Results 21 to 30 of about 3,481 (207)

Epidemiologic Features and Environmental Risk Factors of Severe Fever with Thrombocytopenia Syndrome, Xinyang, China [PDF]

, 2014
Background:Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease discovered in rural areas of Central China in 2009, caused by a novel bunyavirus ...
Cao, W.-C. (Wu-Chun), Cui, N. (Ning), Fang, L.Q. (Lily), Gray, G.C. (Gregory), Li, H. (Hao), Liang, S. (Song), Liu, K. (Kun), Liu, W. (Wei), Lu, Q.-B. (Qing-Bin), Peng, W. (Wei), Vlas, S.J. (Sake) de, Wang, B.-J. (Bing-Jun), Wang, H.-Y. (Hong-Yu), Wang, L.-Y. (Li-Yuan), Yang, H. (Hong), Zhang, Y.-Y. (Yao-Yun), Zhuang, L. (Lu)   +16 more
core   +9 more sources

Genetic Susceptibility Is One of the Determinants for Severe Fever with Thrombocytopenia Syndrome Virus Infection and Fatal Outcome: An Epidemiological Investigation. [PDF]

PLoS ONE, 2015
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease in China and case-fatality rate of SFTS is very high (approximately 10%).
Jimin Sun, Yuming Tang, Feng Ling, Yue Chang, Xiaohong Ye, Wen Shi, Lei Zhang, Zhiping Chen, Haijiang Lin, Zaiping Qiu, Yanjun Zhang, Rong Zhang, Haiyan Mao, Enfu Chen, Junfen Lin, Jianmin Jiang, Shichang Xia, Zhenyu Gong   +17 more
doaj   +1 more source

Severe fever with thrombocytopenia syndrome virus trends and hotspots in clinical research: A bibliometric analysis of global research

Frontiers in Public Health, 2023
BackgroundSince severe fever with thrombocytopenia syndrome virus (SFTSV) was first reported in 2009, a large number of relevant studies have been published. However, no bibliometrics analysis has been conducted on the literature focusing on SFTSV.
Zhengyu Zhang, Juntao Tan, Wen Jin, Hong Qian, Loulei Wang, Hu Zhou, Yuan Yuan, Xiaoxin Wu   +7 more
doaj   +1 more source

Ecology of the Tick-Borne Phlebovirus Causing Severe Fever with Thrombocytopenia Syndrome in an Endemic Area of China. [PDF]

PLoS Neglected Tropical Diseases, 2016
BACKGROUND:Severe fever with thrombocytopenia syndrome (SFTS) is caused by SFTS virus (SFTSV), a tick-borne phlebovirus in family Bunyaviridae. Studies have found that humans, domestic and wildlife animals can be infected by SFTSV.
Zhifeng Li, Changjun Bao, Jianli Hu, Wendong Liu, Xiaochen Wang, Lei Zhang, Zhengmin Ji, Zhi Feng, Luxun Li, Aihua Shen, Xuejian Liu, Hongjun Zhao, Wenwen Tan, Jiangang Zhou, Xian Qi, Yefei Zhu, Fenyang Tang, Carol J Cardona, Zheng Xing   +18 more
doaj   +1 more source

M Segment-Based Minigenome System of Severe Fever with Thrombocytopenia Syndrome Virus as a Tool for Antiviral Drug Screening

Viruses, 2021
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne bunyavirus that causes severe disease in humans with case fatality rates of approximately 30%. There are few treatment options for SFTSV infection. SFTSV RNA synthesis is
Hiroshi Yamada, Satoshi Taniguchi, Masayuki Shimojima, Long Tan, Miyuki Kimura, Yoshitomo Morinaga, Takasuke Fukuhara, Yoshiharu Matsuura, Takashi Komeno, Yousuke Furuta, Masayuki Saijo, Hideki Tani   +11 more
doaj   +1 more source

Severe fever with thrombocytopenia syndrome virus induces platelet activation and apoptosis via a reactive oxygen species-dependent pathway

Redox Biology, 2023
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne infectious disease caused by the SFTS virus (SFTSV) and with a high fatality rate.
Yi-Hui Li, Xue-Hui Wang, Wen-Wu Huang, Ren-Rong Tian, Wei Pang, Yong-Tang Zheng   +5 more
doaj   +1 more source

Mapping of transcription termination within the S segment of SFTS phlebovirus facilitated the generation of NSs-deletant viruses [PDF]

, 2017
SFTS phlebovirus (severe fever with thrombocytopenia syndrome virus; SFTSV) is an emerging tick-borne bunyavirus that was first reported in China in 2009. Here we report the generation of a recombinant SFTSV (rHB29NSsKO) that cannot express the viral non-
Brennan, Benjamin, Elliott, Richard M., Rezelj, Veronica V.   +2 more
core   +1 more source

Infection of humanized mice with a novel phlebovirus presented pathogenic features of severe fever with thrombocytopenia syndrome.

PLoS Pathogens, 2021
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne emerging phlebovirus with high mortality rates of 6.0 to 30%. SFTSV infection is characterized by high fever, thrombocytopenia, leukopenia, hemorrhage and multiple organ failures ...
Shijie Xu, Na Jiang, Waqas Nawaz, Bingxin Liu, Fang Zhang, Ye Liu, Xilin Wu, Zhiwei Wu   +7 more
doaj   +1 more source

Construction and Characterization of Severe Fever with Thrombocytopenia Syndrome Virus with a Fluorescent Reporter for Antiviral Drug Screening

Viruses, 2023
Severe fever with thrombocytopenia syndrome (SFTS) caused by a novel bunyavirus (SFTSV) is an emerging infectious disease with up to 30% case fatality. Currently, there are no specific antiviral drugs or vaccines for SFTS. Here, we constructed a reporter
Xiao Wang, Mingyue Xu, Huanhuan Ke, Longda Ma, Liushuai Li, Jiang Li, Fei Deng, Manli Wang, Zhihong Hu, Jia Liu   +9 more
doaj   +1 more source

Suppression of type I and type III interferon signalling by NSs protein of severe fever-with-thrombocytopenia syndrome virus through inhibition of STAT1 phosphorylation and activation [PDF]

, 2015
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne pathogen causing significant morbidity and mortality in Asia. NSs protein of SFTSV is known to perturb type I IFN induction and signalling, but the mechanism remains to ...
Chan, CP, Chaudhary, V, Fung, SY, Jin, D, Kok, KH, Li, C, Li, D, Liang, M, Lui, PY, Wang, PH, Yuen, KS, Zhang, S   +11 more
core   +1 more source