Results 151 to 160 of about 12,272 (217)

Synergistic effect of Pladienolide B and cisplatin: enhancing autophagy in hepatoma cells through the AMPK/mTOR/ULK1 pathway. [PDF]

Cell Death Discov
Xiao W, Yang L, Li Z, Wang W, Liu Z, Liu B, Qin J, Li Y.   +7 more
europepmc   +1 more source

The Roles of Genetic and Epigenetic Abnormalities in Essential Thrombocythemia. [PDF]

Genes (Basel)
Strzała D, Homenda W, Połom A, Kellas A, Bilska S, Paszek S, Potocka-Wojtowicz N, Zawlik I.   +7 more
europepmc   +1 more source

Different <i>SF3B1</i> Mutation Hotspots Show Hematopoietic Lineage-Specific VAF Patterns and Correlate with Distinct Genetic and Prognostic Profiles in Patients with Myeloid Neoplasms. [PDF]

Cancers (Basel)
Calvete O, Mestre J, Zamora L, Chaparro-González L, Ruiz Pérez-Hita L, Torres-Esquius S, Montoro MJ, Xicoy B, Solé F.   +8 more
europepmc   +1 more source

SF3B1 mutations in patients with myelodysplastic syndromes: the mutation is stable during disease evolution

[[abstract]]The SF3B1 mutation can be detected in patients with myelodysplastic syndrome (MDS), but the report regarding the association of this mutation with other genetic alterations and its stability during disease progression is limited.
Wu, Shang-Ju, Tang, Jih-Luh, Ko, Bor-Sheng, Lin, Chien-Chin, Hou, Hsin-An, Chou, Wen-Chien, Huang, Chi-Fei, Yao, Ming, Liu, Chieh-Yu, Tsay, Woei, Tseng, Mei-Hsuan, Liu, Ming-Chih, Hsu, Szu-Chun, Chen, Yao-Chang, Chen, Chien-Yuan, Lee, Fen-Yu, Kuo, Yuan-Yeh, Huang, Shang-Yi, Liu, Chia-Wen, Tien, Hwei-Fang   +19 more
core  

An antisense antidote to oncogenic poison exons. [PDF]

Genes Dev
Arvola RM, Singh G.
europepmc   +1 more source

The Role of Splicing Machinery as a Promising Potential Therapeutic Target for Pituitary Neuroendocrine Tumors (PitNETs). [PDF]

Cancers (Basel)
Mangili F, Treppiedi D, Peverelli E, Mantovani G.   +3 more
europepmc   +1 more source

Systems genetics approaches model the heritable architecture of polyendocrine metabolic ovarian syndrome. [PDF]

J Clin Invest
Nguyen CM, Velez LM, Cheon Y, Jackson CL, Johnson CD, Tamburini I, Zhou M, Alvstad E, Yoon I, Dustagheer F, Li M, Gujjarlapudi T, Ofilan K, Mishra N, Williams EG, Kwan D, Viesi CH, Ujagar N, Ashbrook DG, Senior A, Nelson ME, Pannunzio NR, Masri S, Kvon EZ, MacGregor G, Jang C, Sebastiano V, Byun M, Xiao C, Kauffman AS, Williams RW, James DE, Marazzi I, Nicholas D, Seldin M.   +34 more
europepmc   +1 more source

Tumor cell intrinsic dsRNA innate immune response triggered by PARP inhibitor is compromised in BRCA1-deficient breast cancer by repressing IRF3. [PDF]

Protein Cell
Zhang C, Zhou JB, Lei JH, Ang IL, Miao K, Xu X, Poon TCW, Cheung E, Deng CX.   +8 more
europepmc   +1 more source

Concurrent <i>SF3B1</i> Mutation and <i>BCR::ABL1</i> Demonstrating a Myelodysplastic Syndrome Phenotype: A Case Report. [PDF]

EJHaem
Brailovski E, Vahedi A, Lisi V, Dmitrienko S, Mercier FE, Lavallée VP, Assouline S.   +6 more
europepmc   +1 more source

Mutational dynamics in patients with del(5q) MDS treated with lenalidomide prior to transfusion dependency-Molecular results from the Sintrarev clinical trial. [PDF]

Hemasphere
Toribio Castelló S, López-Cadenas F, Preudhomme C, González T, Villaverde Ramiro A, Fenwarth L, Xicoy B, Renneville A, Sánchez-Garcia J, Coll R, Slama B, Hernández-Rivas JÁ, Thepot S, Bernal T, Guerci-Bresler A, Azibeiro R, Del Rey M, Götze KS, Fenaux P, Hernández-Rivas JM, Díez-Campelo M.   +20 more
europepmc   +1 more source