Results 31 to 40 of about 2,383 (169)

Integration of SFTSV Viral Load, Age, and Double-Negative B-Cells as Prognostic Biomarkers for Severe Fever With Thrombocytopenia Syndrome Outcomes. [PDF]

J Immunol Res
Background Severe fever with thrombocytopenia syndrome (SFTS) is a tick‐borne viral illness with high mortality, yet early risk stratification remains challenging. Recent evidence suggests that B‐cell dysregulation contributes to disease severity. Methods A cohort of 168 patients with confirmed SFTS was retrospectively analyzed. Flow cytometry was used
Wei W, Tai Q, Liu H, Chen R, Wang Y, Wang T, Ouyang R, Wu S, Wang F, Hou H.   +9 more
europepmc   +2 more sources

Viral shedding pattern of severe fever with thrombocytopenia syndrome virus in severely ill patients: A prospective, Multicenter cohort study

Heliyon
Background: Severe fever with thrombocytopenia syndrome (SFTS) is spreading rapidly in Asia. The pathway of SFTS virus shedding from patient and specific use of personal protective equipments (PPEs) against viral transmission have rarely been reported ...
Li-Fen Hu, Ting-Ting Bian, Qiang Chen, Meng-Yu Liu, Jia-Jia Li, Qin-Xiang Kong, Jian-Kang Zhang, Jin Wu, Jun Cheng, Rui Yu, Yan-Qin Qiu, Yu-Feng Gao, Guo-Sheng Chen, Ying Ye, Ting Wu, Jia-Bin Li   +15 more
doaj   +1 more source

SFTSV Prevalence in Ticks and Livestock in an SFTSV-Endemic Area in Central China

Pathogens
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne bunyavirus that causes a severe viral hemorrhagic fever (SFTS), with a very high case mortality rate, expanding epidemic areas, and increasing incidence. Due to the lack of an effective drug or vaccine for SFTS, reducing the incidence and mortality of SFTS primarily ...
Hui-Ya Lu, Guan-Du Wu, Meng Peng, Li-Bang Wu, Yi-Ming Luo, Bin Xia, Dan Xiong, Xiang-Rong Qin, Fang Guo, Xue-Jie Yu   +9 more
openaire   +2 more sources

High Seroprevalence of Severe Fever with Thrombocytopenia Syndrome Virus Infection among the Dog Population in Thailand

Viruses, 2023
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne zoonotic disease caused by the SFTS virus (SFTSV). In Thailand, three human cases of SFTS were reported in 2019 and 2020, but there was no report of SFTSV infection in animals ...
Keita Ishijima, Thanmaporn Phichitraslip, Nattakarn Naimon, Preeyaporn Ploypichai, Benyapa Kriebkajon, Torntun Chinarak, Jirasin Sridaphan, Anamika Kritiyakan, Noppadol Prasertsincharoen, Sathaporn Jittapalapong, Kanate Tangcham, Worawut Rerkamnuaychoke, Yudai Kuroda, Masakatsu Taira, Kango Tatemoto, Eunsil Park, Milagros Virhuez-Mendoza, Yusuke Inoue, Michiko Harada, Tsukasa Yamamoto, Ayano Nishino, Aya Matsuu, Ken Maeda   +22 more
doaj   +1 more source

Challenges of Dengue in Hematological Disease Patients: Descriptive Analysis From the DANGO Registry During the 2023–2024 Outbreak in Argentina

Transplant Infectious Disease, EarlyView.
During the 2023–2024 Argentine dengue outbreak, 33 patients with hematological disease showed high complication rates, frequent hospitalization (64%), severe thrombocytopenia (90%), and 6% dengue‐attributable mortality. Transfusion‐associated cases were documented.
Gustavo Adolfo Méndez, Carla Niveyro, Pedro Andrés Villalba Apestegui, Victoria Isabel Martin, Lucila María Compañy Kec, María Cynthia Tomasino, Mariana del Carmen del Marull, Haydee Ingrid Bernard, Claudia Patricia Lorena Fernández, Flavia Marcela Pelech, Maria Fernanda Tosin, María Fernanda González‐Hobecker, Karen Beatrice Duranona, Angela Daiana Jara, Justus Cornely, Oliver A. Cornely, Jon Salmanton‐García   +16 more
wiley   +1 more source

