Results 21 to 30 of about 3,280 (212)

Lethal Disease in Dogs Naturally Infected with Severe Fever with Thrombocytopenia Syndrome Virus

Viruses, 2022
Severe fever with the thrombocytopenia syndrome virus (SFTSV) causes fatal disease in humans, cats, and cheetahs. In this study, the information on seven dogs with SFTS was summarized.
Keita Ishijima, Kango Tatemoto, Eunsil Park, Masanobu Kimura, Osamu Fujita, Masakatsu Taira, Yudai Kuroda, Milagros Virhuez Mendoza, Yusuke Inoue, Michiko Harada, Aya Matsuu, Hiroshi Shimoda, Ryusei Kuwata, Shigeru Morikawa, Ken Maeda   +14 more
doaj   +1 more source

Severe Fever with Thrombocytopenia Syndrome in Cats and Its Prevalence among Veterinarian Staff Members in Nagasaki, Japan

Viruses, 2021
In this study, we investigated severe fever with thrombocytopenia syndrome (SFTS) virus (SFTSV) infection in cats in Nagasaki, Japan. In total, 44 of 133 (33.1%) cats with suspected SFTS were confirmed to be infected with SFTSV.
Tsuyoshi Ando, Takeshi Nabeshima, Shingo Inoue, Mya Myat Ngwe Tun, Miho Obata, Weiyin Hu, Hiroshi Shimoda, Shintaro Kurihara, Koichi Izumikawa, Kouichi Morita, Daisuke Hayasaka   +10 more
doaj   +1 more source

SAFA initiates innate immunity against cytoplasmic RNA virus SFTSV infection

PLoS Pathogens, 2021
Nuclear scaffold attachment factor A (SAFA) is a novel RNA sensor involved in sensing viral RNA in the nucleus and mediating antiviral immunity. Severe fever with thrombocytopenia syndrome virus (SFTSV) is a bunyavirus that causes SFTS with a high ...
Bin-yan Liu, Xue-jie Yu, Chuan-min Zhou
doaj   +2 more sources

Oral and ocular transmission of severe fever with thrombocytopenia syndrome virus

Infectious Medicine, 2022
Background: Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tick-borne bunyavirus that could cause a severe hemorrhagic fever termed SFTS with a high fatality rate of up to 30%.
Chuan-Min Zhou, Rui Qi, Xiang-Rong Qin, Li-Zhu Fang, Hui-Ju Han, Xiao-Ying Lei, Xue-Jie Yu   +6 more
doaj   +1 more source

M Segment-Based Minigenome System of Severe Fever with Thrombocytopenia Syndrome Virus as a Tool for Antiviral Drug Screening

Viruses, 2021
Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick-borne bunyavirus that causes severe disease in humans with case fatality rates of approximately 30%. There are few treatment options for SFTSV infection. SFTSV RNA synthesis is
Hiroshi Yamada, Satoshi Taniguchi, Masayuki Shimojima, Long Tan, Miyuki Kimura, Yoshitomo Morinaga, Takasuke Fukuhara, Yoshiharu Matsuura, Takashi Komeno, Yousuke Furuta, Masayuki Saijo, Hideki Tani   +11 more
doaj   +1 more source

Genetic Susceptibility Is One of the Determinants for Severe Fever with Thrombocytopenia Syndrome Virus Infection and Fatal Outcome: An Epidemiological Investigation. [PDF]

PLoS ONE, 2015
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease in China and case-fatality rate of SFTS is very high (approximately 10%).
Jimin Sun, Yuming Tang, Feng Ling, Yue Chang, Xiaohong Ye, Wen Shi, Lei Zhang, Zhiping Chen, Haijiang Lin, Zaiping Qiu, Yanjun Zhang, Rong Zhang, Haiyan Mao, Enfu Chen, Junfen Lin, Jianmin Jiang, Shichang Xia, Zhenyu Gong   +17 more
doaj   +1 more source

Immunization with Recombinant SFTSV/NSs Protein Does Not Promote Virus Clearance in SFTSV-Infected C57BL/6J Mice [PDF]

Viral Immunology, 2015
The severe fever with thrombocytopenia syndrome (SFTS), caused by a novel Phlebovirus in the Bunyaviridae family named SFTS virus (SFTSV), is an emerging hemorrhagic fever with a wide distribution and high case-fatality rate. Neither effective treatment nor vaccines are available to treat and prevent this disease to date.
Rong, Liu, Dou-Dou, Huang, Jie-Ying, Bai, Lu, Zhuang, Qing-Bin, Lu, Xiao-Ai, Zhang, Wei, Liu, Jing-Yu, Wang, Wu-Chun, Cao   +8 more
openaire   +2 more sources

Detection of SFTSV genotypes by SFTSV DETECTR.

, 2022
The in vitro-transcribed RNA fragments of S gene from SFTSV genotypes A, B, C, D, E and F were amplified via RT-RPA with a primer set specific for the SFTSV S gene.
Misun Kim (3089739), Yoon-Jae Song (490039), Sang Taek Heo (12023162), Jeong Rae Yoo (12023171), Bum Ju Park (13189846), Keun Hwa Lee (8605227)   +5 more
core   +1 more source

SAFA deficiency promotes SFTSV replication.

, 2021
(A-B) THP-1 cells were transfected with SAFA siRNA (10 μM, 24 h) and control siRNA (10 μM, 24 h), and infected with SFTSV (MOI = 10) for 48 h, mRNA (A) and protein (B) levels of SFTSV NP were analyzed by RT-PCR and Western blot.
Xue-jie Yu (523802), Chuan-min Zhou (8861861), Bin-yan Liu (11719054)   +2 more
core   +1 more source

Ecology of the Tick-Borne Phlebovirus Causing Severe Fever with Thrombocytopenia Syndrome in an Endemic Area of China. [PDF]

PLoS Neglected Tropical Diseases, 2016
BACKGROUND:Severe fever with thrombocytopenia syndrome (SFTS) is caused by SFTS virus (SFTSV), a tick-borne phlebovirus in family Bunyaviridae. Studies have found that humans, domestic and wildlife animals can be infected by SFTSV.
Zhifeng Li, Changjun Bao, Jianli Hu, Wendong Liu, Xiaochen Wang, Lei Zhang, Zhengmin Ji, Zhi Feng, Luxun Li, Aihua Shen, Xuejian Liu, Hongjun Zhao, Wenwen Tan, Jiangang Zhou, Xian Qi, Yefei Zhu, Fenyang Tang, Carol J Cardona, Zheng Xing   +18 more
doaj   +1 more source