Results 51 to 60 of about 241,381 (266)

Parameter-Free Shape Optimization: Various Shape Updates for Engineering Applications

open access: yesAerospace, 2023
In the last decade, parameter-free approaches to shape optimization problems have matured to a state where they provide a versatile tool for complex engineering applications.
Lars Radtke   +6 more
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari   +5 more
wiley   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

Multi-objective shape optimization of developable Bézier-like surfaces using non-dominated sorting genetic algorithm

open access: yesMechanics & Industry, 2023
The shape optimization design of the developable surface is an important research topic in CAD/CAM, and it is widely used in engineering manufacturing.
Lu Jing   +3 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Parameter Selection of Local Search Algorithm for Design Optimization of Automotive Rubber Bumper

open access: yesApplied Sciences, 2020
In rubber bumper design, the most important mechanical property of the product is the force–displacement curve under compression and its fulfillment requires an iterative design method.
Dávid Huri, Tamás Mankovits
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Fundamental investigation on free-form optimization of vibration lures

open access: yesNihon Kikai Gakkai ronbunshu, 2021
Lure fishing is a special fishing method that using artificial fishing lures as fish baits and has become more and more popular all over the world. Vibration lures are a regular item among fishing lures that perform vibration action in the water for ...
Jin-Xing SHI   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Suitable Spaces for Shape Optimization [PDF]

open access: yesApplied Mathematics & Optimization, 2021
AbstractThe differential-geometric structure of the manifold of smooth shapes is applied to the theory of shape optimization problems. In particular, a Riemannian shape gradient with respect to the first Sobolev metric and the Steklov–Poincaré metric are defined.
openaire   +3 more sources

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