Results 61 to 70 of about 9,424 (215)
Food Chemistry International, EarlyView.The study demonstrates how functional foods, medicinal plants, phytochemicals, bioactive compounds and essential nutrients combat metabolic diseases. It highlights their mechanisms, including antioxidant, anti‐inflammatory, insulin‐sensitising, lipid‐regulating, gut microbiota‐modulating and mitochondrial‐enhancing effects, leading to improved ...
Chinaza Godswill Awuchi +2 more
wiley +1 more source
Contribution of SGLT1 in cardiac glucose transport
Archives of Cardiovascular Diseases Supplements, 2019 Introduction Sodium-glucose transporter 1 (SGLT1) is the major SGLT isoform expressed in the heart. Under baseline condition, its absence does not affect heart function and structure. Using the pharmacological SGLT1 inhibitor, phlorizin, several data suggested that SGLT1 could contribute to overall glucose transport under physiological as well as ...
L. Ferté +9 more
openaire +1 more source
The correlation between MAP17 and SGLT1 expression levels in the same tumor samples.
, 2013 A) A graph is shown depicting MAP17-SGLT1 correlations in all samples analyzed. Statistical analyses were performed using a 1-way ANOVA. B) Three representative examples of a positive correlation are shown (P1, P2 and P3 are 3 different tumor samples ...
Juan M. Praena-Fernandez (281761) +9 more
core +1 more source
CellsIn the small intestine, sodium (Na) absorption occurs primarily via two apical transporters, Na-hydrogen exchanger 3 (NHE3) and Na-glucose cotransporter 1 (SGLT1).
Jennifer Haynes +3 more
doaj +1 more source
SGLT1/2 inhibition improves glycemic control and multi-organ protection in type 1 diabetes
iScience, 2023 Summary: Sodium glucose cotransporters (SGLTs) are transport proteins that are expressed throughout the body. Inhibition of SGLTs is a relatively novel therapeutic strategy to improve glycemic control and has been shown to promote cardiorenal benefits ...
Lakshini Yasaswi Herat +5 more
doaj +1 more source
iNew Medicine, EarlyView.ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang +9 more
wiley +1 more source
Journal of the Science of Food and Agriculture, EarlyView.Abstract Energy bars are widely consumed functional foods among athletes and physically active consumers who require convenient sources of sustained energy. Their carbohydrate composition, particularly the type and ratio of digestible sugars such as glucose, fructose and sucrose, strongly influences glycaemic index (GI), postprandial blood glucose ...
Raju Sasikumar +8 more
wiley +1 more source
Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic Risk
Journal of the American College of Cardiology, 2018 Background: Loss-of-function mutations in the SGLT1 (sodium/glucose co-transporter-1) gene result in a rare glucose/galactose malabsorption disorder and neonatal death if untreated. In the general population, variants related to intestinal glucose absorption remain uncharacterized.
Seidelmann, S. B. (Sara B.) +16 more
openaire +4 more sources
Pharmacology Research & Perspectives, 2021 Previously, we showed that sodium/glucose cotransporter 1 (SGLT1) participates in vascular cognitive impairment in small vessel disease. We hypothesized that SGLT1 inhibitors can improve the small vessel disease induced‐vascular cognitive impairment.
Nanae Ishida +6 more
doaj +1 more source
Phytotherapy Research, EarlyView.Schematic overview of the multi‐target and multi‐pathway mechanisms of PDBI in the prevention and management of hypertension. ABSTRACT Hypertension remains a major global risk factor for cardiovascular diseases, yet current treatments face challenges such as suboptimal blood pressure control and inadequate organ protection.
Qiqi Deng +6 more
wiley +1 more source