Results 51 to 60 of about 20,923 (214)
: OBJECTIVE: To determine prospectively the relationship between insulin resistanceand sex hormone binding globulin(SHBG) in connection with risk ofdeveloping diabetes in male offspring oftype 2 diabetics.
Muhammad Ijaz Anwar +2 more
doaj
ABSTRACT Background Traditionally, Klinefelter syndrome (KS) was considered a clinical condition associated with hyperestrogenism. Aim To compare circulating sex steroids, particularly estrogens, in a cohort of KS and non‐KS hypogonadal men. Materials and Methods A cohort of hypogonadal men, treated and untreated, was prospectively enrolled in a real ...
Daniele Renda Livraghi +8 more
wiley +1 more source
ABSTRACT Introduction Maternal intake of artificial sweeteners in beverages (ASB) during pregnancy may have a programming effect on offspring health, including biomarkers of male fecundity. Objective We investigated whether maternal intake of ASB during pregnancy was associated with biomarkers of male fecundity in adult sons.
Frida Vinther Hauberg +7 more
wiley +1 more source
ABSTRACT Introduction Gender‐affirming hormone therapy (GAHT) may be associated with increased cardiometabolic disease (CMD) risk. Prospective CMD risk screening is recommended, but long‐term data are needed regarding changes in CMD markers. Objectives To evaluate prospective changes in CMD risk markers during GAHT.
Louise Lehmann Christensen +7 more
wiley +1 more source
Sex hormone-binding globulin, androgens and mortality: the KORA-F4 cohort study
Objective: Sex hormone-binding globulin (SHBG) and androgens have been associated with mortality in women and men, but controversy still exists. Our objective was to investigate associations of SHBG and androgens with all-cause a nd cause-specific ...
Florian Schederecker +8 more
doaj +1 more source
Father–Son Comparison of Reproductive Traits
ABSTRACT Background Little is known about the relative contribution of genetic and environmental factors on male reproductive function. Objectives We studied in a cross‐sectional setting, whether testicular function and genital size correlate in father–son pairs.
Heidi Elamo +9 more
wiley +1 more source
INTRODUCTION: gonadal steroid hormones play a crucial role during skeletal growth and maturation in both men and women. The aim of this study is to evaluate the relationship of sex hormone levels, bone mineral density and biochemical markers of bone ...
Aissam El Maataoui +4 more
doaj +1 more source
Among 170,250 UK Biobank women (2006–2024), ever HRT use was associated with higher incident ASCVD risk (adjusted HR 1.13, 95% CI 1.08–1.18), largely driven by ischemic stroke. Associations were stronger in women ≤45 years and during perimenopause. Mediation via sex hormones, inflammatory markers, or lipids was minimal (<2%).
Mengchun Wang +6 more
wiley +1 more source
Background: Metformin, which is a biguanide is administered in patients with Type 2 Diabetes Mellitus, mainly works on by decreasing the synthesis & subsequent production of glucose in the liver via attenuating the hepatic gluconeogenesis.
SUHENA SARKAR +5 more
doaj +1 more source
Pubertal Dynamics of Sertoli and Leydig Cell Dysfunction in Klinefelter Syndrome
ABSTRACT Context Klinefelter syndrome (KS), defined by a 47, XXY karyotype, is commonly associated with progressive testicular failure. The precise timing of Sertoli and Leydig cell dysfunction during puberty remains unclear. Objective To determine the onset and progression of testicular insufficiency during puberty in KS, and to assess whether ...
Tredez Axelle +9 more
wiley +1 more source

