Results 51 to 60 of about 47,342 (264)

Shadow links

Journal of Economic Theory, 2018
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Förster, Manuel, Mauleon, Ana, Vannetelbosch, Vincent   +2 more
openaire   +5 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Structures Detection Based on CLSK Model Combined With Shadow Information Using High-Resolution Remote Sensing Images

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
In light of rapid economic and urban growth, the proliferation of structures including transmission towers, signal poles, and wind generators has become evident.
Chengrui Wang, Kai Xu, Rong Li, Zhiyong Zhang, Kun Qin, Yubin Xu   +5 more
doaj   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Soft bilateral filtering volumetric shadows using cube shadow maps.

PLoS ONE, 2017
Volumetric shadows often increase the realism of rendered scenes in computer graphics. Typical volumetric shadows techniques do not provide a smooth transition effect in real-time with conservation on crispness of boundaries. This research presents a new
Hatam H Ali, Mohd Shahrizal Sunar, Hoshang Kolivand   +2 more
doaj   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

A Bayesian analysis of classical shadows

npj Quantum Information, 2021
The method of classical shadows proposed by Huang, Kueng, and Preskill heralds remarkable opportunities for quantum estimation with limited measurements.
Joseph M. Lukens, Kody J. H. Law, Ryan S. Bennink   +2 more
doaj   +1 more source

Scattering shadows

American Journal of Physics
We discuss the regions forbidden to classical scattering trajectories by repulsive potentials. We give explicit results for the asymptotic form of these regions, far from the scattering center, in terms of the scattering angle function. We account for divergent total cross sections on the basis of these results.
Curtright, Thomas, Verma, Gaurav
openaire   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Single Channel Slow Moving Target Detection Method for Terahertz Video Synthetic Aperture Radar Based on Shadows and Spots

Remote Sensing
Terahertz waves are located in the “transition zone” between millimeter waves and infrared light. Terahertz video synthetic aperture radar (THz-ViSAR) utilizes the high operating frequency, strong radar cross-section intensity, and high azimuth ...
Xiaofan Li, Shuangxun Li, Bin Deng, Qiang Fu, Hongqiang Wang   +4 more
doaj   +1 more source