Lukáš   +4 more
core   +1 more source

Parallel divergence and degradation of the avian W sex chromosome

, 2007
Sex chromosomes are ubiquitous in birds but our understanding of how they originated and evolved has remained incomplete. Recent work by Tsuda et al. on tinamou and ratite birds suggests that, although all bird sex chromosomes evolved from the same pair ...
Ellegren, Hans,, Mank, Judith E.,
core   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

Mechanisms and evolutionary patterns of mammalian and avian dosage compensation.

PLoS Biology, 2012
As a result of sex chromosome differentiation from ancestral autosomes, male mammalian cells only contain one X chromosome. It has long been hypothesized that X-linked gene expression levels have become doubled in males to restore the original ...
Philippe Julien, David Brawand, Magali Soumillon, Anamaria Necsulea, Angélica Liechti, Frédéric Schütz, Tasman Daish, Frank Grützner, Henrik Kaessmann   +8 more
doaj   +1 more source