Results 81 to 90 of about 3,481 (207)

SFTSV nucleoprotein mediates DNA sensor cGAS degradation to suppress cGAS-dependent antiviral responses

Microbiology Spectrum
Cyclic GMP-AMP synthase (cGAS) is an important DNA pattern recognition receptor that senses double-stranded DNA derived from invading pathogens or self DNA in cytoplasm, leading to an antiviral interferon response.
Ze-zheng Jiang, Min Chu, Li-na Yan, Wen-kang Zhang, Bang Li, Jiao Xu, Zhong-xin Zhao, Hui-Ju Han, Chuan-min Zhou, Xue-jie Yu   +9 more
doaj   +1 more source

A One Health Assessment of Tick and Tick‐Borne Pathogen Diversity and Zoonotic Risk in Hubei Province, Central China

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Ticks and tick‐borne pathogens (TBPs) threaten livestock productivity and public health worldwide, and climate–land‐use change is expanding vector habitats, elevating tick‐borne disease risk. However, TBP diversity and risk in Hubei Province, central China, remain insufficiently defined within a One Health framework.
Qian Chen, Ning-wei Ma, Shi-ying Zhu, Dong-fang Li, Xiao-yan Lei, Zi-qian Zhou, Fen Du, Lan He, Jun-long Zhao, Ruofeng Yan   +9 more
wiley   +1 more source

Recent Advances in Lateral Flow Immunoassay for Rapid Diagnosis of Viral Diseases

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Viral diseases are a major threat to human and animal health, as illustrated by recent pandemics like COVID‐19 and African swine fever (ASF). Timely, accurate detection of viral infections is critical for effective disease control. Among diverse diagnostic techniques, lateral flow immunoassay (LFIA) has become a widely used on‐site testing tool, owing ...
Quanyu Ren, Yan Wang, Haoyuan Ma, Jialiang Xie, Jianyou Jin, Rumeng Tian, Hao Yu, Xu Gao, Nanhua Chen   +8 more
wiley   +1 more source

Analysis of Gene Differences Between F and B Epidemic Lineages of Bandavirus Dabieense

Microorganisms
The prevalence of SFTS is becoming increasingly widespread and is expected to become a significant security issue. The article discusses the prevalence regions and genetic differences in two SFTSV lineages, so as to provide a scientific data basis for ...
Wenzhou Ma, Yujia Hao, Chengcheng Peng, Duo Zhang, Yuge Yuan, Pengpeng Xiao, Nan Li   +6 more
doaj   +1 more source

Development of recombinant vaccine against Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) [PDF]

, 2020
학위논문 (석사) -- 서울대학교 대학원 : 의과대학 의과학과, 2020. 8. 조남혁.Severe Fever with Thrombocytopenia Syndrome virus (SFTSV) is an emerging tick-borne virus which causes SFTS disease with a mortality rate of 5-27% in humans.
최훈철
core  

Cross-genotype protection of live-attenuated vaccine candidate for severe fever with thrombocytopenia syndrome virus in a ferret model [PDF]

, 2019
Severe fever with thrombocytopenia syndrome (SFTS) virus (SFTSV) is an emerging tick-borne virus classified within the Banyangvirus genus. SFTS disease has been reported throughout East Asia since 2009 and is characterized by high fever, thrombocytopenia,
Brennan, Benjamin, Choi, Young Ki, Choi, Younho, Jung, Jae U., Kim, Young-Il, Park, Su-Jin, Yu, Kwang-Min, Yu, Min-Ah   +7 more
core   +1 more source

Role of Atypical MAPK p38 Signaling in the Progression of Influenza A‐Induced Acute Lung Injury

The FASEB Journal, Volume 39, Issue 18, 30 September 2025.
Genetic block of TAB1‐dependent atypical p38 signaling reduces weight loss and early‐phase pathological markers in an influenza A virus‐induced lung injury model. ABSTRACT Mitogen‐activated protein kinase (MAPK) p38 plays a key role in driving the pathology of acute lung injury (ALI), but effective therapeutic targeting remains elusive.
Jeremy C. Burton, Denise L. Fahey, Fredejah T. Royer, Yin Zhu, Kaori Sakamoto, Duo Zhang, Wendy T. Watford, Neil J. Grimsey   +7 more
wiley   +1 more source

Interferon-γ-Directed Inhibition of a Novel High-Pathogenic Phlebovirus and Viral Antagonism of the Antiviral Signaling by Targeting STAT1

Frontiers in Immunology, 2019
Severe fever with thrombocytopenia syndrome (SFTS) is a life-threatening infectious disease caused by a novel phlebovirus, SFTS virus (SFTSV). Currently, there is no vaccine or antiviral available and the viral pathogenesis remains largely unknown.
Yun-Jia Ning, Qiong Mo, Qiong Mo, Kuan Feng, Kuan Feng, Yuan-Qin Min, Mingyue Li, Dianhai Hou, Cheng Peng, Xin Zheng, Fei Deng, Zhihong Hu, Hualin Wang   +12 more
doaj   +1 more source

Serological and molecular surveillance of Orientia tsutsugamushi in scrub typhus patients and coinfection of Huaiyangshan banyangvirus [PDF]

, 2020
학위논문 (박사) -- 서울대학교 대학원 : 의과대학 의과학과, 2020. 8. 조남혁.1. Introduction: Scrub typhus is a mite-borne infectious disease caused by Orientia tsutsugamushi. Huaiyangshan banyangvirus (formerly Severe fever with thrombocytopenia syndrome virus (SFTSV)) is a tick ...
Nguyen Thi Hai Yen
core  

Viral discovery and diversity in trypanosomatid protozoa with a focus on relatives of the human parasite Leishmania. [PDF]

, 2018
Knowledge of viral diversity is expanding greatly, but many lineages remain underexplored. We surveyed RNA viruses in 52 cultured monoxenous relatives of the human parasite <i>Leishmania</i> ( <i>Crithidia</i> and <i> ...
Akopyants, N.S., Beverley, S.M., Butenko, A., d'Avila-Levy, C.M., Dobson, D.E., Fasel, N., Frolov, A.O., Grybchuk, D., Konovalovas, A., Kostygov, A.Y., Kulich, P., Lukeš, J., Lye, L.F., Moravcová, J., Plevka, P., Rogozin, I.B., Serva, S., Votýpka, J., Yurchenko, V., Zangger, H.   +19 more
core   +1 more source