Coinfection of SFTSV Genotype A with Rickettsia among Farmers in Northeast [PDF]

, 2020
Severe fever with thrombocytopenia syndrome (SFTS), caused by the SFTS virus (SFTSV), is a new acute infectious disease transmitted by ticks. Rickettsiosis is caused by Rickettsia spp. carried by ticks. Here, we conducted case analyses and molecular biological diagnosis of some patients with suspected SFTS in Liaoning Province in 2019 to identify rates
Yue Ma, Hongyan Liu, Jixu Li, Dan Li, Yan Wang, Fenghua Jiang, Qingtian Gao, Xiaohu Han, Guoshun Shen, Zeliang Chen   +9 more
openaire   +1 more source

Lysine l‐Lactylation: Bridging Metabolism, Chromatin and Disease

Cell Proliferation, Volume 59, Issue 8, August 2026.
Enzymatic regulation of KL‐la. The enzymatic regulation of KL‐la involves two distinct pathways for L‐lactate accumulation: intracellular production through glycolysis‐derived pyruvate conversion by lactate dehydrogenase (LDH) or direct cellular uptake via monocarboxylate transporters (MCTs). These L‐lactate pools fuel two distinct lactylation pathways—
Anoosha Malik, Muhammad Dilawar, Junguang Liao, Jie Zheng, Qitao Qian, Ming Xu, Sisi Lin, Xiaobo Zhu, Qiuwei Ge, Limin Jin, Guiqian Chen   +10 more
wiley   +1 more source

An Explainable Machine Learning Model for Early Prediction of Incident Myocardial Injury in Patients With Severe Fever With Thrombocytopenia Syndrome

Journal of Medical Virology, Volume 98, Issue 7, July 2026.
ABSTRACT This study aimed to develop an explainable machine learning–based model to enable early prediction of incident myocardial injury during hospitalization among patients with severe fever with thrombocytopenia syndrome (SFTS). This multicenter retrospective cohort study included and analyzed clinical data from 1,088 patients with SFTS who were ...
Xiang Li, Xiaotong Yu, Wei Zhou, Sujuan Zhang, Zibo Fan, Yuanni Liu, Yi Shen, Zhenghua Zhao, Jianping Duan, Ling Lin, Zhihai Chen, Wei Zhang   +11 more
wiley   +1 more source

Molecular detection of Rickettsia, Hepatozoon, Ehrlichia and SFTSV in goat ticks

Veterinary Parasitology: Regional Studies and Reports, 2020
Ticks are vectors of various pathogens to people, livestock, companion animals and wildlife. We describe here the ticks found on goats in Anhui province of China and the results of molecular studies on six tick-borne pathogens they might harbor. Among 125 ticks collected (119 Haemaphysalis longicornis, n = 119; Rhipicephalus microplus, n = 6), we ...
Jing, Li, Patrick, Kelly, Weina, Guo, Jilei, Zhang, Yi, Yang, Weiguo, Liu, Chengming, Wang   +6 more
openaire   +3 more sources

Severe fever with thrombocytopenia syndrome virus infection during pregnancy in C57/BL6 mice causes fetal damage.

PLoS Neglected Tropical Diseases, 2020
BackgroundSevere fever with thrombocytopenia syndrome virus (SFTSV) is a novel tick-borne phlebovirus, which is listed in the most dangerous pathogens by the World Health Organization, and has 12-30% fatality rates.
Rui Chen, Zeng-Qiang Kou, Xiao-Rui Wang, Shu-Han Li, Hai-Lu Zhang, Zi-Wei Liu, Dong Cheng, Zhi-Yu Wang, Xue-Jie Yu, Hong-Ling Wen   +9 more
doaj   +1 more source