Results 131 to 140 of about 12,272 (217)

SF3B1: from core splicing factor to oncogenic driver

RNA
Highly recurrent somatic mutations in the gene encoding the core splicing factor SF3B1 are drivers of multiple cancer types. SF3B1 is a scaffold protein that orchestrates multivalent protein–protein interactions within the spliceosome that are essential for recognizing the branchsite (BS) and selecting the 3′ splice site during the earliest stage of ...
Bak-Gordon, Pedro, Manley, James L.
openaire   +2 more sources

SF3B1 Gene Mutation [PDF]

, 2020
openaire   +1 more source

SF3B1 wt Allele [PDF]

, 2020
openaire   +1 more source

P1052: IMPACT OF SF3B1 MUTATION IN MYELOFIBROSIS

HemaSphere, 2022
J. Senapati, S. Verstovsek, L. Masarova, N. Pemmaraju, G. Montalban Bravo, S. Pierce, L. Zhou, G. Garcia-Manero, H. Kantarjian, P. Bose   +9 more
openaire   +2 more sources

NEOPLASIAS MIELOIDES COM MUTAÇÃO SF3B1

Hematology, Transfusion and Cell Therapy, 2022
LR Fernandes, VRH Nunes, PEM Peonorio, LGF Cortes, SEA Rosa, CN Silveira, LB Lima, E Velloso, P Campregher   +8 more
openaire   +1 more source

Genomic and epigenomic landscape of triple negative myelodysplastic/myeloproliferative neoplasia with SF3B1 mutation and thrombocytosis

Les néoplasies myélodysplasiques, myéloprolifératives avec mutation de SF3B1 et thrombocytose sont des pathologies clonales de la cellule souche hématopoïétique regroupant des caractéristiques communes aux néoplasies myélodysplasiques (MDS) et aux ...
Divoux, Marion
core  

From silos to synergy: the interdisciplinary discovery potential in redefining polyendocrine metabolic ovarian syndrome. [PDF]

J Clin Invest
Morhaus MM, McLester-Davis LWY, Simcox JA.   +2 more
europepmc   +1 more source

Anatomical location defines distinct molecular subtypes of mucosal melanoma. [PDF]

ESMO Open
Zhou ER, Rusheen J, Baumann R, Ariyan S, Kluger HM, Gabizon-Peretz S.   +5 more
europepmc   +1 more source

P027 | Spalt-like transcription factor 4 deregulation in low risk myelodysplastic syndrome SF3B1-mutated patients

Haematologica
Introduction: Myelodysplastic syndromes (MDS) represent a heterogeneous group of clonal hematopoietic stem cell neoplasms characterized by ineffective hematopoiesis, peripheral cytopenias, and variable risk of progression to AML.
Eleonora Lumia
doaj  

SF3B1 phosphorylation is an evolutionarily conserved step in spliceosome activation carried out by the divergent, OTS964-insensitive kinase CRK9 in trypanosomes. [PDF]

Nucleic Acids Res
Machida K, Rattan P, Cassidento S, Peterman N, Hao B, Günzl A.   +5 more
europepmc   +1 more source