Results 71 to 80 of about 264,907 (315)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Space Mapping for PDE Constrained Shape Optimization

open access: yes, 2023
The space mapping technique is used to efficiently solve complex optimization problems. It combines the accuracy of fine model simulations with the speed of coarse model optimizations to approximate the solution of the fine model optimization problem. In
Sebastian Blauth, Blauth, Sebastian
core   +1 more source

Parameter Selection of Local Search Algorithm for Design Optimization of Automotive Rubber Bumper

open access: yesApplied Sciences, 2020
In rubber bumper design, the most important mechanical property of the product is the force–displacement curve under compression and its fulfillment requires an iterative design method.
Dávid Huri, Tamás Mankovits
doaj   +1 more source

Fundamental investigation on free-form optimization of vibration lures

open access: yesNihon Kikai Gakkai ronbunshu, 2021
Lure fishing is a special fishing method that using artificial fishing lures as fish baits and has become more and more popular all over the world. Vibration lures are a regular item among fishing lures that perform vibration action in the water for ...
Jin-Xing SHI   +2 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Shape optimization for Stokes problem with threshold slip boundary conditions

open access: yes, 2017
This paper deals with shape optimization of systems governed by the Stokes flow with threshold slip boundary conditions. The stability of solutions to the state problem with respect to a class of domains is studied.
Haslinger Jaroslav   +2 more
core   +1 more source

Shape optimization of joining interface profile for maximizing the tensile load carrying capacity of scarf jointed plates of dissimilar materials

open access: yesNihon Kikai Gakkai ronbunshu, 2021
The shape optimization of joining interface profile is performed for maximizing the tensile load carrying capacity of scarf jointed plates of dissimilar materials.
Hideki SEKINE, Hiroshi SHIRAHATA
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Shape and reinforcement optimization of underground tunnels

open access: yes, 2010
Design of support system and selecting an optimum shape for the opening are two important steps in designing excavations in rock masses. Currently selecting the shape and support design are mainly based on designer's judgment and experience.
Ghabraie, Kazem   +3 more
core   +1 more source

Fully turbulent discrete adjoint solver for non-ideal compressible flow applications

open access: yesJournal of the Global Power and Propulsion Society, 2017
Non-Ideal Compressible Fluid-Dynamics (NICFD) has recently been established as a sector of fluid mechanics dealing with the flows of dense vapors, supercritical fluids, and two-phase fluids, whose properties significantly depart from those of the ideal ...
Salvatore Vitale   +4 more
doaj   +1 more source

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