Results 31 to 40 of about 3,481 (207)

Rapid Spread of Severe Fever with Thrombocytopenia Syndrome Virus by Parthenogenetic Asian Longhorned Ticks [PDF]

, 2022
Publishe
Chandra, S, Cheng, C, Choi, YK, Chu, H, Fan, S, Gedye, K, Han, X, Jenkins, C, Jia, Y, Kanuka, H, Lawrence, K, Li, H, Liu, Q, Price, DC, Sun, J, Tanaka, T, Wang, Y, Yang, Z, Ye, L, Yu, T, Zhan, X, Zhang, G, Zhang, X, Zhang, Z, Zhao, C, Zheng, A   +25 more
core   +1 more source

Knockout of CLTC gene reduces but not completely block SFTSV infection

PLOS ONE, 2023
Clathrin is a key protein for viruses to enter host cells. Previous studies often use clathrin inhibitors or gene knockdown technology to partially inhibit the function of clathrin, but whether SFTSV can infect host cells without clathrin expression remains unclear.
Tiezhu Liu, Jiajia Li, Xueqi Wang, Tao Huang, Wei Wu, Aqian Li, Chuan Li, Xiaoxia Huang, Qin Wang, Dexin Li, Shiwen Wang, Mifang Liang   +11 more
openaire   +3 more sources

Severe fever with thrombocytopenia syndrome in children: a case report [PDF]

, 2014
BACKGROUND: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by a novel bunyavirus (SFTSV) in China. Humans of all ages living in endemic areas have high risk of acquiring SFTS.
Hong-Yu Wang, Li-Yuan Wang, Ning Cui, Qing-Bin Lu, Wei Liu, Wu-Chun Cao, Ying Wo   +6 more
core   +2 more sources

Integrated transcriptome profiling in THP-1 macrophages infected with bunyavirus SFTSV

Virus Research, 2021
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne bunyavirus that causes an emerging hemorrhagic fever termed SFTS with high mortality. However, knowledge of SFTSV-host interactions is largely limited. Here, we performed a global transcriptome analysis of mRNAs and lncRNAs in THP-1 macrophages infected with SFTSV for 24 and 48 h.
Jia-Min, Yan, Wen-Kang, Zhang, Fei, Li, Chuan-Min, Zhou, Xue-Jie, Yu   +4 more
openaire   +2 more sources

Ultra-rapid detection of nuclear protein of severe fever with thrombocytopenia syndrome virus by colloidal gold immunochromatography assay [PDF]

PeerJ
In 2009, severe fever with thrombocytopenia syndrome virus (SFTSV), also known as the Dabie bandavirus (DBV), was first discovered in Henan, China. It is a tick-borne zoonotic virus with a fatality rate ranging from 6% to 30%. Currently, we lack safe and
Zhiwei Huang, Jianhua Li, Wentao Wei, Hongyu Li, Hao Yan, Ruyi Chen, Jiaxuan Li, Xiaotian Tie, Di Wang, Guangshang Wu, Ling Zhang, Yanjun Zhang, Keda Chen, Yongliang Lou   +13 more
doaj   +2 more sources

Recent Advances in Humoral Immunity Dysregulation in Severe Fever With Thrombocytopenia Syndrome Virus (SFTSV) Infection: A Systematic Review. [PDF]

Health Sci Rep
ABSTRACT Background and Aims Severe fever with thrombocytopenia syndrome virus (SFTSV) infection causes profound dysregulation of humoral immunity, leading to immunopathology and impaired viral clearance. However, the mechanisms underlying B cell dysfunction and inadequate antibody responses remain poorly defined.
Hou H, Yuan X, Chen R, Xiong Z, Wu S, Wang F.   +5 more
europepmc   +2 more sources

Therapeutic efficacy of favipiravir against Bourbon virus in mice [PDF]

, 2019
Bourbon virus (BRBV) is an emerging tick-borne RNA virus in the orthomyxoviridae family that was discovered in 2014. Although fatal human cases of BRBV have been described, little is known about its pathogenesis, and no antiviral therapies or vaccines ...
Bailey, Thomas, Boon, Adrianus C. M., Bricker, Traci L, Diamond, Michael S, Gounder, Anshu P, Jagger, Brett W, Janowski, Andrew B, Kwon, Jennie H, Shafiuddin, Md., Wang, David, Williams, Graham D, Zhao, Guoyan   +11 more
core   +3 more sources

Emerging tick-borne infections in mainland China: an increasing public health threat [PDF]

, 2015
Since the beginning of the 1980s, 33 emerging tick-borne agents have been identified in mainland China, including eight species of spotted fever group rickettsiae, seven species in the family Anaplasmataceae, six genospecies in the complex Borrelia ...
Cao, Wu-Chun, Chen, Wan-Jun, Fang, Li-Qun, Gray, Gregory C., Jiang, Jia-Fu, Krause, Peter J., Li, Hao, Li, Xin-Lou, Liang, Song, Liu, Kun, Liu, Wei, Ma, Mai-Juan, Sun, Ruo-Xi, Sun, Ye, Yang, X. Frank, Yang, Yang, Yao, Hong-Wu, Zuo, Shu-Qing   +17 more
core   +1 more source

Differential Antagonism of Human Innate Immune Responses by Tick-Borne Phlebovirus Nonstructural Proteins [PDF]

, 2017
published_or_final_versio
Benjamin Brennan, Dong-Yan Jin, John Schoggins, Ping Li, Richard M. Elliott, Veronica V. Rezelj, Vidyanath Chaudhary   +6 more
core   +3 more sources

Interferon-stimulated gene (ISG)-expression screening reveals the specific antibunyaviral activity of ISG20 [PDF]

, 2018
Bunyaviruses pose a significant threat to human health, prosperity and food security. In response to viral infections, interferons (IFNs) upregulate the expression of hundreds of interferon stimulated genes (ISGs) whose cumulative action can potently ...
Bieniasz, Paul D., Brennan, Benjamin, Elliott, Richard M., Feng, Junjie, Koudriakova, Elina, Kreher, Felix, Rezelj, Veronica V., Rice, Charles M., Rihn, Suzannah J., Shaw, Andrew E., Shi, Xiaohong, Slack, Gillian S., Tilston-Lunel, Natasha L., Turnbull, Matthew L., Wickenhagen, Arthur, Wilson, Sam J.   +15 more
core   +1 more source