Results 91 to 100 of about 4,979,837 (328)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Shadow Honeypots [PDF]

open access: yes, 2010
We present Shadow Honeypots, a novel hybrid architecture that combines the best features of honeypots and anomaly detection. At a high level, we use a variety of anomaly detectors to monitor all traffic to a protected network or service.
Akritidis, Periklis   +5 more
core   +2 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

IMPROVED MOTION SEGMENTATION BASED ON SHADOW DETECTION [PDF]

open access: yesELCVIA Electronic Letters on Computer Vision and Image Analysis, 2007
In this paper, we discuss common colour models for background subtraction and problems related to their utilisation are discussed. A novel approach to represent chrominance information more suitable for robust background modelling and shadow suppression is proposed. Our method relies on the ability to represent colours in terms of a 3D-polar coordinate
Kampel, Martin   +3 more
openaire   +5 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Near real-time flood detection in urban and rural areas using high resolution Synthetic Aperture Radar images [PDF]

open access: yes, 2012
A near real-time flood detection algorithm giving a synoptic overview of the extent of flooding in both urban and rural areas, and capable of working during night-time and day-time even if cloud was present, could be a useful tool for operational flood ...
Bates, Paul   +4 more
core   +1 more source

Moving Cast Shadow Detection

open access: yes, 2007
In this chapter, we have provided a brief overview of the works about moving cast shadow detection. The state-of-the-art methods have been categories into color model, textural model, and geometric model according to the information and model utilized, which have been disscussed systemically.
Zhang, Wei   +2 more
openaire   +3 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Object-based change detection method for high-resolution remote sensing image combining shadow compensation and multi-scale fusion

open access: yesTongxin xuebao, 2018
As an interpreting symbol of remote sensing images,shadow,however,brings about “pseudo changes”,which is one of the main sources leading to error detection in high-resolution remote sensing image change detection.For this issue,an object-based high ...
Chao WANG   +4 more
doaj   +2 more sources

ORGB: Offset Correction in RGB Color Space for Illumination-Robust Image Processing

open access: yes, 2017
Single materials have colors which form straight lines in RGB space. However, in severe shadow cases, those lines do not intersect the origin, which is inconsistent with the description of most literature.
Li, Ge   +3 more
core   +1 more source

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