Results 101 to 110 of about 4,979,837 (328)
Observation of the Shadowing of Cosmic Rays by the Moon using a Deep Underground Detector [PDF]
, 1998 Using data collected by the MACRO experiment during the years 1989-1996, we show evidence for the shadow of the moon in the underground cosmic ray flux with a significance of 3.6 sigma.
A. Baldini +131 more
core +4 more sources
RenDetNet: Weakly-Supervised Shadow Detection with Shadow Caster Verification
Existing shadow detection models struggle to differentiate dark image areas from shadows. In this paper, we tackle this issue by verifying that all detected shadows are real, i.e. they have paired shadow casters. We perform this step in a physically-accurate manner by differentiably re-rendering the scene and observing the changes stemming from carving
Kubiak, Nikolina +5 more
openaire +2 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
GNSS Shadow Matching: The Challenges Ahead [PDF]
, 2015 GNSS shadow matching is a new technique that uses 3D mapping to improve positioning accuracy in dense urban areas from tens of meters to within five meters, potentially less.
Adjrad, M, Ellul, C, Groves, PD, Wang, L
core
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
A Moving Shadow Elimination Method Based on Fusion of Multi-Feature
IEEE Access, 2020 Moving shadow elimination plays an important role in the field of moving object detection. However, the accuracy of shadow elimination is an open question, due to illumination and complex texture.
Hongrui Zhang +4 more
doaj +1 more source
Decentralization and the Shadow Economy: Oates Meets Allingham-Sandmo [PDF]
This paper studies the impact of decentralization on the shadow economy. We argue that decentralization may decrease the size of the shadow economy mainly through two transmission channels: (1) Decentralization enhancing public sector efficiency ...
Andreas Bühn +2 more
core
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source