Results 41 to 50 of about 2,383 (169)

Animal Model of Severe Fever With Thrombocytopenia Syndrome Virus Infection

Frontiers in Microbiology, 2022
Severe fever with thrombocytopenia syndrome (SFTS), an emerging life-threatening infectious disease caused by SFTS bunyavirus (SFTSV; genus Bandavirus, family Phenuiviridae, order Bunyavirales), has been a significant medical problem.
Jiawen Sun, Jiawen Sun, Yuan-Qin Min, Yuan-Qin Min, Yunjie Li, Xiulian Sun, Xiulian Sun, Fei Deng, Fei Deng, Hualin Wang, Hualin Wang, Yun-Jia Ning, Yun-Jia Ning   +12 more
doaj   +1 more source

Tick‐Tac‐Foe: When Ticks, Trade, and Zoonotic Pathogens Align in African Wet Meat Markets

Public Health Challenges, Volume 5, Issue 2, June 2026.
ABSTRACT Zoonotic diseases account for over ∼60% of infectious diseases and present a significantly growing fatality threat in Africa. Live and wet markets (LWMs) in Africa function as key economic venues that support human livelihoods through social interaction and trade in food stuff, including meat and other animal‐based products.
Allen Takudzwa Munaro
wiley   +1 more source

Severe fever with thrombocytopenia syndrome virus induces lactylation of m6A reader protein YTHDF1 to facilitate viral replication

EMBO Reports
Severe fever with thrombocytopenia syndrome virus (SFTSV), an emerging infectious pathogen with a high fatality rate, is an enveloped tripartite segmented single-stranded negative-sense RNA virus.
Bingxin Liu, Xiaoyan Tian, Linrun Li, Rui Zhang, Jing Wu, Na Jiang, Meng Yuan, Deyan Chen, Airong Su, Shijie Xu, Zhiwei Wu   +10 more
doaj   +1 more source

Distribution of Tick Vectors of Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) Collected from Four Environments in Jeju

Korean Journal of Clinical Laboratory Science, 2020
The distribution of ticks and severe fever with thrombocytopenia syndrome virus (SFTSV) pathogens were investigated by collecting ticks from March to November 2018 in four environments (grass fields, copses, mountain roads, and tombs) in Jeju.
Kyoung A Chung, Hyeon Je Song, Hyeok Jae Lee, Chul Park, Min Yeung Seo   +4 more
doaj   +1 more source

Mitochondrial DNA: A Key Alarmin Igniting the Inflammasome Fire in Health and Disease

Immunology, Volume 178, Issue 2, Page 218-230, June 2026.
This review illustrates how mitochondrial DNA, released under cellular stress, acts as a key alarmin that ignites innate immune sensors, particularly inflammasomes and the cGAS‐STING pathway. This paper details how this sustained “inflammasome fire” fuels the progression of diverse inflammatory diseases, including neurodegeneration and metabolic ...
Woo Hyun Park
wiley   +1 more source

Early Tick Species Identification Using Eschar‐Based PCR to Guide Presymptomatic Risk Assessment in Tick‐Borne Diseases

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT In endemic regions where simultaneous larval tick bites frequently occur, early identification of tick species from eschar lesions may substantially influence presymptomatic clinical triage. We report a 78‐year‐old woman who was found after approximately 24 h of wandering, presenting with multiple clustered eschars on the lower extremities and
Makoto Kondo, Koji Habe, Keiichi Yamanaka   +2 more
wiley   +1 more source

Severe Fever with Thrombocytopenia Syndrome Virus in Dogs, South Korea

Emerging Infectious Diseases, 2019
Of 103 serum samples collected from dogs in South Korea, 3 (2.9%) were positive for severe fever with thrombocytopenia syndrome virus (SFTSV) and 22 (21.4%) were positive for antibodies against SFTSV.
Jun-Gu Kang, Yoon-Kyoung Cho, Young-Sun Jo, Jeong-Byoung Chae, Young-Hoon Joo, Kyoung-Wan Park, Joon-Seok Chae   +6 more
doaj   +1 more source

A highly attenuated vaccinia virus strain LC16m8-based vaccine for severe fever with thrombocytopenia syndrome.

PLoS Pathogens, 2021
Severe fever with thrombocytopenia syndrome (SFTS) caused by a species Dabie bandavirus (formerly SFTS virus [SFTSV]) is an emerging hemorrhagic infectious disease with a high case-fatality rate.
Tomoki Yoshikawa, Satoshi Taniguchi, Hirofumi Kato, Naoko Iwata-Yoshikawa, Hideki Tani, Takeshi Kurosu, Hikaru Fujii, Natsumi Omura, Miho Shibamura, Shumpei Watanabe, Kazutaka Egawa, Takuya Inagaki, Satoko Sugimoto, Supranee Phanthanawiboon, Shizuko Harada, Souichi Yamada, Shuetsu Fukushi, Shigeru Morikawa, Noriyo Nagata, Masayuki Shimojima, Masayuki Saijo   +20 more
doaj   +1 more source

Droplet Digital CRISPR for Nucleic Acid Detection

Advanced Science, Volume 13, Issue 14, 9 March 2026.
This review outlines recent advances in droplet digital CRISPR technology for nucleic acid detection, combining CRISPR specificity with droplet digital‐based absolute quantification. It summarizes core principles, amplification‐assisted and amplification‐free strategies, and representative DNA and RNA biomarker applications.
Yang Zhang, Roy S. K. Walker, Anwar Sunna, Tracie J. Barber, Ming Li   +4 more
wiley   +1 more source

Integrated transcriptome profiling in THP-1 macrophages infected with bunyavirus SFTSV

Virus Research, 2021
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne bunyavirus that causes an emerging hemorrhagic fever termed SFTS with high mortality. However, knowledge of SFTSV-host interactions is largely limited. Here, we performed a global transcriptome analysis of mRNAs and lncRNAs in THP-1 macrophages infected with SFTSV for 24 and 48 h.
Jia-Min, Yan, Wen-Kang, Zhang, Fei, Li, Chuan-Min, Zhou, Xue-Jie, Yu   +4 more
openaire   +2 more sources