Results 81 to 90 of about 29,954 (261)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Automatic detection and removal of static shadows

Journal of Measurement Science and Instrumentation, 2020
In case of complex textures, existing static shadow detection and removal algorithms are prone to false detection of the pixels. To solve this problem, a static shadow detection and removal algorithm based on support vector machine（SVM） and region sub ...
HOU Tao, WU Hai-ping
doaj  

Shadow detection and removal from images using machine learning and morphological operations

The Journal of Engineering, 2019
In this study, the authors present a system for shadow detection and removal from images using machine learning technique. A machine learning algorithm ESRT (enhanced streaming random tree) model is proposed.
Vicky Nair, Parimala Geetha Kosal Ram, Sundaravadivelu Sundararaman   +2 more
doaj   +1 more source

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Target Detection Based on Spectral Derivation in HSI Shadow Region Classified by Convolutional Neural Networks

Canadian Journal of Remote Sensing, 2019
Because of the low reflection value of the shadow regions in hyperspectral image (HSI), these regions were deleted directly or ignored in target detection or classification.
Xuefeng Liu, Congcong Wang, Yue Meng, Hao Wang, Min Fu, Salah Bourennane   +5 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

A review of research on remote sensing images shadow detection and application to building extraction

European Journal of Remote Sensing
Buildings are one of the most important habitats for humans, and therefore, accurate identification and extraction of building information in remote sensing images are crucial. Buildings in remote sensing images vary in shape and color due to differences
Xueyan Dong, Jiannong Cao, Weiheng Zhao
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

A Review on Various Shadow Detection and Compensation Techniques in Remote Sensing Images

Canadian Journal of Remote Sensing, 2017
Remote sensing images provide a valuable source of information about the earth's surface. The presence of shadow can reduce the amount of information that can be extracted from these images.
Yasser Mostafa
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source