Results 211 to 220 of about 19,190 (266)

Impact of Cancer-Associated Mutations in Hsh155/SF3b1 HEAT Repeats 9-12 on pre-mRNA Splicing inSaccharomyces cerevisiae

, 2020
Harpreet Kaur, Brent Groubert, Joshua C. Paulson, Sarah D. McMillan, Aaron A. Hoskins   +4 more
openalex   +1 more source

Structural screening and molecular simulation identify potential ligands against the K700E hot spot variant and functional pockets of SF3B1 to modulate splicing in myelodysplastic syndrome

Heliyon
Myelodysplastic syndrome (MDS), a blood disorder with ineffective hematopoiesis and risk of transformation to acute myeloid leukemia, is characterized by recurring cytogenetic and molecular alterations.
Rolando García, Murat Atis, Andrew Cox, Prasad Koduru   +3 more
doaj  

Abstract 4654: Hotspot mutations in the core spliceosomal protein SF3B1 promote breast tumorigenesis

, 2019
Bo Liu, Michelle Ki, Omar Abdel‐Wahab, Sarat Chandarlapaty   +3 more
openalex   +1 more source

SF3B1 Mutations and Not TP53 Are Associated with Poor Outcomes in Patients with Del(5q) Myelodysplastic Syndromes (MDS)

, 2020
Onyee Chan, Najla Al Ali, David A. Sallman, Eric Padron, Jeffrey E. Lancet, Rami S. Komrokji   +5 more
openalex   +1 more source

Classification of Myelodysplastic, Myeloproliferative, and Myelodysplastic/Myeloproliferative Neoplasms: The Past, Present, and Future. [PDF]

Am J Hematol
Arber DA, Orazi A.
europepmc   +1 more source

Clinical and functional significance of circular RNAs in cytogenetically normal AML [PDF]

, 2020
al., et, Papaioannou, Dimitrios, Uy, Geoffrey L.   +2 more
core   +1 more source

Response to luspatercept can be predicted and improves overall survival in the real-life treatment of LR-MDS. [PDF]

Hemasphere
Consagra A, Lanino L, Al Ali NH, Aguirre L, Xie Z, Chan O, Andreossi G, Raddi MG, Rigodanza L, Sanna A, Mattiuz G, Tofacchi E, Amato C, Tanturli M, De Pourcq S, Walker A, Kuykendall A, Lancet J, Padron E, Sallman DA, Restuccia F, Perego A, Ubezio M, Fattizzo B, Riva M, Maggioni G, Campagna A, Della Porta MG, Santini V, Komrokji RS.   +29 more
europepmc   +1 more source

Digital PCR-based genetic profiling from vitreous fluid as liquid biopsy for primary uveal melanoma: a proof-of-concept study. [PDF]

J Exp Clin Cancer Res
Nell RJ, Versluis M, Menger NV, Gelmi MC, Vu THK, Verdijk RM, Luyten GPM, Jager MJ, van der Velden PA.   +8 more
europepmc   +1 more source

Analysis of the differences in immune indexes of common gene mutations and 5q- chromosome karyotype mutations in MDS. [PDF]

Discov Oncol
Zheng H, Meng Z, Zhang L, Li L.
europepmc   +1 more source

Successful Treatment of Anemia With Ringed Sideroblasts Induced by Antidepressants Through Vitamin B6 Supplementation and Discontinuation of Antidepressants. [PDF]

Case Rep Hematol
Nakao S, Nakaseko C, Ohwada C, Kirito K, Shibamiya A, Tanaka A, Watanabe R, Shimizu N.   +7 more
europepmc   +1 more source