Results 51 to 60 of about 3,481 (207)

SFTSV Gn‐Head mRNA vaccine confers efficient protection against lethal viral challenge

Journal of Medical Virology, 2023
AbstractSevere fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick‐borne virus, causing thrombocytopenia and hemorrhagic fever, with a fatality rate ranging from 12% to 30%. SFTSV possesses Gn and Gc glycoproteins, which are responsible for host cell receptor attachment and membrane fusion, respectively, to infect host cells. We have
Dokyun, Kim, Chih-Jen, Lai, Inho, Cha, Seokmin, Kang, Wan-Shan, Yang, Younho, Choi, Jae U, Jung   +6 more
openaire   +2 more sources

Viral shedding pattern of severe fever with thrombocytopenia syndrome virus in severely ill patients: A prospective, Multicenter cohort study

Heliyon
Background: Severe fever with thrombocytopenia syndrome (SFTS) is spreading rapidly in Asia. The pathway of SFTS virus shedding from patient and specific use of personal protective equipments (PPEs) against viral transmission have rarely been reported ...
Li-Fen Hu, Ting-Ting Bian, Qiang Chen, Meng-Yu Liu, Jia-Jia Li, Qin-Xiang Kong, Jian-Kang Zhang, Jin Wu, Jun Cheng, Rui Yu, Yan-Qin Qiu, Yu-Feng Gao, Guo-Sheng Chen, Ying Ye, Ting Wu, Jia-Bin Li   +15 more
doaj   +1 more source

Fine mapping epitope on Glycoprotein-Gn from Severe Fever with Thrombocytopenia Syndrome Virus.

PLoS ONE, 2021
Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) was recently identified as a tick-borne pathogen that threat to human health. Since 2010, many countries including China, South Korea, and Japan have reported Human SFTS caused by SFTSV infection.
Abulimiti Moming, Shen Shi, Shu Shen, Jie Qiao, Xihong Yue, Bo Wang, Juntao Ding, Zhihong Hu, Fei Deng, Yujiang Zhang, Surong Sun   +10 more
doaj   +1 more source

Severe fever with thrombocytopenia syndrome phlebovirus non-structural protein activates TPL2 signalling pathway for viral immunopathogenesis [PDF]

, 2019
Severe fever with thrombocytopenia syndrome phlebovirus (SFTSV), listed in the World Health Organization Prioritized Pathogens, is an emerging phlebovirus with a high fatality .
Brennan, Benjamin, Chen, Sally B, Choi, Young-Ki, Choi, Younho, Foo, Suan-Sin, Jung, Jae U, Lee, Jong-Soo, Lee, Won-Ja, Li, Wenhui, Park, Su-Jin, Pudupakam, Raghavendra Sumanth, Shin, Woo-Jin, Sun, Yinyan, Tsichlis, Philip N, Yoo, Ji-Seung   +14 more
core   +1 more source

High Seroprevalence of Severe Fever with Thrombocytopenia Syndrome Virus Infection among the Dog Population in Thailand

Viruses, 2023
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne zoonotic disease caused by the SFTS virus (SFTSV). In Thailand, three human cases of SFTS were reported in 2019 and 2020, but there was no report of SFTSV infection in animals ...
Keita Ishijima, Thanmaporn Phichitraslip, Nattakarn Naimon, Preeyaporn Ploypichai, Benyapa Kriebkajon, Torntun Chinarak, Jirasin Sridaphan, Anamika Kritiyakan, Noppadol Prasertsincharoen, Sathaporn Jittapalapong, Kanate Tangcham, Worawut Rerkamnuaychoke, Yudai Kuroda, Masakatsu Taira, Kango Tatemoto, Eunsil Park, Milagros Virhuez-Mendoza, Yusuke Inoue, Michiko Harada, Tsukasa Yamamoto, Ayano Nishino, Aya Matsuu, Ken Maeda   +22 more
doaj   +1 more source

Tick‐Tac‐Foe: When Ticks, Trade, and Zoonotic Pathogens Align in African Wet Meat Markets

Public Health Challenges, Volume 5, Issue 2, June 2026.
ABSTRACT Zoonotic diseases account for over ∼60% of infectious diseases and present a significantly growing fatality threat in Africa. Live and wet markets (LWMs) in Africa function as key economic venues that support human livelihoods through social interaction and trade in food stuff, including meat and other animal‐based products.
Allen Takudzwa Munaro
wiley   +1 more source

Early Tick Species Identification Using Eschar‐Based PCR to Guide Presymptomatic Risk Assessment in Tick‐Borne Diseases

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT In endemic regions where simultaneous larval tick bites frequently occur, early identification of tick species from eschar lesions may substantially influence presymptomatic clinical triage. We report a 78‐year‐old woman who was found after approximately 24 h of wandering, presenting with multiple clustered eschars on the lower extremities and
Makoto Kondo, Koji Habe, Keiichi Yamanaka   +2 more
wiley   +1 more source

Animal Model of Severe Fever With Thrombocytopenia Syndrome Virus Infection

Frontiers in Microbiology, 2022
Severe fever with thrombocytopenia syndrome (SFTS), an emerging life-threatening infectious disease caused by SFTS bunyavirus (SFTSV; genus Bandavirus, family Phenuiviridae, order Bunyavirales), has been a significant medical problem.
Jiawen Sun, Jiawen Sun, Yuan-Qin Min, Yuan-Qin Min, Yunjie Li, Xiulian Sun, Xiulian Sun, Fei Deng, Fei Deng, Hualin Wang, Hualin Wang, Yun-Jia Ning, Yun-Jia Ning   +12 more
doaj   +1 more source

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source

Severe fever with thrombocytopenia syndrome virus induces lactylation of m6A reader protein YTHDF1 to facilitate viral replication

EMBO Reports
Severe fever with thrombocytopenia syndrome virus (SFTSV), an emerging infectious pathogen with a high fatality rate, is an enveloped tripartite segmented single-stranded negative-sense RNA virus.
Bingxin Liu, Xiaoyan Tian, Linrun Li, Rui Zhang, Jing Wu, Na Jiang, Meng Yuan, Deyan Chen, Airong Su, Shijie Xu, Zhiwei Wu   +10 more
doaj   +1 more source