Results 61 to 70 of about 3,280 (212)
The phylogenetic tree was constructed by using the Neighbor-Joining method with the MEGA5.1 software. The reliability values indicated at the branch nodes were determined using 1,000 bootstrap replications.
Xiaochen Wang (235611) +18 more
core +1 more source
This review summarises the detection methods for severe fever with thrombocytopenia syndrome virus based on CRISPR platforms. (A) CRISPR with fluorescent reporter. (B) CRISPR with lateral flow test strip. (C) CRISPR with DNAzyme. (D) Digital CRISPR. (E) CRISPR with single micro‐ring resonator biosensor. (F) self‐amplifying signal amplification strategy
Junhu Wang +8 more
wiley +1 more source
Integrated transcriptome profiling in THP-1 macrophages infected with bunyavirus SFTSV
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne bunyavirus that causes an emerging hemorrhagic fever termed SFTS with high mortality. However, knowledge of SFTSV-host interactions is largely limited. Here, we performed a global transcriptome analysis of mRNAs and lncRNAs in THP-1 macrophages infected with SFTSV for 24 and 48 h.
Jia-Min, Yan +4 more
openaire +2 more sources
SFTSV NSs protein is a tick antiviral RNAi response suppressor. [PDF]
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne phenuivirus causing high mortality in humans. While the nonstructural protein NSs is dispensable for replication in interferon-deficient mammalian cells, we demonstrate ...
Fares M +14 more
europepmc +2 more sources
Given the central role of protein structures in RNA virus biology, the RNA viral protein structure database (RVPSD, https://virus.9itsg.net) integrates taxonomic classification, viral nucleotide and protein sequences, functional annotations, and predicted three‐dimensional protein structures.
Qiangzhen Yang +8 more
wiley +1 more source
Molecular detection of Rickettsia, Hepatozoon, Ehrlichia and SFTSV in goat ticks
Ticks are vectors of various pathogens to people, livestock, companion animals and wildlife. We describe here the ticks found on goats in Anhui province of China and the results of molecular studies on six tick-borne pathogens they might harbor. Among 125 ticks collected (119 Haemaphysalis longicornis, n = 119; Rhipicephalus microplus, n = 6), we ...
Jing, Li +6 more
openaire +3 more sources
Macropinocytosis inhibitor EIPA did not reduce SFTSV infection.
Macropinocytosis inhibitor EIPA did not reduce SFTSV infection.
Jiajia Li (184267) +11 more
core +1 more source
ABSTRACT Early differentiation of severe fever with thrombocytopenia syndrome (SFTS) and hemorrhagic fever with renal syndrome (HFRS) remains difficult in endemic settings. In this single‐center retrospective comparative study, we analyzed admission‐time demographic, clinical, and laboratory data from 330 hospitalized patients with laboratory‐confirmed
Ruize Ma +7 more
wiley +1 more source
Genetic evolution and codon usage mode of SFTSV
Introduction Severe fever with thrombocytopenia syndrome virus (SFTSV), first identified in Henan Province, China (2009), has since been detected in 26 Chinese provinces and remains a significant public health threat.
Zhang, Yuhan +8 more
openaire +2 more sources
The phylogenetic tree was constructed by the maximum likelihood method with the MEGA5 software. The reliability values indicated at the branch nodes were determined using 1,000 bootstrap replications.
Jia Su (128774) +9 more
core +1 more source

