Results 121 to 130 of about 21,005 (271)

Expression of GNAQ, BAP1, SF3B1, and EIF1AX Proteins in the Aqueous Humor of Eyes Affected by Uveal Melanoma.

Investigative Ophthalmology and Visual Science
Purpose The purpose of this study was to quantify specific aqueous humor (AH) proteins in eyes affected by posterior uveal melanoma (UM). Methods Thirty-six eyes affected by primary UM were included.
G. Midena, R. Parrozzani, L. Frizziero, Graziana Esposito, A. Micera, E. Midena   +5 more
semanticscholar   +1 more source

WHO classification of skin tumours: key updates in the fifth edition

Histopathology, Volume 88, Issue 3, Page 555-568, February 2026.
This review article summarizes the key updates in the 5th edition of the WHO Classification of Skin Tumours. It provides an overview of the major changes and new entities specific to the skin section, covering areas such as epidermal, melanocytic, mesenchymal and other tumours. The 5th edition of the World Health Organization Classification of Tumours (
Gabrielle Goldman‐Lévy, Raymond Barnhill, Boris C. Bastian, Werner Kempf, David Elder, Pedram Gerami, Wayne Grayson, Dmitry Kazakov, Daniela Massi, Jane Messina, Arnaud de la Fouchardière, Alexander J. Lazar, Thomas Brenn, Brian Rous, Andrew Field, Anthony Gill, Jennelle C. Hodge, Joseph D Khoury, Katia Leite, Shahin Sayed, Puay Hoon Tan, Rosalie Elenitsas, Eduardo Calonje, Lyn M. Duncan, Liang Zhiyong, Holger Moch, Rajendra Singh, Harshima Wijesinghe, Ian Cree, Dilani Lokuhetty   +29 more
wiley   +1 more source

Analysis of SF3B1 mutations in monoclonal B‐cell lymphocytosis [PDF]

Hematological Oncology, 2012
[No abstract available]
Mariangela Greco, Daniela Capello, Alessio Bruscaggin, Valeria Spina, Silvia Rasi, Sara Monti, Carmela Ciardullo, Stefania Cresta, Marco Fangazio, Gianluca Gaidano, FOA, Roberto, Davide Rossi   +11 more
openaire   +4 more sources

Antitumor activity of splicing inhibitor pladienolide B in erythroleukemia: a study in cell lines [PDF]

, 2015
Trabalho final de mestrado integrado em Medicina (Hematologia/Biologia Molecular), apresentado à Faculdade de Medicina da Universidade de Coimbra.The splicing of pre-mRNA into functional mRNA, carried out by the spliceosome, represents a crucial step ...
Petronilho, Sara Lopes
core  

Metastatic disease in polyploid uveal melanoma patients is associated with BAP1 mutations [PDF]

, 2016
PURPOSE. Most of the uvea melanoma (UM) display a near-diploid (normal, ~2N) karyotype with only a few chromosomal changes. In contrast to these simple aberrations 18% of the UM samples show a polyploid character (>2N) and this was associated with an ...
Beverloo, H.B. (Berna), Brüggenwirth, H.T. (Hennie), Dubbink, H.J. (Erik Jan), Kiliç, E. (Emine), Klein, A. (Annelies) de, Marion, R. (Ronald) van, Mensink, H.W. (Hanneke), Naus, N.C. (Nicole), Paridaens, A.D.A. (Dion), Smit, K.N. (Kyra), Vaarwater, J. (Jolanda), Verdijk, R.M. (Robert), Yavuzyigitoglu, S. (Serdar)   +12 more
core   +1 more source

Supplementary Table from Splicing Patterns in <i>SF3B1</i>-Mutated Uveal Melanoma Generate Shared Immunogenic Tumor-Specific Neoepitopes

, 2023
Jérémy Bigot, Ana I. Lalanne, Francesca Lucibello, Paul Gueguen, Alexandre Houy, Stéphane Dayot, Olivier Ganier, Jules Gilet, Jimena Tosello, Fariba Némati, Gaëlle Pierron, Joshua J. Waterfall, Raymond L. Barnhill, Sophie Gardrat, Sophie Piperno‐Neumann, Tatiana Popova, Vanessa Masson, Damarys Loew, Pascale Mariani, Nathalie Cassoux, Sebastián Amigorena, Manuel Rodrigues, Samar Alsafadi, Marc‐Henri Stern, Olivier Lantz   +24 more
openalex   +2 more sources

Predicting survival in patients with myelodysplastic/myeloproliferative neoplasms with SF3B1 mutation and thrombocytosis

Leukemia
We investigated data from 180 consecutive patients with myelodysplastic/myeloproliferative neoplasms with SF3B1 mutation and thrombocytosis (MDS/MPN-SF3B1-T) who were diagnosed according to the 2022 World Health Organization (WHO) classification of ...
Fuhui Li, T. Qin, Bing Li, Shiqiang Qu, L. Pan, Peihong Zhang, Qi Sun, W. Cai, Qingyan Gao, M. Jiao, Junjie Li, X. Ai, Jiao Ma, R. Gale, Zefeng Xu, Zhijian Xiao   +15 more
semanticscholar   +1 more source

Inferring clonal evolution of tumors from single nucleotide somatic mutations [PDF]

, 2013
High-throughput sequencing allows the detection and quantification of frequencies of somatic single nucleotide variants (SNV) in heterogeneous tumor cell populations.
Deshwar, Amit G., Jiao, Wei, Morris, Quaid, Stein, Lincoln, Vembu, Shankar   +4 more
core   +2 more sources

Altered RNA export by SF3B1 mutants confers sensitivity to nuclear export inhibition

Leukemia
SF3B1 mutations frequently occur in cancer yet lack targeted therapies. Clinical trials of XPO1 inhibitors, selinexor and eltanexor, in high-risk myelodysplastic neoplasms (MDS) revealed responders were enriched with SF3B1 mutations.
S. Chaudhry, F. Beckedorff, S. Jasdanwala, T. Totiger, Maurizio Affer, Abimbo Lawal, S. Montoya, Francesco Tamiro, Olivia Tonini, Alexandra Chirino, Andrew Adams, Anya K. Sondhi, Stephen Noudali, A. Cornista, Miah Nicholls, Jumana Afaghani, Paola Robayo, Daniel Bilbao, Stephen D. Nimer, Josean Rodriguez, Shruti Bhatt, Eric Wang, Justin Taylor   +22 more
semanticscholar   +1 more source

Biological heterogeneity in adult IRF4‐rearranged large B‐cell lymphoma: Stratification by age and anatomical site

HemaSphere, Volume 10, Issue 1, January 2026.
Abstract Large B‐cell lymphoma (LBCL) with IRF4 rearrangement (LBCL‐IRF4‐R) is a rare subtype predominantly diagnosed in children and young adults. Whether adult LBCL cases with IRF4 rearrangement (IRF4‐R) should be classified as LBCL‐IRF4‐R remains unclear. Clinicopathological and molecular features of 61 adult LBCL cases with IRF4‐R were analyzed and
Yuxiu Zhang, Anqi Li, Yimin Li, Xuan Wang, Lei Dong, Lei Zhang, Pengpeng Xu, Yue Wang, Xia Shen, Haimin Xu, Binshen Ouyang, Chaofu Wang, Hongmei Yi   +12 more
wiley   +1 more source