Results 71 to 80 of about 82,188 (311)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Soft bilateral filtering volumetric shadows using cube shadow maps.
PLoS ONE, 2017 Volumetric shadows often increase the realism of rendered scenes in computer graphics. Typical volumetric shadows techniques do not provide a smooth transition effect in real-time with conservation on crispness of boundaries. This research presents a new
Hatam H Ali +2 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Constraining Nonsingular Black Holes with a Minkowski Core via EHT Observations of M87* and Sgr A*
UniverseThe Event Horizon Telescope (EHT) imaging of M87* and Sgr A* provides a unique opportunity to test spacetime geometries in the strong-field regime.
Ming-Xin Li +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Economía global: FAR Frohn & Rojas
ARQ, 2012 Materialmente irrelevante (apenas 23 kg de espejos, focos LED y motores minúsculos), el proyecto de esta galería de sombras plantea preguntas sobre el uso de diferentes recursos, su escasez y su abundancia.Almost immaterial (mirrors, LED bulbs and tiny ...
Marc Frohn, Mario Rojas
doaj
Penumbra Shadow Representation in Photovoltaics: Comparing Dynamic and Constant Intensity
Applied SciencesThis study is the first to directly compare natural dynamic penumbra shadows with experimentally replicated constant-intensity shadows on photovoltaic modules, providing new insights into the limitations of conventional shadow approximations found in the
Matthew Axisa +2 more
doaj +1 more source
Single image shadow removal by optimization using non-shadow anchor values
Computational Visual Media, 2019 Shadow removal has evolved as a pre-processing step for various computer vision tasks. Several studies have been carried out over the past two decades to eliminate shadows from videos and images. Accurate shadow detection is an open problem because it is
Saritha Murali +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source