Results 191 to 200 of about 12,272 (217)

Comparison of the clinicopathological features in myeloproliferative or myelodysplastic neoplasms with SF3B1/JAK2, SF3B1/CALR, or SF3B1/MPL co-mutations.

Leukemia & lymphoma
Mutations in JAK2, CALR, and MPL account for over 90% of Philadelphia-negative (Ph-) myeloproliferative neoplasm (MPN), while SF3B1 mutations are diagnostic for myelodysplasia in myelodysplastic syndrome (MDS) or myelodysplastic/myeloproliferative neoplasm (MDS/MPN).
Richard, Shao, Le, Wang, Hailing, Zhang, Michael, Martin, Lynn, Moscinski, Amy, Li, Julie, Li, Jinming, Song   +7 more
openaire   +1 more source

101 SF3B1 Mutation and Overlapping Features of MDS/MPN-SF3B1-T and CLL: A Diagnostic Challenge

American Journal of Clinical Pathology
Abstract Introduction/Objective SF3B1 mutations are associated with several hematologic malignancies, including chronic lymphocytic leukemia (CLL) and myelodysplastic/myeloproliferative neoplasms with SF3B1 mutation and thrombocytosis (MDS/MPN-SF3B1-T). CLL cases with SF3B1 mutations often show
Zehra Kocas, Ali Tug, Jonathan Freeman
openaire   +1 more source

A Murine Model Harboring Cooperating DNMT3A and SF3B1 Mutations Phenocopies SF3B1 Driven Myelodysplastic Syndrome

Blood, 2022
Lashanale Wallace, Ana Leal-Cervantes, Amina Metidji, Jacquelyn Myers, Chandra Rolle, Heather Tillman, Esther A. Obeng   +6 more
openaire   +1 more source

Mutant SF3B1 splices a more leukemogenic EVI1

Blood, 2022
openaire   +2 more sources

Cancer-associated mutations in SF3B1 disrupt the interaction between SF3B1 and DDX42

Journal of Biochemistry, 2022
Xin Hu, Youzhong Wan
exaly  

Anti-Sf3b1

Hybridoma and Hybridomics, 2003
openaire   +1 more source

Uveal Melanomas with SF3B1 Mutations

Ophthalmology, 2016
Serdar Yavuzyigitoglu, Anna E. Koopmans, Robert M. Verdijk, Jolanda Vaarwater, Bert Eussen, Alice van Bodegom, Dion Paridaens, Emine Kiliç, Annelies de Klein   +8 more
openaire   +1 more source

Pan-cancer analysis identifies mutations in SUGP1 that recapitulate mutant SF3B1 splicing dysregulation

Proceedings of the National Academy of Sciences of the United States of America, 2020
Raúl Rabadán, Tomin E Perea-Chamblee
exaly  

Pathologic Spectrum and Molecular Landscape of Myeloid Disorders Harboring SF3B1 Mutations

American Journal of Clinical Pathology, 2021
Rong He, Mrinal M Patnaik, Jennifer Herrick   +2 more
exaly  

Pediatric Myelodysplastic Syndrome with SF3B1 Mutation.

Journal of the Association of Genetic Technologists
Patients with Fanconi Anemia (FA) have an increased risk of developing myeloid malignancies, which often precede the diagnosis of FA. We describe a patient with non-specific clinical findings diagnosed with myelodysplastic syndrome (MDS) at 17 years of age.
Britt, Boles, Matthew, Shiel, Juli-Anne, Gardner, Joanna L, Conant   +3 more
openaire   +1 more source