Results 91 to 100 of about 407,307 (292)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Primal and Shadow functions, Dual and Dual-Shadow functions for a circular crack and a circular 90 degree V-notch with Neumann boundary conditions

, 2012
This report presents explicit analytical expressions for the primal, primal shadows, dual and dual shadows functions for the Laplace equation in the vicinity of a circular singular edge with Neumann boundary conditions on the faces that intersect at the ...
Costabel, Martin, Dauge, Monique, Shannon, Samuel, Yosibash, Zohar   +3 more
core   +1 more source

Asphalted Road Temperature Variations Due to Wind Turbine Cast Shadows

Sensors, 2009
The contribution of this paper is a technique that in certain circumstances allows one to avoid the removal of dynamic shadows in the visible spectrum making use of images in the infrared spectrum.
Jonay Toledo, Marta Sigut, Leopoldo Acosta, Rafael Arnay   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Shadowing for Pronunciation Development : Haptic-Shadowing and IPA-Shadowing [PDF]

The Journal of AsiaTEFL, 2018
Shadowing was introduced to foreign language teaching in the 1990s and since then it has been researched in EFL teaching contexts. Shadowing has been used as a listening task, and its effectiveness on listening comprehension has been acknowledged. However, its effect on pronunciation development remains unclear.
openaire   +1 more source

Automatic Cloud and Shadow Detection in Optical Satellite Imagery Without Using Thermal Bands—Application to Suomi NPP VIIRS Images over Fennoscandia

Remote Sensing, 2017
In land monitoring applications, clouds and shadows are considered noise that should be removed as automatically and quickly as possible, before further analysis.
Eija Parmes, Yrjö Rauste, Matthieu Molinier, Kaj Andersson, Lauri Seitsonen   +4 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Tracking-Based Non-Parametric Background-Foreground Classification in a Chromaticity-Gradient Space

, 2010
This work presents a novel background-foreground classification technique based on adaptive non-parametric kernel estimation in a color-gradient space of components.
Cuevas Rodríguez, Carlos, García Santos, Narciso   +1 more
core   +1 more source

Single-Image Building Height Estimation Using Spatial Distribution-Aware Optimization in Complex Urban Areas

Remote Sensing
Building height is a fundamental parameter for characterizing urban three-dimensional structure and supporting applications such as urban planning, population estimation, and energy assessment.
Yakun Xie, Jiaxing Tu, Yaoji Zhao, Ruifeng Xia, Wen Song, Dejun Feng, Ya Hu   +6 more
doaj   +1 more source