Results 81 to 90 of about 4,675,098 (246)

A Genetic Map of Ostrich Z Chromosome and the Role of Inversions in Avian Sex Chromosome Evolution

, 2018
Recombination arrest is a necessary step for the evolution of distinct sex chromosomes. Structural changes, such as inversions, may represent the mechanistic basis for recombination suppression and comparisons of the structural organization of ...
Yazdi, Homa Papoli, Ellegren, Hans, Ellegren, Hans,, Yazdi, Homa Papoli,   +3 more
core   +1 more source

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

Advanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li, Yirui Fan, Dandan Geng, Lei Wang   +12 more
wiley   +1 more source

Sex chromosome evolution in moths and butterflies [PDF]

Chromosome Research, 2011
Lepidoptera, i.e. moths and butterflies, have a female heterogametic sex chromosome system, with most females having a WZ constitution while males are ZZ. Besides this predominant WZ/ZZ system, Z/ZZ, WZ(1)Z(2)/Z(1)Z(1)Z(2)Z(2) and W(1)W(2)Z/ZZ systems also occur.
Sahara, Ken, Yoshido, Atsuo, Traut, Walther   +2 more
openaire   +3 more sources

Bidirectional transcription of a novel chimeric gene mapping to mouse chromosome Yq. [PDF]

, 2007
Background The male-specific region of the mouse Y chromosome long arm (MSYq) contains three known highly multi-copy X-Y homologous gene families, Ssty1/2, Sly and Asty.
Nabeel A Affara, Ellis, Peter J.I., Clemente, Emily J., Peter JI Ellis, Emily J Clemente, Ferguson, Lydia, Affara, Nabeel A., Lydia Ferguson   +7 more
core   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

Advanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan, Fuming Cao, Junqiang Mao, Pengbin Yin, Licheng Zhang, Jianjun Wang, Peifu Tang   +6 more
wiley   +1 more source

Rapid turnover of sex chromosomes is associated with speciation in Neotropical armored catfish Harttia (Siluriformes, Loricariidae)

Biology Direct
Background The Neotropical armored catfish genus Harttia is an exceptional model for studying sex chromosome evolution, as it harbors the highest diversity of multiple sex chromosome systems known among fishes.
Francisco de Menezes Cavalcante Sassi, Fernando Henrique Santos de Souza, Manolo Fernandez Perez, Foyez Shams, Tariq Ezaz, Geize Aparecida Deon, Thomas Liehr, Luohao Xu, Marcelo de Bello Cioffi   +8 more
doaj   +1 more source

From homomorphy to heteromorphy: stratified trajectories of sex chromosome expansion in Silene latifolia

Genomics Communications
A recent analysis of the Silene latifolia Y chromosome has demonstrated that suppressed recombination drives its expansion into evolutionary strata and accelerates functional degeneration through transposable element accumulation, DNA hypermethylation ...
Dan Peng, Luke R. Tembrock, Liang Tang
doaj   +1 more source

High degree of sex chromosome differentiation in stickleback fishes

BMC Genomics, 2011
Background Studies of closely related species with different sex chromosome systems can provide insights into the processes of sex chromosome differentiation and evolution.
Shimada Yukinori, Natri Heini M, Shikano Takahito, Merilä Juha   +3 more
doaj   +1 more source

Genetic conflict and sex chromosome evolution

Trends in Ecology & Evolution, 2010
Chromosomal sex determination systems create the opportunity for the evolution of selfish genetic elements that increase the transmission of one sex chromosome at the expense of its homolog. Because such selfish elements on sex chromosomes can reduce fertility and distort the sex ratio of progeny, unlinked suppressors are expected to evolve, bringing ...
Meiklejohn, Colin D., Tao, Yun
openaire   +3 more sources

Steps in the evolution of heteromorphic sex chromosomes [PDF]

Heredity, 2005
We review some recently published results on sex chromosomes in a diversity of species. We focus on several fish and some plants whose sex chromosomes appear to be 'young', as only parts of the chromosome are nonrecombining, while the rest is pseudoautosomal. However, the age of these systems is not yet very clear. Even without knowing what proportions
Charlesworth, D., Charlesworth, B., Marais, Gabriel   +2 more
openaire   +3 more sources