Results 61 to 70 of about 3,481 (207)

Host‐Directed Antiviral Activity of SB2960 Through Selective Induction and Remodeling of Stress Granules

Advanced Science, Volume 13, Issue 12, 27 February 2026.
Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun, Sumin Son, JinAh Lee, Minha Lee, Meehyun Ko, Songrui Zhao, Ju Hee Kim, Kannan Vaithegi, Ji Hoon Kwon, Jung Ho Lee, Sangeun Jeon, Dawon Yi, Peng Zou, Seungtaek Kim, Seung Bum Park   +14 more
wiley   +1 more source

Severe fever with thrombocytopenia syndrome virus infection during pregnancy in C57/BL6 mice causes fetal damage.

PLoS Neglected Tropical Diseases, 2020
BackgroundSevere fever with thrombocytopenia syndrome virus (SFTSV) is a novel tick-borne phlebovirus, which is listed in the most dangerous pathogens by the World Health Organization, and has 12-30% fatality rates.
Rui Chen, Zeng-Qiang Kou, Xiao-Rui Wang, Shu-Han Li, Hai-Lu Zhang, Zi-Wei Liu, Dong Cheng, Zhi-Yu Wang, Xue-Jie Yu, Hong-Ling Wen   +9 more
doaj   +1 more source

Modeling Severe Fever with Thrombocytopenia Syndrome Virus Infection in Golden Syrian Hamsters: Importance of STAT2 in Preventing Disease and Effective Treatment with Favipiravir [PDF]

, 2017
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease endemic in parts of Asia. The etiologic agent, SFTS virus (SFTSV; family Bunyaviridae, genus Phlebovirus) has caused significant morbidity and mortality in China, South ...
Conrad, Bettina L., Furuta, Yousuke, Gowen, Brian B., Hickerson, Brady T., Jung, Kie-Hoon, Li, Rong, Miao, Jinxin, Nielson, Skot, Rigas, Johanna D., Van Wettere, Arnaud J., Wang, Zhongde, Westover, Jonna B.   +11 more
core   +2 more sources

Insights on the phenology of the Asian longhorned tick (Haemaphysalis longicornis) using stored lipids

Insect Science, Volume 33, Issue 1, Page 396-406, February 2026.
Lipid analysis of field‐collected ticks unveiled a complex population structure and supports the potential for several stages to overwinter. Abstract The seasonality of Haemaphysalis longicornis in the United States comprises overlapping life stages in the spring and summer.
Matthew Bickerton, Julia González, Alvaro Toledo   +2 more
wiley   +1 more source

SFTSV Prevalence in Ticks and Livestock in an SFTSV-Endemic Area in Central China

Pathogens
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne bunyavirus that causes a severe viral hemorrhagic fever (SFTS), with a very high case mortality rate, expanding epidemic areas, and increasing incidence. Due to the lack of an effective drug or vaccine for SFTS, reducing the incidence and mortality of SFTS primarily ...
Hui-Ya Lu, Guan-Du Wu, Meng Peng, Li-Bang Wu, Yi-Ming Luo, Bin Xia, Dan Xiong, Xiang-Rong Qin, Fang Guo, Xue-Jie Yu   +9 more
openaire   +1 more source

A highly attenuated vaccinia virus strain LC16m8-based vaccine for severe fever with thrombocytopenia syndrome.

PLoS Pathogens, 2021
Severe fever with thrombocytopenia syndrome (SFTS) caused by a species Dabie bandavirus (formerly SFTS virus [SFTSV]) is an emerging hemorrhagic infectious disease with a high case-fatality rate.
Tomoki Yoshikawa, Satoshi Taniguchi, Hirofumi Kato, Naoko Iwata-Yoshikawa, Hideki Tani, Takeshi Kurosu, Hikaru Fujii, Natsumi Omura, Miho Shibamura, Shumpei Watanabe, Kazutaka Egawa, Takuya Inagaki, Satoko Sugimoto, Supranee Phanthanawiboon, Shizuko Harada, Souichi Yamada, Shuetsu Fukushi, Shigeru Morikawa, Noriyo Nagata, Masayuki Shimojima, Masayuki Saijo   +20 more
doaj   +1 more source

Severe Fever with Thrombocytopenia Syndrome Virus in Dogs, South Korea

Emerging Infectious Diseases, 2019
Of 103 serum samples collected from dogs in South Korea, 3 (2.9%) were positive for severe fever with thrombocytopenia syndrome virus (SFTSV) and 22 (21.4%) were positive for antibodies against SFTSV.
Jun-Gu Kang, Yoon-Kyoung Cho, Young-Sun Jo, Jeong-Byoung Chae, Young-Hoon Joo, Kyoung-Wan Park, Joon-Seok Chae   +6 more
doaj   +1 more source

Identification of surfactin as an anti-severe fever with thrombocytopenia syndrome virus multi-target compound extracted from the culture broth of marine microbes

Frontiers in Virology, 2023
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne virus first identified in China in 2011 and later reported in other Asian countries.
Shuzo Urata, Shuzo Urata, Jun Takouda, Yoshihiro Watanabe, Miako Sakaguchi, Yasuteru Sakurai, Yasuteru Sakurai, Yuki Inahashi, Masato Iwatsuki, Jiro Yasuda, Jiro Yasuda, Yoshimasa Tanaka, Kohsuke Takeda   +12 more
doaj   +1 more source

RNAi Regulator C3PO Promotes Arbovirus Infection in Insect Vectors

Advanced Science, Volume 13, Issue 4, 19 January 2026.
RNA interference (RNAi) is vital for eukaryotes to defend against virus infection. The C3PO complex takes part in RNAi but its role in regulating viral infection remains unclear. This work finds that insect C3PO facilitates arbovirus replication by degrading precursors of miRNAs, especially miR‐971‐3p.
Yan Xiao, Tianyu Guan, Qianfeng Xia, Chen Chen, Qian Wang, Lan Luo, Hong Lu, Feng Cui   +7 more
wiley   +1 more source

Molecular genomic characterization of tick- and human-derived severe fever with thrombocytopenia syndrome virus isolates from South Korea.

PLoS Neglected Tropical Diseases, 2017
BackgroundSevere fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne viral disease caused by the SFTS virus (SFTSV) from Bunyaviridae that is endemic in East Asia.
Seok-Min Yun, Su-Jin Park, Sun-Whan Park, WooYoung Choi, Hye Won Jeong, Young-Ki Choi, Won-Ja Lee   +6 more
doaj   +1 more source