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From 1 January 2013 to 31 December 2023 a total of 6,601 cases of SFTS were reported in Xinyang. The incidence of SFTS exhibits evident seasonality, commencing from March and gradually escalating from April, peaking between May and June, followed by a decline with reduced incidence after October.
Quanman Hu +9 more
wiley +1 more source
Cross-genotype protection of live-attenuated vaccine candidate for severe fever with thrombocytopenia syndrome virus in a ferret model [PDF]
Severe fever with thrombocytopenia syndrome (SFTS) virus (SFTSV) is an emerging tick-borne virus classified within the Banyangvirus genus. SFTS disease has been reported throughout East Asia since 2009 and is characterized by high fever, thrombocytopenia,
Brennan, Benjamin +7 more
core +1 more source
Severe fever with thrombocytopenia syndrome (SFTS) is a life-threatening infectious disease caused by a novel phlebovirus, SFTS virus (SFTSV). Currently, there is no vaccine or antiviral available and the viral pathogenesis remains largely unknown.
Yun-Jia Ning +12 more
doaj +1 more source
Analysis of Gene Differences Between F and B Epidemic Lineages of Bandavirus Dabieense
The prevalence of SFTS is becoming increasingly widespread and is expected to become a significant security issue. The article discusses the prevalence regions and genetic differences in two SFTSV lineages, so as to provide a scientific data basis for ...
Wenzhou Ma +6 more
doaj +1 more source
Seroprevalence of severe fever with thrombocytopenia syndrome virus in medium-sized wild mammals in Miyazaki, Japan. [PDF]
application/pdfSevere fever with thrombocytopenia syndrome (SFTS) is a fatal emerging tick-borne zoonotic disease caused by the SFTS virus (SFTSV). SFTSV infection in humans and companion animals is a matter of concern in endemic areas.
10359995 +69 more
core
A working model of host protein GADD45A regulation of PPRV replication. During PPRV infection, the viral protein V forms a complex with GADD45A in the cytoplasm. GADD45A interacts with TBK1 and inhibits its expression. Similarly, V also interacts with TBK1 and inhibits TBK1 expression.
Haiyan Ding +9 more
wiley +1 more source
ABSTRACT Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease with significant mortality risks. This study evaluated the predictive value of the lactate dehydrogenase/albumin to urea ratio (LAU) for lethal outcomes in SFTS patients.
Ruihua Zhang +10 more
wiley +1 more source
Engineered Biomolecular Condensates Limit Tobacco Mosaic Virus Accumulation and Symptom Development
Artificial biomolecular condensates were designed to target engineered tobacco mosaic virus using the MS2‐MCP tagging system. ABSTRACT Artificial condensates formed by liquid–liquid phase separation (LLPS) have been extensively studied in the field of synthetic biology for their ability to control cellular functions in a reversible and tunable manner ...
Alyssa M. Stanfield, Jared P. May
wiley +1 more source
Development of recombinant vaccine against Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) [PDF]
학위논문 (석사) -- 서울대학교 대학원 : 의과대학 의과학과, 2020. 8. 조남혁.Severe Fever with Thrombocytopenia Syndrome virus (SFTSV) is an emerging tick-borne virus which causes SFTS disease with a mortality rate of 5-27% in humans.
최훈철
core
Viral infection triggers monomerization and nuclear translocation of the salicylic acid receptor NONEXPRESSOR OF PATHOGENESIS‐RELATED GENES1 (NPR1) to activate pathogenesis‐related gene expression. Nevertheless, viruses have developed one or more proteins to target NPR1 and impair its functionality through mechanisms such as inducing its degradation ...
Xue Jiang +9 more
wiley +1 more source

