Results 41 to 50 of about 9,424 (215)

SGLT1 overexpression in cervical tumors.

, 2013
A) MAP17 expression in Hela cells increases glucose uptake that is blocked by the SGLT inhibitor phloridzine. B) Western blot analysis was performed for SGLT1 in Hela cells expressing MAP17 or vector alone (V). C) Representative images are shown of SGLT1
Juan M. Praena-Fernandez (281761), Guiovanna Roncador (281766), Angel Garcia (90471), Juan J. Marin (281767), Marco Perez (281760), Maria A. Lopez-Garcia (281763), Matilde Lleonart (281765), Blanca Felipe-Abrio (281762), Amancio Carnero (43507), Antonio Lucena-Cacace (281764)   +9 more
core   +1 more source

Na+-d-glucose Cotransporter SGLT1 is Pivotal for Intestinal Glucose Absorption and Glucose-Dependent Incretin Secretion [PDF]

, 2011
To clarify the physiological role of Na+-d-glucose cotransporter SGLT1 in small intestine and kidney, Sglt1−/− mice were generated and characterized phenotypically. After gavage of d-glucose, small intestinal glucose
Gorboulev, Valentin, Rexhepaj, Rexhep, Sendtner, Michael, Aruna Srinivasan, Wiese, Stefan, Reimann, Frank, Maike Veyhl-Wichmann, Cunard, Robyn, Breljak, Davorka, Alexander Jaschke, Schürmann, Annette, Klessen, Dirk, Gribble, Fiona M, Robyn Cunard, Balen, Daniela, Helmut Kipp, Alexandra Friedrich, Daniela Balen, Helen E. Parker, Hermann Koepsell, Rexhep Rexhepaj, Frank Reimann, Fiona M. Gribble, Friedrich, Alexandra, Valentin Gorboulev, Timo Rieg, Jaschke, Alexander, Annette Schürmann, Kipp, Helmut, Lang, Florian, Stephan Scherneck, Srinivasan, Aruna, Davorka Breljak, Scherneck, Stephan, Rieg, Timo, Parker, Helen E, Sabolic, Ivan, Volker Vallon, Florian Lang, Koepsell, Hermann, Stefan Wiese, Veyhl-Wichmann, Maike, Ivan Sabolic, Michael Sendtner, Vallon, Volker, Dirk Klessen   +45 more
core   +2 more sources

Short Communication: Immunohistochemical study of sodium-dependent glucose co-transporters in ostriches kidneys

Agraarteadus, 2020
Out of the two families of glucose transporters identified, the sodium-dependent glucose co-transporters contribute to renal glucose reabsorption. Due to the lack of knowledges of the localization of SGLTs in bird's kidneys, the present study aimed to ...
Piret Hussar, Ilmārs Dūrītis, Florina Popovska-Percinic, Tõnu Järveots   +3 more
doaj   +1 more source

The regulation of SGLT1.

, 2013
SGLT1 expression is not significantly altered with 30 mM high glucose and SGLT2 inhibition after 72 hours (A). GLUT2 expression is not altered with 30 mM high glucose and SGLT2 inhibition (B). HK2 cells were incubated with 5 mM (ctrl), 30 mM high glucose,
Simon Gross (285318), Carol Pollock (279260), Kate Pegg (285316), Amanda Mather (285324), Harshini Mudaliar (285321), Usha Panchapakesan (285314), Josephine Forbes (285322), Muralikrishna Gangadharan Komala (285320)   +7 more
core   +1 more source

Default parameters of the SGLT1 model.

, 2015
Default parameters of the SGLT1 model.
Morten Gram Pedersen (505334), Michela Riz (505333)   +1 more
core   +1 more source

Molecular characterization and nutritional regulation of sodium-dependent glucose cotransporter 1 (Sglt1) in blunt snout bream (Megalobrama amblycephala)

Scientific Reports, 2021
Fish has poor utilization capacity for glucose metabolism. The possible reasons are related to the core regulatory elements of glucose metabolism: transport proteins.
Hualiang Liang, Xianping Ge, Mingchun Ren, Lu Zhang, Dong Xia, Ji Ke, Liangkun Pan   +6 more
doaj   +1 more source

Integration of Nutrition and Organic Agriculture Framework in Managing Gastrointestinal Nematodes in Ruminants

Animal Research and One Health, EarlyView.
Gastrointestinal nematode infections damage the gastrointestinal epithelial tissues of ruminants, affecting nutrient utilization and overall production performance. This review outlines host‐gastrointestinal nematode interactions and discusses integrated control strategies, including nutritional supplementation, grazing management, vaccines, and ...
Wenxun Chen, Xiangfang Tang, Yimin Zhuang, Shengjun Zhao, Ying Ren, Xiaokang Lv   +5 more
wiley   +1 more source

Combined SGLT1 and SGLT2 Inhibitors and Their Role in Diabetes Care [PDF]

Diabetes Technology & Therapeutics, 2018
The sodium–glucose cotransporter type 1 (SGLT1) is the primary transporter for absorption of glucose and galactose in the gastrointestinal tract. Inhibition blunts and delays postprandial glucose (PPG) excursion. Sodium–glucose cotransporter type 2 (SGLT2) is expressed in the kidney, where it reabsorbs 90% of filtered glucose.
Thomas, Danne, Torben, Biester, Olga, Kordonouri   +2 more
openaire   +2 more sources

Use systems pharmacology modeling to elucidate the operating characteristics of SGLT1 and SGLT2 in renal glucose reabsorption in humans

Frontiers in Pharmacology, 2014
In the kidney, glucose in glomerular filtrate is reabsorbed primarily by sodium-glucose cotransporters 1 (SGLT1) and 2 (SGLT2) along the proximal tubules.
Yasong eLu, Steven C Griffen, David W Boulton, Tarek A Leil   +3 more
doaj   +1 more source

Sodium/glucose cotransporter 1-dependent metabolic alterations induce tamoxifen resistance in breast cancer by promoting macrophage M2 polarization

Cell Death and Disease, 2021
Endocrine therapy is the standard treatment for estrogen receptor (ER)-positive breast cancer, but tumors eventually develop resistance. However, endocrine therapy resistance mechanisms mediated through interactions between breast cancer cells and tumor ...
Xingjian Niu, Jianli Ma, Jingtong Li, Yucui Gu, Lei Yin, Yiran Wang, Xiaoping Zhou, Jinlu Wang, Hongfei Ji, Qingyuan Zhang   +9 more
doaj   +1 more source