Results 51 to 60 of about 2,383 (169)

Molecular genomic characterization of tick- and human-derived severe fever with thrombocytopenia syndrome virus isolates from South Korea.

PLoS Neglected Tropical Diseases, 2017
BackgroundSevere fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne viral disease caused by the SFTS virus (SFTSV) from Bunyaviridae that is endemic in East Asia.
Seok-Min Yun, Su-Jin Park, Sun-Whan Park, WooYoung Choi, Hye Won Jeong, Young-Ki Choi, Won-Ja Lee   +6 more
doaj   +1 more source

Identification of surfactin as an anti-severe fever with thrombocytopenia syndrome virus multi-target compound extracted from the culture broth of marine microbes

Frontiers in Virology, 2023
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne virus first identified in China in 2011 and later reported in other Asian countries.
Shuzo Urata, Shuzo Urata, Jun Takouda, Yoshihiro Watanabe, Miako Sakaguchi, Yasuteru Sakurai, Yasuteru Sakurai, Yuki Inahashi, Masato Iwatsuki, Jiro Yasuda, Jiro Yasuda, Yoshimasa Tanaka, Kohsuke Takeda   +12 more
doaj   +1 more source

Host‐Directed Antiviral Activity of SB2960 Through Selective Induction and Remodeling of Stress Granules

Advanced Science, Volume 13, Issue 12, 27 February 2026.
Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun, Sumin Son, JinAh Lee, Minha Lee, Meehyun Ko, Songrui Zhao, Ju Hee Kim, Kannan Vaithegi, Ji Hoon Kwon, Jung Ho Lee, Sangeun Jeon, Dawon Yi, Peng Zou, Seungtaek Kim, Seung Bum Park   +14 more
wiley   +1 more source

Identification and characterization of three monoclonal antibodies targeting the SFTSV glycoprotein and displaying a broad spectrum recognition of SFTSV-related viruses

PLOS Neglected Tropical Diseases
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a novel tick-borne viral pathogen that causes severe fever with thrombocytopenia syndrome (SFTS). The disease was initially reported in central and eastern China, then later in Japan and South Korea, with a mortality rate of 13–30%.
Xiaoli Wu, Abulimiti Moming, Yanfang Zhang, Zhiying Wang, Tao Zhang, Liyan Fu, Jin Qian, Jun Ni, Sijing Hu, Shuang Tang, Xin Zheng, Hualin Wang, Shu Shen, Fei Deng   +13 more
openaire   +2 more sources

The immunogenicity and protection efficacy evaluation of mRNA vaccine candidate for severe fever with thrombocytopenia syndrome in mice.

PLoS Neglected Tropical Diseases
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne viral pathogen that causes Severe fever with thrombocytopenia syndrome (SFTS) in humans with a high fatality rate.
Da-Eun Jeong, Jack Yoon, Baek Kim, Jun-Gu Kang   +3 more
doaj   +1 more source

Pathogenicity of severe fever with thrombocytopenia syndrome virus in mice regulated in type I interferon signaling

Laboratory Animal Research, 2020
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging zoonotic disease, which causes high fever, thrombocytopenia, and death in humans and animals in East Asian countries. The pathogenicity of SFTS virus (SFTSV) remains unclear.
Seok-Chan Park, Jun Young Park, Jin Young Choi, Sung-Geun Lee, Seong Kug Eo, Jae-Ku Oem, Dong-Seob Tark, Myungjo You, Do-Hyeon Yu, Joon-Seok Chae, Bumseok Kim   +10 more
doaj   +1 more source

Cyclophilin A causes severe fever with thrombocytopenia syndrome virus-induced cytokine storm by regulating mitogen-activated protein kinase pathway

Frontiers in Microbiology, 2022
IntroductionSevere fever with thrombocytopenia syndrome (SFTS) has become a global threat to public health since its first report in China in 2009. However, the pathogenesis of SFTS virus (SFTSV) in humans remains unclear.
Huaying Huang, Huaying Huang, Ke Jin, Ke Ouyang, Zhengyi Jiang, Zhan Yang, Nannan Hu, Yan Dai, Yaqin Zhang, Qian Zhang, Ying Han, Jie Zhao, Hong Lin, Chunhui Wang, Chunyan Wang, Xuewei Sun, Dafeng Lu, Jin Zhu, Jun Li   +18 more
doaj   +1 more source

Insights on the phenology of the Asian longhorned tick (Haemaphysalis longicornis) using stored lipids

Insect Science, Volume 33, Issue 1, Page 396-406, February 2026.
Lipid analysis of field‐collected ticks unveiled a complex population structure and supports the potential for several stages to overwinter. Abstract The seasonality of Haemaphysalis longicornis in the United States comprises overlapping life stages in the spring and summer.
Matthew Bickerton, Julia González, Alvaro Toledo   +2 more
wiley   +1 more source

Portable RT-LAMP Platform for Rapid Point-of-Care Detection for SFTSV. [PDF]

J Microbiol Biotechnol
Severe Fever with Thrombocytopenia Syndrome virus (SFTSV) is a tick-borne pathogen associated with high mortality, particularly among the elderly, and poses a significant public health threat in East Asia's rural areas. Improved diagnostic approaches are crucial for effective disease management in resource-limited settings.
Lee GC, Kim BK, Batool S, Park JH, Min SC, Lee JR, Lee DG, An SH, Jain A, Kim DH, Lee HJ, Choi YK, Song MS, Baek YH.   +13 more
europepmc   +3 more sources

RNAi Regulator C3PO Promotes Arbovirus Infection in Insect Vectors

Advanced Science, Volume 13, Issue 4, 19 January 2026.
RNA interference (RNAi) is vital for eukaryotes to defend against virus infection. The C3PO complex takes part in RNAi but its role in regulating viral infection remains unclear. This work finds that insect C3PO facilitates arbovirus replication by degrading precursors of miRNAs, especially miR‐971‐3p.
Yan Xiao, Tianyu Guan, Qianfeng Xia, Chen Chen, Qian Wang, Lan Luo, Hong Lu, Feng Cui   +7 more
wiley   +1 more source