Results 161 to 170 of about 38,769 (305)

Docking-Based Classification of SGLT2 Inhibitors

Inhibitors of the Sodium/Glucose co-transporter 2 (SGLT2) have been evolving into an important contribution to the treatment of diabetes mellitus.
Ajouan Mazoudji, Gerhard F. Ecker
core   +1 more source

Impact of Time of Injection on the Efficacy and Safety of iGlarLixi Versus IDegAsp in Chinese People With Type 2 Diabetes: Exploratory Analysis of the Soli‐D Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To compare the efficacy and safety of the fixed‐ratio combination of insulin glargine 100 U/mL plus lixisenatide (iGlarLixi) with premixed insulin degludec plus insulin aspart (IDegAsp) according to the injection time of IDegAsp. Materials and Methods The 24‐week, multicentre, randomised, open‐label Soli‐D study enrolled Chinese adults ...
Xin Li, Juan Wang, Tong Liu, Agustina Alvarez, Felipe Lauand, Lydie Melas‐Melt, Lei Kang, Qin Du, Ming Liu   +8 more
wiley   +1 more source

SGLT2 Inhibitors in Alzheimer's Disease: Biochemical Insights and Therapeutic Potential. [PDF]

Int J Mol Sci
Mazzeo P, Vietri M, Tecce N, Delizia A, Remondelli V, Ciaglia T, Di Dio A, Corletti L, Pizzuti CG, Pepe G, Stabile E, Correale M, Campiglia P, Miranda MR, Tecce MF, Vestuto V.   +15 more
europepmc   +1 more source

Optimización SGLT2 para cardionefro protección

Sodium-glucose co-transporter 2 (sglt2) inhibitors not only regulate glucose levels in type 2 diabetes but also offer renal and cardiovascular protection.
Yukiko Harumi Yamasaki Ramos, Marbella Haddad Toledo, Haddad Toledo, Marbella, Yamasaki Ramos, Yukiko Harumi   +3 more
core   +1 more source

Chronic Kidney Disease in Patients With Type 2 Diabetes Mellitus: A Cross‐Sectional Population‐Based Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Chronic kidney disease (CKD) is a common complication of Type 2 diabetes that frequently co‐occurs with cardiovascular disease. We aimed to characterise CKD in adults with Type 2 diabetes, quantify its prevalence across severity levels and examine pharmacological treatment patterns and healthcare utilisation.
Neora Alterman, Yoel Toledano, Noga Fallach, Victor Gross, Galia Zacay   +4 more
wiley   +1 more source

SGLT2 Inhibitors in Cardio-Oncology: A Systematic Review and Meta-Analysis. [PDF]

JACC Adv
Spadafora L, Bernardi M, Sarto G, Simeone B, Rocco E, Carbone S, Dalla Vecchia LA, Pedretti RFE, Valenti V, Di Mario R, Forte M, Frati G, Abbate A, Golino M, Versaci F, Peruzzi M, Sabouret P, Biondi Zoccai G, Sciarretta S.   +18 more
europepmc   +1 more source

Diabetes and menopause: A critical yet neglected intersection

Diabetic Medicine, EarlyView.
Isabell Haage, David Studer, Petra Stute, Lia Bally   +3 more
wiley   +1 more source

The Effects of Combined Antihypertensive and Antidiabetic Therapies on Cardiovascular Outcomes: A Systematic Review and Meta‐Analysis

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Hypertension and diabetes frequently coexist, yet the net clinical impact of intentionally combining antihypertensive (AHTN) and antidiabetic (ADA) therapies on cardiovascular (CV) outcomes is uncertain. Here we quantified the effects of AHTN and ADA co‐therapy on CV and blood pressure (BP)/heart rate (HR) outcomes.
Wan Chin Hsieh, Brandon Michael Henry, István Édes   +2 more
wiley   +1 more source

Evidence on SGLT2 Inhibitors' Efficacy in Older and Frail Patients. [PDF]

J Clin Med
Kochanowska A, Mamcarz A, Wełnicki M.
europepmc   +1 more source

Impact of Sleeve Gastrectomy Versus Intensive Lifestyle Modifications With Obesity Management Medications on BMI Trajectory and Target Attainment: A Prospective Matched Cohort Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To compare sleeve gastrectomy (SG) with intensive lifestyle modification combined with obesity management medications (ILM/OMMs) in adults with severe obesity, focusing on BMI trajectory, time to achieving clinically meaningful weight loss, and metabolic outcomes in a real‐world clinical setting.
Maria Francesca Russo, Giovanni Casella, Giulia Angelini, Sara Russo, James Casella‐Mariolo, Vito D'Andrea, Giulio Illuminati, Lidia Castagneto‐Gissey   +7 more
wiley   +1 more source