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Nihon rinsho. Japanese journal of clinical medicine, 2016
SGLT2 is a glucose transporter which plays an important role for reabsorption of urinary glucose depending on the sodium concentration gradient. SGLT2 is mainly present in apical site of S1 segment of renal proximal tubule and accounts for approximately 90% of total urinary glucose reabsorption. SLC5a2, which codes SGLT2, is also known as the causative
Naoto, Kubota, Takashi, Kadowaki
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SGLT2 is a glucose transporter which plays an important role for reabsorption of urinary glucose depending on the sodium concentration gradient. SGLT2 is mainly present in apical site of S1 segment of renal proximal tubule and accounts for approximately 90% of total urinary glucose reabsorption. SLC5a2, which codes SGLT2, is also known as the causative
Naoto, Kubota, Takashi, Kadowaki
openaire +1 more source
SGLT2 inhibitors: are they safe?
Postgraduate Medicine, 2017Sodium-glucose linked transporter type 2 (SGLT2) inhibitors are a relatively new class of antidiabetic drugs with positive cardiovascular and kidney effects. The aim of this review is to present the safety issues associated with SGLT2 inhibitors. Urogenital infections are the most frequently encountered adverse events, although tend to be mild to ...
Sebastian Filippas-Ntekouan +2 more
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An update on the safety of SGLT2 inhibitors
Expert Opinion on Drug Safety, 2019Sodium-glucose cotransporter type 2 inhibitors (SGLT2is) are recommended after metformin for a large spectrum of patients with type 2 diabetes, because of a favorable benefit/risk profile despite a variety of adverse events.This narrative review discusses the safety profile of SGLT2is: initial concerns (cardiovascular safety, acute renal failure ...
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Impact of SGLT2 Inhibitors on Heart Failure: From Pathophysiology to Clinical Effects
International Journal of Molecular Sciences, 2021Alfredo Caturano +2 more
exaly
Emergence of SGLT2 Inhibitors as Powerful Antioxidants in Human Diseases
Antioxidants, 2021Wen-Chin Lee, , Kai-Fan Tsai
exaly