Results 141 to 150 of about 1,014,609 (340)

ACCURATE REGISTRATION BETWEEN ULTRA-WIDE-FIELD AND NARROW ANGLE RETINA IMAGES WITH 3D EYEBALL SHAPE OPTIMIZATION. [PDF]

Proc Int Conf Image Proc, 2023
Zhang J, Wen B, Kalaw FGP, Cavichini M, Bartsch DG, Freeman WR, Nguyen TQ, An C.   +7 more
europepmc   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Genetic algorithm shape optimization to manipulate the nonlinear response of a clamped-clamped beam. [PDF]

Heliyon, 2022
Mollik T, Geng Y, Shougat MREU, Fitzgerald T, Perkins E.   +4 more
europepmc   +1 more source

Shape optimization of eigenfrequencies in MEMS gyroscopes [PDF]

Daniel Schiwietz, Marian Hörsting, Eva M. Weig, Peter Degenfeld-Schonburg, Matthias Wenzel   +4 more
openalex   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

PSO-Incorporated Hybrid Artificial Hummingbird Algorithm with Elite Opposition-Based Learning and Cauchy Mutation: A Case Study of Shape Optimization for CSGC-Ball Curves. [PDF]

Biomimetics (Basel), 2023
Chen K, Chen L, Hu G.
europepmc   +1 more source

Interface Shape Design Optimization of Inlay Structures in Frequency Response Problem

, 2016
Jin-Xing Shi, Masatoshi SHIMODA
openalex   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Design and Shape Optimization of Strain Gauge Load Cell for Axial Force Measurement for Test Benches. [PDF]

Sensors (Basel), 2022
Al-Dahiree OS, Tokhi MO, Hadi NH, Hmoad NR, Ghazilla RAR, Yap HJ, Albaadani EA.   +6 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source