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Seroprevalence of severe fever with thrombocytopenia syndrome virus in medium-sized wild mammals in Miyazaki, Japan. [PDF]

, 2022
application/pdfSevere fever with thrombocytopenia syndrome （SFTS） is a fatal emerging tick-borne zoonotic disease caused by the SFTS virus （SFTSV）. SFTSV infection in humans and companion animals is a matter of concern in endemic areas.
10359995, 10359995, 1864, 20229678, 20506084, 20506084, 20753833, 20753833, 20811706, 20811706, 21827, 21827, 21829, 24382, 33891, 33891, 34096, 34096, 34097, 34097, 34098, 34098, 34100, 34102, 70458280, 70458280, 90633264, Irie, Takao, Irie, Takao, Kaneko, Chiho, Kaneko, Chiho, Mekata, Hirohisa, Mekata, Hirohisa, Misawa, Naoaki, Okabayashi, Tamaki, Okabayashi, Tamaki, Putu, Eka Sudaryatma, Umeki, Kazumi, Umekita, Kunihiko, Umekita, Kunihiko, Yamada, Kentaro, Yamada, Kentaro, イリエ, タカオ, イリエ, タカオ, ウメキ, カズミ, ウメキタ, クニヒコ, ウメキタ, クニヒコ, オカバヤシ, タマキ, オカバヤシ, タマキ, カネコ, チホ, カネコ, チホ, プトゥ, エカ スダルヤトマ, プトゥ, エカ スダルヤトマ, ミサワ, ナオアキ, メカタ, ヒロヒサ, ヤマダ, ケンタロウ, ヤマダ, ケンタロウ, 三澤, 尚明, 入江, 隆夫, 入江, 隆夫, 兼子, 千穂, 兼子, 千穂, 山田, 健太郎, 山田, 健太郎, 岡林, 環樹, 岡林, 環樹, 梅北, 邦彦, 梅北, 邦彦, 梅木, 一美, 目堅, 博久   +69 more
core  

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

Small Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source

Distribution of Tick Vectors of Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) Collected from Four Environments in Jeju

Korean Journal of Clinical Laboratory Science, 2020
The distribution of ticks and severe fever with thrombocytopenia syndrome virus (SFTSV) pathogens were investigated by collecting ticks from March to November 2018 in four environments (grass fields, copses, mountain roads, and tombs) in Jeju.
Kyoung A Chung, Hyeon Je Song, Hyeok Jae Lee, Chul Park, Min Yeung Seo   +4 more
doaj   +1 more source

Pathogenicity of severe fever with thrombocytopenia syndrome virus in mice regulated in type I interferon signaling

Laboratory Animal Research, 2020
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging zoonotic disease, which causes high fever, thrombocytopenia, and death in humans and animals in East Asian countries. The pathogenicity of SFTS virus (SFTSV) remains unclear.
Seok-Chan Park, Jun Young Park, Jin Young Choi, Sung-Geun Lee, Seong Kug Eo, Jae-Ku Oem, Dong-Seob Tark, Myungjo You, Do-Hyeon Yu, Joon-Seok Chae, Bumseok Kim   +10 more
doaj   +1 more source

Unraveling the Underlying Interaction Mechanism Between Dabie bandavirus and Innate Immune Response

Frontiers in Immunology, 2021
The genus Bandavirus consists of seven tick-borne bunyaviruses, among which four are known to infect humans. Dabie bandavirus, severe fever with thrombocytopenia syndrome virus (SFTSV), poses serious threats to public health worldwide.
Chuan-min Zhou, Chuan-min Zhou, Xue-jie Yu   +2 more
doaj   +1 more source

Vascular Leak and Hypercytokinemia Associated with Severe Fever with Thrombocytopenia Syndrome Virus Infection in Mice [PDF]

, 2019
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging viral hemorrhagic fever (VHF) endemic to China, South Korea, Japan, and Vietnam. Here we characterize the pathogenesis and natural history of disease in IFNAR-/- mice challenged with the ...
Dagley, Ashley, Furuta, Yousuke, Gowen, Brian B., Hickerson, Brady T., Hurst, Brett L., Komeno, Takashi, Kurz, Jacqueline P., Steiner, Thomas, Van Wettere, Arnaud J., Westover, Jonna B., Wülfroth, Petra   +10 more
core   +2 more sources

Integration of SFTSV Viral Load, Age, and Double‐Negative B‐Cells as Prognostic Biomarkers for Severe Fever With Thrombocytopenia Syndrome Outcomes

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Background Severe fever with thrombocytopenia syndrome (SFTS) is a tick‐borne viral illness with high mortality, yet early risk stratification remains challenging. Recent evidence suggests that B‐cell dysregulation contributes to disease severity. Methods A cohort of 168 patients with confirmed SFTS was retrospectively analyzed. Flow cytometry was used
Wei Wei, Qian Tai, Heng Liu, Rujia Chen, Yun Wang, Ting Wang, Renren Ouyang, Shiji Wu, Feng Wang, Hongyan Hou, Poorani Gurumallesh   +10 more
wiley   +1 more source

Distribution of Ticks and Prevalence of Tick‐Borne Pathogens in Multiple Regions of China

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Ticks and tick‐borne pathogens pose significant threats to livestock and public health. While tick occurrences have been reported in China, systematic assessments of pathogen risk factors across diverse hosts and regions remain limited. This study investigated tick distribution, prevalence, and associated pathogen infections across seven sampling sites
Yichen Jian, Shunli Lu, Dongliang Li, Yifei Liu, Sumei Zhang, Longxian Zhang, Senyang Li, Fuchun Jian, Ruofeng Yan   +8 more
wiley   +1 more source

Identification and characterization of three monoclonal antibodies targeting the SFTSV glycoprotein and displaying a broad spectrum recognition of SFTSV-related viruses

PLOS Neglected Tropical Diseases
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a novel tick-borne viral pathogen that causes severe fever with thrombocytopenia syndrome (SFTS). The disease was initially reported in central and eastern China, then later in Japan and South Korea, with a mortality rate of 13–30%.
Xiaoli Wu, Abulimiti Moming, Yanfang Zhang, Zhiying Wang, Tao Zhang, Liyan Fu, Jin Qian, Jun Ni, Sijing Hu, Shuang Tang, Xin Zheng, Hualin Wang, Shu Shen, Fei Deng   +13 more
openaire   +2 more sources

The immunogenicity and protection efficacy evaluation of mRNA vaccine candidate for severe fever with thrombocytopenia syndrome in mice.

PLoS Neglected Tropical Diseases
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne viral pathogen that causes Severe fever with thrombocytopenia syndrome (SFTS) in humans with a high fatality rate.
Da-Eun Jeong, Jack Yoon, Baek Kim, Jun-Gu Kang   +3 more
doaj   +1 more source