Results 51 to 60 of about 1,014,609 (340)

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Morphology-Embedded Synergistic Optimization of Thermal and Mechanical Performance in Free-Form Single-Layer Grid Structures

Technologies
Free-form grid structures offer both aesthetic appeal and structural efficiency in long-span roof design and application, yet the potential of morphological design to optimize thermal performance has been long overlooked.
Bowen Hou, Baoshi Jiang, Bangjian Wang
doaj   +1 more source

Shape optimization of pressurized air bearings [PDF]

, 2002
Use of externally pressurized air bearings allows for the design of mechanical systems requiring extreme precision in positioning. One application is the fine control for the positioning of mirrors in large-scale optical telescopes.
Howell, Peter, Kedzior, M., Kramer, P., Please, Colin, Rossi, Louis, Saintval, W., Salazar, D., Witelski, T.   +7 more
core  

Second-order Shape Optimization for Geometric Inverse Problems in Vision [PDF]

, 2014
We develop a method for optimization in shape spaces, i.e., sets of surfaces modulo re-parametrization. Unlike previously proposed gradient flows, we achieve superlinear convergence rates through a subtle approximation of the shape Hessian, which is ...
Balzer, J., Soatto, S.
core   +1 more source

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm, Imme Haubitz, Rita Beier, Martin Zimmermann, Andrej Lissat, Peter Bader, Matthias Eyrich, Jan‐Henning Klusmann, Matthias Wölfl, Paul‐Gerhardt Schlegel, Verena Wiegering   +10 more
wiley   +1 more source

Shape optimization of viscous flow field considering fluid-structure-interactive

Nihon Kikai Gakkai ronbunshu, 2021
This paper presents numerical solution to a shape optimization of viscous flow field for stationary fluid-structure-interactive (FSI) fields. In the FSI analysis, a weak coupled analysis is used to alternately analyze the governing equations of the flow ...
Eiji KATAMINE, Ryuga KAWAI, Hibiki YAMASHITA   +2 more
doaj   +1 more source

Incidence and Risk Factors of Serious Osteonecrosis in Pediatric Acute Lymphoblastic Leukemia: A CYP‐C Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Osteonecrosis (ON) is a debilitating complication of acute lymphoblastic leukemia (ALL) therapy. While numerous studies have explored its incidence and associated risk factors, investigations using large‐scale cohorts remain important to characterize ON across heterogeneous populations.
Noémie de Villiers, Chantal Éthier, Caroline Laverdière, Nathalie Alos, Thai Hoa Tran, Marie‐Claude Pelland‐Marcotte   +5 more
wiley   +1 more source

Towards a Lagrange-Newton approach for PDE constrained shape optimization

, 2014
The novel Riemannian view on shape optimization developed in [Schulz, FoCM, 2014] is extended to a Lagrange-Newton approach for PDE constrained shape optimization problems.
A Novruzi, C Schillings, EJ Haug, HB Ameur, J Céa, K Eppler, M Bauer, PW Michor, PW Michor, PW Michor, R Correa, S Schmidt, S Schmidt, VH Schulz   +13 more
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source