Results 71 to 80 of about 22,146 (252)

Multi‐Targeting Carnosic Acid Kills Drug‐Resistant Helicobacter pylori With Narrow‐Spectrum Activity

Advanced Science, EarlyView.
Carnosic acid selectively eradicates drug‐resistant Helicobacter pylori through a multi‐targeted mechanism involving urease inhibition, membrane disruption, and biofilm eradication. It exhibits no detectable resistance, potent in vivo efficacy, and minimal impact on gut microbiota, positioning it as a promising narrow‐spectrum lead compound against ...
Yuefan Bai, Hongming Huang, Xudong Hang, Shanwei Hu, Qian Tong, Jingchen Xu, Jia Jia, Hongkai Bi   +7 more
wiley   +1 more source

Shannon Entropy for Neutrosophic Information

CoRR, 2018
The paper presents an extension of Shannon entropy for neutrosophic information. This extension uses a new formula for distance between two neutrosophic triplets. In addition, the obtained results are particularized for bifuzzy, intuitionistic and paraconsistent fuzzy information.
openaire   +3 more sources

Conformational Snapshots of CydDC in a Native Lipid Bilayer Coupling Heme Transport to Antibiotic Resistance

Advanced Science, EarlyView.
Phylogenetic and biochemical analyses of the heme transporter CydDC reveal its functional conservation throughout bacterial evolution and demonstrate its unique asymmetric allosteric mechanism. Furthermore, impairment of CydDC function directly affects bacterial antibiotic resistance and likely compromises antibiotic efficacy through drug efflux.
Lili Yang, Changbin Zhang, Mengyuan Lyu, Yongbo Luo, Jierou Zhang, Yujiao Chen, Lintao Luo, Wen Qiao, Xiangyangpeng Li, Yu Zhou, Zhongling Wei, Yuling Xiao, Qian Niu, Juan Zhou, Guanglin He, Binwu Ying, Zhaoming Su, Hao Chen, Xiaodi Tang, Haohao Dong   +19 more
wiley   +1 more source

Learn your entropy from informative data: An axiom ensuring the consistent identification of generalized entropies

Physical Review Research
Shannon entropy, a cornerstone of information theory, statistical physics, and inference methods, is uniquely identified by the Shannon-Khinchin or Shore-Johnson axioms.
Andrea Somazzi, Diego Garlaschelli
doaj   +1 more source

Is the Voronoi Entropy a True Entropy? Comments on “Entropy, Shannon’s Measure of Information and Boltzmann’s H-Theorem”, Entropy 2017, 19, 48

Entropy, 2019
The goal of this comment note is to express our considerations about the recent paper by A. Ben Naim (Entropy 2017, 19, 48). We strongly support the distinguishing between the Shannon measure of information and the thermodynamic entropy, suggested in the
Edward Bormashenko, Mark Frenkel, Irina Legchenkova   +2 more
doaj   +1 more source

The Shannon Entropy of a Histogram

, 2022
Preprint for work presented at the Royal Statistical Society Annual Meeting, Aberdeen, September ...
Watts, Stephen, Crow, Lisa
openaire   +2 more sources

A Phase‐Resolved Geometric Deep Learning Framework Maps Structural Determinants of Disease‐Associated Protein Aggregation and Guides Suppressor Design

Advanced Science, EarlyView.
SKALE 2.0 maps disease‐associated protein aggregation as a phase‐resolved structural process, linking mutation‐induced geometric perturbations to nucleation, elongation, and suppressor design. Across neurodegenerative proteins, the framework reveals cryptic aggregation vulnerabilities, separates phase‐concordant and phase‐switching mutations, and ...
Jia Shen Sio, Wei Xuan Wilson Loo, Yan Shan Loo, Wen Xin Tan, Hui Xuan Lim, Huitao Liu, Chen Seng Ng   +6 more
wiley   +1 more source

Using Shannon Entropy and Contagion Index to Interpret Pattern Self-Organization in a Dynamic Vegetation-Sand Model

IEEE Access, 2020
Vegetation pattern is one of the most important self-organized patterns in ecological systems. The formation mechanism of vegetation patterns has been attributed to dynamic bifurcations, while from the external perspective, the regularity of patterns ...
Feifan Zhang, Lei Yao, Wenjiao Zhou, Qinjing You, Huayong Zhang   +4 more
doaj   +1 more source

A Single‐Cell Transcriptomic Atlas of the Ovine Rumen Microbiome Characterizes Lineage‐Specific Metabolic Shifts Associated with Host Heat Tolerance

Advanced Science, EarlyView.
An optimized single‐cell transcriptomic framework profiles over 60 000 cells to map the ovine rumen microbiome, partitioning the ecosystem into seven cross‐species functional clusters. In heat‐resistant hosts, a lineage‐specific metabolic shift in Anaerovibrio lipolyticus toward a highly glycolytic phenotype contributes to a “nutritional sparing ...
Sanbao Zhang, Qinyang Jiang, Junjie Ma, Jianwei Zou, Fan Wang, Feifei Lv, Yanna Huang, Yongcheng Wang, Ziye Xu   +8 more
wiley   +1 more source

Inequalities for Shannon Entropy and Kolmogorov Complexity

Journal of Computer and System Sciences, 2000
It was mentioned by \textit{A. N. Kolmogorov} [IEEE Trans. Inf. Theory IT-14, 662-664 (1968; Zbl 0167.47601)] that the properties of algorithmic complexity and Shannon entropy are similar. We investigate one aspect of this similarity. Namely, we are interested in linear inequalities that are valid for Shannon entropy and for Kolmogorov complexity.
Daniel Hammer, Andrei Romashchenko, Alexander Shen 0001, Nikolai K. Vereshchagin   +3 more
openaire   +1 more source